Who Owns Sutro Biopharma, Inc. (STRO)?Hedge Fund & Institutional Holders

$23.43+0.35 (+1.52%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$8.65800055480004e+160T

% of Float Held

—

QoQ Change in Holders

+15 / -4

Price History

$5.25$15.46$25.67$35.89$46.10Sep 24Jun 25Mar 26

STRO — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
BALYASNY ASSET MANAGEMENT L.P.New Position+230K+$2.0B
Point72 Asset Management, L.P.New Position+179K+$2.0B
ADAR1 Capital Management, LLCNew Position+67K+$776.0M
Opaleye Management Inc.New Position+191K+$2.2M
Spruce Street Capital LPNew Position+76K+$874K
ACUTA CAPITAL PARTNERS, LLCNew Position+67K+$780K
AJU IB Investment Co., Ltd.New Position+18K+$202K
CWM, LLCNew Position+1K+$17K
Physician Wealth Advisors, Inc.New Position+182+$2K
CITADEL ADVISORS LLCNew Position+32K+$0
State of Tennessee, Department of TreasuryNew Position+7K+$0
JANE STREET GROUP, LLCNew Position+23K+$0
Bogart Wealth, LLCNew Position+50+$0
Avion WealthNew Position+72+$0
HighMark Wealth Management LLCNew Position+23+$0

STRO — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
SUVRETTA CAPITAL MANAGEMENT, LLCClosed Position-6.5M-$5.6B
UBS Group AGDecreased-1.8M-$1.5B
TANG CAPITAL MANAGEMENT LLCDecreased-2.7M-$841.5M
JACOBS LEVY EQUITY MANAGEMENT, INCClosed Position-446K-$387.1M
TWO SIGMA INVESTMENTS, LPDecreased-350K-$344.6M
AQR CAPITAL MANAGEMENT LLCDecreased-336K-$307.8M
Fisher Asset Management, LLCDecreased-318K-$306.5M
RENAISSANCE TECHNOLOGIES LLCDecreased-1.3M-$237.3M
ROYAL BANK OF CANADADecreased-259K-$225.0M
TWO SIGMA ADVISERS, LPDecreased-222K-$207.9M
DIMENSIONAL FUND ADVISORS LPClosed Position-198K-$171.5M
RBF Capital, LLCDecreased-137K-$132.6M
LPL Financial LLCClosed Position-143K-$124.1M
NORTHERN TRUST CORPDecreased-108K-$106.0M
MARSHALL WACE, LLPDecreased-33K-$103.0M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Affinity Asset Advisors, LLC748,382$8.7B0.49%Share
2Kynam Capital Management, LP479,590$5.5B0.35%Share
3MILLENNIUM MANAGEMENT LLC418,196$4.0B1.68%Share
4Velan Capital Investment Management LP312,000$3.6B2.09%Share
5Merck & Co., Inc.272,351$3.2B1.14%Share
6Vestal Point Capital, LP243,000$2.8B0.10%Share
7Eversept Partners, LP193,571$2.2B0.11%Share
8Point72 Asset Management, L.P.179,088$2.0B2.24%Share
9ADAGE CAPITAL PARTNERS GP, L.L.C.200,000$2.0B3.03%Share
10BALYASNY ASSET MANAGEMENT L.P.230,049$2.0B2.54%Share
11TANG CAPITAL MANAGEMENT LLC139,617$1.6B0.08%Share
12RENAISSANCE TECHNOLOGIES LLC122,865$1.0B1.55%Share
13ADAR1 Capital Management, LLC67,077$776.0M0.06%Share
14Shay Capital LLC24,255$280.0M0.03%Share
15Invesco Ltd.16,970$196.0M0.03%Share
16UBS Group AG7,860$90.0M0.01%Share
17VANGUARD GROUP INC324,457$3.0M0.04%Share
18ACADIAN ASSET MANAGEMENT LLC337,953$3.0M0.00%Share
19Samsara BioCapital, LLC204,503$2.4M0.24%Share
20Opaleye Management Inc.190,671$2.2M0.29%Share
21BlackRock, Inc.96,789$1.0M0.02%Share
22GSA CAPITAL PARTNERS LLP89,067$1.0M0.09%Share
23GROUP ONE TRADING LLC100$1.0M0.00%Call
24Spruce Street Capital LP75,594$874K0.29%Share
25ACUTA CAPITAL PARTNERS, LLC67,451$780K0.53%Share
26AJU IB Investment Co., Ltd.17,500$202K0.89%Share
27CWM, LLC1,499$17K0.00%Share
28FNY Investment Advisers, LLC1,000$11K0.00%Share
29Physician Wealth Advisors, Inc.182$2K0.00%Share
30WELLS FARGO & COMPANY/MN100$00.00%Share
31Fisher Asset Management, LLC35,305$00.00%Share
32ROYAL BANK OF CANADA11$00.00%Share
33RBF Capital, LLC15,272$00.00%Share
34AQR CAPITAL MANAGEMENT LLC84$00.00%Share
35AQR CAPITAL MANAGEMENT LLC56$00.00%Share
36AQR CAPITAL MANAGEMENT LLC191$00.00%Share
37AQR CAPITAL MANAGEMENT LLC17,703$00.00%Share
38TWO SIGMA INVESTMENTS, LP46,492$00.00%Share
39PNC FINANCIAL SERVICES GROUP, INC.62$00.00%Share
40UBS Group AG10$00.00%Share
41State of Tennessee, Department of Treasury7,400$00.00%Share
42TWO SIGMA ADVISERS, LP17,580$00.00%Share
43FMR LLC1,108$00.00%Share
44BANK OF AMERICA CORP /DE/12$00.00%Share
45BANK OF AMERICA CORP /DE/4,200$00.00%Share
46NORTHERN TRUST CORP14,379$00.00%Share
47OMERS ADMINISTRATION Corp11,023$00.00%Share
48CITIGROUP INC1,043$00.00%Share
49JPMORGAN CHASE & CO206$00.00%Share
50JPMORGAN CHASE & CO535$00.00%Share

STRO Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202562$40.0B-11
Q3 202573$34.6B-14
Q2 202587$26.8B-27
Q1 2025114$31.9B-5
Q4 2024119$71.6B+2
Q3 2024117$3.5T+9
Q2 2024108$2.1T+5
Q1 2024103$286.2T—

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As of Q4 2025, 50 institutional investors hold STRO (Sutro Biopharma, Inc.). The largest holder is Affinity Asset Advisors, LLC with $8.7B in shares. This quarter, 15 institutions opened new positions and 4 closed their positions.

Frequently Asked Questions

How many hedge funds own STRO?

As of Q4 2025, 50 institutional investors report holding STRO (Sutro Biopharma, Inc.) in their 13F filings.

Who is the largest institutional holder of STRO?

The largest institutional holder of STRO is Affinity Asset Advisors, LLC with $8.7B in shares.

Is institutional ownership of STRO increasing or decreasing?

This quarter, 15 institutions opened new positions in STRO and 4 closed their positions.