RA CAPITAL MANAGEMENT, L.P. Q1 2025 Filing
Filed May 15, 2025
Portfolio Value
$6.0B
Holdings
85
Report Date
Q1 2025
Filing Type
13F-HR
All Holdings (85 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | ASNDASCENDIS PHARMA A/S - ADR | 10,281,496 | $1.6T | 26761.82% | |
| 2 | PCVXVAXCYTE INC | 12,189,149 | $460.3B | 7686.52% | |
| 3 | RYTMRHYTHM PHARMACEUTICALS INC | 6,084,412 | $322.3B | 5382.37% | |
| 4 | JANXJANUX THERAPEUTICS INC | 11,189,693 | $302.1B | 5045.53% | |
| 5 | NAMSNEWAMSTERDAM PHARMA CO NV | 10,138,938 | $207.5B | 3466.05% | |
| 6 | ACLXARCELLX INC | 3,036,527 | $199.2B | 3326.64% | |
| 7 | EWTXEDGEWISE THERAPEUTICS INC | 8,909,091 | $196.0B | 3273.26% | |
| 8 | RNAAVIDITY BIOSCIENCES INC | 6,300,408 | $186.0B | 3106.06% | |
| 9 | WVEWAVE LIFE SCIENCES LTD | 18,202,009 | $147.1B | 2456.15% | |
| 10 | ETNBGBP89BIO INC | 19,889,683 | $144.6B | 2414.83% | |
| 11 | SPRYARS PHARMACEUTICALS INC | 10,860,977 | $136.6B | 2281.78% | |
| 12 | SIONSIONNA THERAPEUTICS INC | 10,445,322 | $109.3B | 1824.64% | |
| 13 | LENZLENZ THERAPEUTICS INC | 4,178,823 | $107.4B | 1794.24% | |
| 14 | DYNDYNE THERAPEUTICS INC | 9,714,392 | $101.6B | 1696.96% | |
| 15 | TYRATYRA BIOSCIENCES INC | 10,637,290 | $98.9B | 1652.11% | |
| 16 | MLYSMINERALYS THERAPEUTICS INC | 6,147,280 | $97.6B | 1630.26% | |
| 17 | GONGERON CORP | 60,379,366 | $96.0B | 1603.28% | |
| 18 | RXSTRXSIGHT INC | 3,743,018 | $94.5B | 1578.37% | |
| 19 | BCAXBICARA THERAPEUTICS INC | 6,955,993 | $90.6B | 1513.66% | |
| 20 | IRONDISC MEDICINE INC | 1,577,106 | $78.3B | 1307.43% | |
| 21 | GHRSGH RESEARCH PLC | 6,944,648 | $76.6B | 1279.24% | |
| 22 | APGEAPOGEE THERAPEUTICS INC | 1,569,491 | $58.6B | 979.24% | |
| 23 | DNTHDIANTHUS THERAPEUTICS INC | 2,866,733 | $52.0B | 868.46% | |
| 24 | ZLABZAI LAB LTD-ADR | 1,295,040 | $46.8B | 781.62% | |
| 25 | DAWNDAY ONE BIOPHARMACEUTICALS I | 5,755,577 | $45.6B | 762.23% | |
| 26 | SEPNSEPTERNA INC | 6,995,858 | $40.5B | 676.46% | |
| 27 | TRMLTOURMALINE BIO INC | 2,538,925 | $38.6B | 644.92% | |
| 28 | CLYMCLIMB BIO INC | 31,419,267 | $38.3B | 640.15% | |
| 29 | SRRKSCHOLAR ROCK HOLDING CORP | 1,136,453 | $36.5B | 610.18% | |
| 30 | URGNUROGEN PHARMA LTD | 3,206,271 | $35.5B | 592.22% | |
| 31 | ARTVARTIVA BIOTHERAPEUTICS INC | 9,853,302 | $29.6B | 493.66% | |
| 32 | FULCFULCRUM THERAPEUTICS INC | 10,229,099 | $29.5B | 491.99% | |
| 33 | VORVOR BIOPHARMA INC | 39,646,039 | $28.4B | 475.06% | |
| 34 | CATBUSDASTRIA THERAPEUTICS INC | 5,105,213 | $27.3B | 455.28% | |
| 35 | KURAKURA ONCOLOGY INC | 4,004,610 | $26.4B | 441.40% | |
| 36 | GPCRSTRUCTURE THERAPEUTICS INC | 1,517,418 | $26.3B | 438.66% | |
| 37 | CDTXCIDARA THERAPEUTICS INC | 1,092,796 | $23.5B | 393.11% | |
| 38 | AVTEAEROVATE THERAPEUTICS INC | 9,192,092 | $23.1B | 385.31% | |
| 39 | IDYAIDEAYA BIOSCIENCES INC | 1,347,252 | $22.1B | 368.54% | |
| 40 | 5E7ITEOS THERAPEUTICS INC | 3,649,057 | $21.8B | 363.81% | |
