Who Owns Bicycle Therapeutics plc (BCYC)?Hedge Fund & Institutional Holders

$5.00+0.22 (+4.60%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$7.706800024556e+270T

% of Float Held

—

QoQ Change in Holders

+9 / -3

Price History

$4.78$10.46$16.14$21.83$27.51Sep 24Jun 25Mar 26

BCYC — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
PRINCIPAL FINANCIAL GROUP INCNew Position+1.1M+$8.1B
SCHRODER INVESTMENT MANAGEMENT GROUPNew Position+585K+$3.0B
Birchview Capital, LPIncreased+309K+$2.1B
MOORE CAPITAL MANAGEMENT, LPIncreased+150K+$979.5M
Long Focus Capital Management, LLCIncreased+214K+$581.3M
Virtus Investment Advisers, LLCIncreased+23K+$150.7M
Forefront Analytics, LLCNew Position+13K+$94.0M
UBS Group AGIncreased+14K+$92.0M
Invesco Ltd.New Position+10K+$71.0M
GSK plcNew Position+1.5M+$10.8M
MONIMUS CAPITAL MANAGEMENT, LPIncreased+9K+$4.4M
BNP Paribas Asset Management Holding S.A.New Position+568K+$4.0M
HighMark Wealth Management LLCNew Position+435+$3.0M
Farther Finance Advisors, LLCNew Position+218+$1.0M
FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.New Position+135K+$953K

BCYC — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
MILLENNIUM MANAGEMENT LLCDecreased-728K-$6.2B
Point72 Asset Management, L.P.Decreased-354K-$3.3B
Jefferies Financial Group Inc.Decreased-105K-$3.1B
Legal & General Group PlcDecreased-189K-$1.5B
TWO SIGMA INVESTMENTS, LPDecreased-53K-$1.4B
MANUFACTURERS LIFE INSURANCE COMPANY, THEDecreased-13K-$1.1B
Cubist Systematic Strategies, LLCClosed Position-103K-$800.4M
JANE STREET GROUP, LLCDecreased-39K-$793.0M
TD ASSET MANAGEMENT INCDecreased-30K-$378.4M
Eversept Partners, LPDecreased-16K-$239.0M
TWO SIGMA ADVISERS, LPDecreased-11K-$212.9M
PINNACLE ASSOCIATES LTDDecreased-6K-$173.8M
AMERIPRISE FINANCIAL INCClosed Position-15K-$115.9M
Squarepoint Ops LLCClosed Position-13K-$102.6M
ROYAL BANK OF CANADADecreased-2K-$99.0M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1BAKER BROS. ADVISORS LP10,885,357$77.1B451.25%Share
2FCPM III SERVICES B.V.3,468,430$24.6B3.22%Share
3WESTFIELD CAPITAL MANAGEMENT CO LP3,016,026$21.0B87.48%Share
4Siren, L.L.C.2,012,752$14.3B0.43%Share
5Long Focus Capital Management, LLC1,633,091$11.6B0.30%Share
6PRINCIPAL FINANCIAL GROUP INC1,148,272$8.1B4.15%Share
7Candriam S.C.A.1,192,279$8.0B39.84%Share
8RENAISSANCE TECHNOLOGIES LLC566,600$4.0B6.21%Share
9Birchview Capital, LP462,700$3.3B1.92%Share
10SCHRODER INVESTMENT MANAGEMENT GROUP584,770$3.0B2.27%Share
11SILVERCREST ASSET MANAGEMENT GROUP LLC476,976$3.0B20.62%Share
12BALYASNY ASSET MANAGEMENT L.P.300,000$2.0B2.54%Call
13MILLENNIUM MANAGEMENT LLC326,626$2.0B0.84%Share
14MOORE CAPITAL MANAGEMENT, LP275,000$1.9B28.03%Share
15PINNACLE ASSOCIATES LTD190,480$1.3B17.30%Share
16Eversept Partners, LP178,915$1.3B0.06%Share
17PLATINUM INVESTMENT MANAGEMENT LTD184,603$1.0B0.23%Share
18TWO SIGMA ADVISERS, LP146,100$1.0B1.94%Share
19CITADEL ADVISORS LLC266,154$1.0B0.15%Share
20TD ASSET MANAGEMENT INC147,992$1.0B0.80%Share
21MONIMUS CAPITAL MANAGEMENT, LP93,840$664.0M0.44%Share
22Virtus Investment Advisers, LLC35,709$252.0M0.07%Share
23State of New Jersey Common Pension Fund D20,105$142.0M0.51%Share
24UBS Group AG15,778$111.0M0.02%Share
25PORTLAND INVESTMENT COUNSEL INC.15,000$106.0M0.03%Share
26HORIZON KINETICS ASSET MANAGEMENT LLC13,792$97.0M1.31%Share
27Forefront Analytics, LLC13,371$94.0M0.08%Share
28Crossmark Global Holdings, Inc.11,399$80.0M1.15%Share
29Invesco Ltd.10,092$71.0M0.01%Share
30UBS Group AG5,148$36.0M0.01%Share
31UBS Group AG4,750$33.0M0.01%Share
32ASSETMARK, INC3,628$25.0M0.05%Share
33ACADIAN ASSET MANAGEMENT LLC1,671,258$11.0M0.02%Share
34GSK plc1,529,561$10.8M1.36%Share
35GAMMA Investing LLC1,386$9.0M0.00%Share
36PRICE T ROWE ASSOCIATES INC /MD/1,171,787$8.0M0.00%Share
37GF FUND MANAGEMENT CO. LTD.909$6.0M0.10%Share
38BNP Paribas Asset Management Holding S.A.568,225$4.0M0.00%Share
39HighMark Wealth Management LLC435$3.0M0.00%Share
40GROUP ONE TRADING LLC500$3.0M0.01%Put
41Jefferies Financial Group Inc.297,247$2.0M0.01%Share
42MORGAN STANLEY309,836$2.0M0.00%Share
43Palo Alto Investors LP221,071$1.6M0.22%Share
44Farther Finance Advisors, LLC218$1.0M0.01%Share
45BlackRock, Inc.248,713$1.0M0.02%Share
46Winch Advisory Services, LLC172$1.0M0.00%Share
47FIDEURAM - INTESA SANPAOLO PRIVATE BANKING S.P.A.134,689$953K0.03%Share
48Rangeley Capital, LLC132,000$934K0.78%Share
49DekaBank Deutsche Girozentrale30,000$801K0.00%Share
50Nan Fung Group Holdings Ltd68,943$488K0.44%Share

BCYC Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025107$190.2B+19
Q3 202588$238.5B-3
Q2 202591$222.7B-2
Q1 202593$313.0B+1
Q4 202492$549.4B+4
Q3 202488$82.1T+0
Q2 202488$73.2T+10
Q1 202478$89.9T—

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As of Q4 2025, 50 institutional investors hold BCYC (Bicycle Therapeutics plc). The largest holder is BAKER BROS. ADVISORS LP with $77.1B in shares. This quarter, 9 institutions opened new positions and 3 closed their positions.

Frequently Asked Questions

How many hedge funds own BCYC?

As of Q4 2025, 50 institutional investors report holding BCYC (Bicycle Therapeutics plc) in their 13F filings.

Who is the largest institutional holder of BCYC?

The largest institutional holder of BCYC is BAKER BROS. ADVISORS LP with $77.1B in shares.

Is institutional ownership of BCYC increasing or decreasing?

This quarter, 9 institutions opened new positions in BCYC and 3 closed their positions.