Who Owns Wave Life Sciences Ltd. (WVE)?Hedge Fund & Institutional Holders

$12.95-0.40 (-3.00%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$3.10176309451203e+243T

% of Float Held

Infinity%

QoQ Change in Holders

+14 / -5

Price History

$5.34$9.33$13.32$17.32$21.31Sep 24Jun 25Mar 26

WVE — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
GSK plcNew Position+18.2M+$310.2M
Darwin Global Management, Ltd.New Position+7.3M+$125.2M
PRICE T ROWE ASSOCIATES INC /MD/Increased+3.4M+$95.4M
FEDERATED HERMES, INC.New Position+4.7M+$80.0M
EMERALD ADVISERS, LLCNew Position+2.5M+$41.7M
First Light Asset Management, LLCNew Position+1.9M+$31.5M
EMERALD MUTUAL FUND ADVISERS TRUSTNew Position+1.4M+$24.0M
CITADEL ADVISORS LLCNew Position+790K+$12.0M
VOLORIDGE INVESTMENT MANAGEMENT, LLCNew Position+722K+$12.0M
TANG CAPITAL MANAGEMENT LLCNew Position+600K+$10.2M
EVENTIDE ASSET MANAGEMENT, LLCNew Position+500K+$8.5M
Elmind Capital, LPNew Position+448K+$7.6M
Exome Asset Management LLCNew Position+421K+$7.2M
Universal- Beteiligungs- und Servicegesellschaft mbHNew Position+411K+$7.0M
Trexquant Investment LPNew Position+391K+$6.6M

WVE — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
ADAGE CAPITAL PARTNERS GP, L.L.C.Decreased-4.8M-$106.5B
Kynam Capital Management, LPDecreased-2.4M-$33.3B
683 Capital Management, LLCDecreased-135K-$30.3B
Bellevue Group AGDecreased-2.6M-$29.9B
Siren, L.L.C.Decreased-1.2M-$27.0B
LOOMIS SAYLES & CO L PDecreased-865K-$21.2B
STEMPOINT CAPITAL LPClosed Position-2.1M-$15.4B
MPM BioImpact LLCClosed Position-1.5M-$11.0B
Artisan Partners Limited PartnershipClosed Position-1.2M-$9.0B
Polar Capital Holdings PlcClosed Position-1.1M-$7.8B
Walleye Capital LLCDecreased-352K-$5.3B
UBS Group AGDecreased-437K-$5.2B
BANK OF AMERICA CORP /DE/Decreased-482K-$4.9B
Point72 Asset Management, L.P.Closed Position-664K-$4.9B
JANE STREET GROUP, LLCDecreased-509K-$4.5B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1GSK plc18,245,691$310.2M38.82%Share
2RA CAPITAL MANAGEMENT, L.P.18,203,009$309.5M3.17%Share
3FMR LLC11,991,368$203.0M0.01%Share
4ADAGE CAPITAL PARTNERS GP, L.L.C.9,786,061$166.0M0.25%Share
5MAVERICK CAPITAL LTD9,280,237$157.0M1.69%Share
6Darwin Global Management, Ltd.7,298,421$125.2M2.53%Share
7PRICE T ROWE ASSOCIATES INC /MD/7,258,658$123.0M0.01%Share
8DRIEHAUS CAPITAL MANAGEMENT LLC6,581,067$111.9M0.76%Share
9BlackRock, Inc.5,851,941$99.0M0.00%Share
10M28 Capital Management LP5,664,548$96.3M70.00%Share
11FEDERATED HERMES, INC.4,744,520$80.0M0.13%Share
12BlackRock, Inc.4,165,842$70.0M0.00%Share
13PRIMECAP MANAGEMENT CO/CA/4,095,282$69.6M0.05%Share
14683 Capital Management, LLC4,015,000$68.3M2.97%Share
15STATE STREET CORP2,996,084$50.0M0.00%Share
16GEODE CAPITAL MANAGEMENT, LLC2,735,113$46.0M0.00%Share
17Affinity Asset Advisors, LLC2,700,000$45.9M2.62%Share
18VANGUARD GROUP INC2,568,500$43.7M0.00%Share
19EMERALD ADVISERS, LLC2,455,089$41.7M1.29%Share
20Siren, L.L.C.2,450,000$41.6M1.24%Share
21GOLDMAN SACHS GROUP INC2,332,525$39.0M0.00%Share
22Kynam Capital Management, LP2,169,105$36.9M2.36%Share
23PFIZER INC1,875,000$31.9M13.48%Share
24First Light Asset Management, LLC1,853,851$31.5M2.41%Share
25LOOMIS SAYLES & CO L P1,665,646$28.0M0.03%Share
26FMR LLC1,659,621$28.0M0.00%Share
27Bellevue Group AG1,485,257$25.2M0.48%Share
28FMR LLC1,484,937$25.0M0.00%Share
29EMERALD MUTUAL FUND ADVISERS TRUST1,414,665$24.0M1.17%Share
30RTW INVESTMENTS, LP1,350,000$22.9M0.23%Share
31CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,191,361$20.0M0.00%Share
32BlackRock, Inc.1,036,914$17.0M0.00%Share
33SCHRODER INVESTMENT MANAGEMENT GROUP1,005,984$17.0M0.01%Share
34Squarepoint Ops LLC883,586$15.0M0.02%Share
35NORTHERN TRUST CORP928,195$15.0M0.00%Share
36VANGUARD GROUP INC846,249$14.4M0.00%Share
37Pictet Asset Management Holding SA805,901$13.8M0.01%Share
38CITADEL ADVISORS LLC772,700$13.0M0.00%Call
39SUSQUEHANNA INTERNATIONAL GROUP, LLP785,700$13.0M0.00%Call
40CITADEL ADVISORS LLC792,300$13.0M0.00%Put
41CITADEL ADVISORS LLC763,965$12.0M0.00%Share
42TWO SIGMA INVESTMENTS, LP749,448$12.0M0.02%Share
43VOLORIDGE INVESTMENT MANAGEMENT, LLC722,237$12.0M0.04%Share
44TANG CAPITAL MANAGEMENT LLC600,000$10.2M0.50%Share
45SUSQUEHANNA INTERNATIONAL GROUP, LLP634,100$10.0M0.00%Put
46MILLENNIUM MANAGEMENT LLC584,633$9.0M0.00%Share
47JANE STREET GROUP, LLC574,400$9.0M0.00%Put
48EVENTIDE ASSET MANAGEMENT, LLC500,000$8.5M0.13%Share
49KENNEDY CAPITAL MANAGEMENT LLC492,437$8.4M0.18%Share
50GOLDMAN SACHS GROUP INC521,557$8.0M0.00%Share

WVE Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025217$3.0B+59
Q3 2025158$946.8B+13
Q2 2025145$616.2B-51
Q1 2025196$1.0T+16
Q4 2024180$2.5T+35
Q3 2024145$633.9T+13
Q2 2024132$247.4T+12
Q1 2024120$300.0T—

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As of Q4 2025, 50 institutional investors hold WVE (Wave Life Sciences Ltd.). The largest holder is GSK plc with $310.2M in shares. This quarter, 14 institutions opened new positions and 5 closed their positions.

Frequently Asked Questions

How many hedge funds own WVE?

As of Q4 2025, 50 institutional investors report holding WVE (Wave Life Sciences Ltd.) in their 13F filings.

Who is the largest institutional holder of WVE?

The largest institutional holder of WVE is GSK plc with $310.2M in shares.

Is institutional ownership of WVE increasing or decreasing?

This quarter, 14 institutions opened new positions in WVE and 5 closed their positions.