| 41 | TVTXTRAVERE THERAPEUTICS INC | 1,150,000 | $20.6B | 344.16% | |
| 42 | NKTXNKARTA INC | 10,805,129 | $19.9B | 332.03% | |
| 43 | GKOSGLAUKOS CORP | 190,256 | $18.7B | 312.71% | |
| 44 | MNPRMONOPAR THERAPEUTICS INC | 511,207 | $18.6B | 310.84% | |
| 45 | MTSRMETSERA INC | 675,525 | $18.4B | 307.08% | |
| 46 | EYPTEYEPOINT PHARMACEUTICALS INC | 3,181,818 | $17.2B | 288.00% | |
| 47 | TXG10X GENOMICS INC-CLASS A | 1,944,247 | $17.0B | 283.46% | |
| 48 | ACRVACRIVON THERAPEUTICS INC | 8,340,508 | $16.9B | 282.76% | |
| 49 | ELVNENLIVEN THERAPEUTICS INC | 848,986 | $16.7B | 279.03% | |
| 50 | ABOSACUMEN PHARMACEUTICALS INC | 14,932,063 | $16.4B | 274.31% | |
| 51 | SLDBSOLID BIOSCIENCES INC | 4,330,446 | $16.0B | 267.58% | |
| 52 | CBLLCERIBELL INC | 824,582 | $15.8B | 264.54% | |
| 53 | NRIXNURIX THERAPEUTICS INC | 1,333,333 | $15.8B | 264.53% | |
| 54 | IM8NINSMED INC | 200,000 | $15.3B | 254.81% | |
| 55 | TSHATAYSHA GENE THERAPIES INC | 10,872,503 | $15.1B | 252.39% | |
| 56 | PEPGPEPGEN INC | 10,689,545 | $15.0B | 250.82% | |
| 57 | FDMT4D MOLECULAR THERAPEUTICS IN | 4,563,211 | $14.7B | 246.15% | |
| 58 | TARAPROTARA THERAPEUTIC INC | 3,400,000 | $14.5B | 241.89% | |
| 59 | LRMRLARIMAR THERAPEUTICS INC | 6,045,351 | $13.0B | 217.06% | |
| 60 | ELDNELEDON PHARMACEUTICALS INC | 3,566,338 | $12.1B | 201.90% | |
| 61 | ALECALECTOR INC | 9,695,228 | $11.9B | 199.15% | |
| 62 | SERASERA PROGNOSTICS INC-A | 3,032,808 | $11.2B | 186.39% | |
| 63 | MBXMBX BIOSCIENCES INC | 1,511,334 | $11.2B | 186.27% | |
| 64 | BCYCBICYCLE THERAPEUTICS PLC-ADR | 1,093,477 | $9.3B | 155.04% | |
| 65 | RCUSARCUS BIOSCIENCES INC | 1,136,364 | $8.9B | 148.97% | |
| 66 | SRZNSURROZEN INC | 679,130 | $7.9B | 132.24% | |
| 67 | IMTXIMMATICS NV | 1,750,000 | $7.9B | 131.81% | |
| 68 | AVTXAVALO THERAPEUTICS INC | 967,000 | $7.7B | 129.36% | |
| 69 | —PERCEPTIVE CAPITAL SOLUTIONS | 750,000 | $7.7B | 129.01% | |
| 70 | DRUGBright Minds Biosciences Inc | 206,427 | $7.4B | 124.35% | |
| 71 | ACRSACLARIS THERAPEUTICS INC | 4,666,667 | $7.1B | 119.24% | |
| 72 | ACHCACADIA HEALTHCARE CO INC | 217,000 | $6.6B | 109.88% | |
| 73 | BBNXBETA BIONICS INC | 500,000 | $6.1B | 102.21% | |
| 74 | XNCRXENCOR INC | 575,000 | $6.1B | 102.17% | |
| 75 | HOWLWEREWOLF THERAPEUTICS INC | 6,144,881 | $6.0B | 99.77% | |
| 76 | TORCEURADICET BIO INC | 7,541,000 | $5.7B | 95.08% | |
| 77 | HUMAHUMACYTE INC | 3,312,356 | $5.6B | 94.32% | |
| 78 | ZURAZURA BIO LTD | 3,217,503 | $4.2B | 69.32% | |
| 79 | BIOABIOAGE LABS INC | 1,052,494 | $4.0B | 66.09% | |
| 80 | BOLDBOUNDLESS BIO INC | 2,180,631 | $3.3B | 54.99% | |
| 81 | NAMSNEWAMSTERDAM PHARMA CO NV-27 | 333,333 | $3.0B | 50.05% | |
| 82 | STROSUTRO BIOPHARMA INC | 4,434,637 | $2.9B | 48.18% | |
| 83 | LXEOLEXEO THERAPEUTICS INC | 546,554 | $1.9B | 31.67% | |
| 84 | CTMXCYTOMX THERAPEUTICS INC | 1,000,000 | $635.8M | 10.62% | |
| 85 | SCLXUSDSCILEX HOLDING CO | 1,036,218 | $257.5M | 4.30% |