BAKER BROS. ADVISORS LP Q3 2024 Filing
Filed November 14, 2024
Portfolio Value
$9.6B
Holdings
93
Report Date
Q3 2024
Filing Type
13F-HR
All Holdings (93 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | ONCBeiGene, Ltd. | 10,568,897 | $2.4B | 24.59% | |
| 2 | INCYIncyte Corporation | 30,739,020 | $2.0B | 21.06% | |
| 3 | ACADACADIA Pharmaceuticals Inc. | 42,877,916 | $659.5M | 6.83% | |
| 4 | SMMTSummit Therapeutics Inc. | 24,424,865 | $534.9M | 5.54% | |
| 5 | MDGLMadrigal Pharmaceuticals, Inc. | 1,974,590 | $419.0M | 4.34% | |
| 6 | RVMDRevolution Medicines, Inc. | 7,569,090 | $343.3M | 3.56% | |
| 7 | RYTMRhythm Pharmaceuticals, Inc. | 6,398,366 | $335.2M | 3.47% | |
| 8 | IM8NInsmed Incorporated | 4,415,918 | $322.4M | 3.34% | |
| 9 | KYMRKymera Therapeutics, Inc. | 5,995,929 | $283.8M | 2.94% | |
| 10 | BCYCBicycle Therapeutics plc | 9,399,960 | $212.7M | 2.20% | |
| 11 | EWTXEdgewise Therapeutics, Inc. | 5,840,059 | $155.9M | 1.62% | |
| 12 | REPLReplimune Group, Inc. | 11,045,336 | $121.1M | 1.25% | |
| 13 | ALKSAlkermes plc | 4,181,751 | $117.0M | 1.21% | |
| 14 | DNLIDenali Therapeutics Inc. | 3,731,695 | $108.7M | 1.13% | |
| 15 | INSM 0.75 06/01/28Insmed Incorporated | 42,850,000 | $98.3M | 1.02% | |
| 16 | RAREUltragenyx Pharmaceutical Inc. | 1,576,114 | $87.6M | 0.91% | |
| 17 | NRIXNurix Therapeutics, Inc. | 3,882,125 | $87.2M | 0.90% | |
| 18 | TRDAEntrada Therapeutics, Inc. | 4,865,819 | $77.8M | 0.81% | |
| 19 | IMTXImmatics N.V. | 6,443,398 | $73.5M | 0.76% | |
| 20 | ABCLAbCellera Biologics Inc. | 27,525,640 | $71.6M | 0.74% | |
| 21 | KNSAKiniksa Pharmaceuticals International, plc | 2,818,323 | $70.4M | 0.73% | |
| 22 | 1K0IGM Biosciences, Inc. | 4,092,310 | $67.7M | 0.70% | |
| 23 | ARGXargenx SE | 111,904 | $60.7M | 0.63% | |
| 24 | STOKStoke Therapeutics, Inc. | 4,368,443 | $53.7M | 0.56% | |
| 25 | IMCRImmunocore Holdings plc | 1,515,318 | $47.2M | 0.49% | |
| 26 | KODKodiak Sciences Inc. | 17,310,490 | $45.2M | 0.47% | |
| 27 | SERASera Prognostics, Inc. | 5,434,399 | $42.4M | 0.44% | |
| 28 | CRSPCRISPR Therapeutics AG | 843,075 | $39.6M | 0.41% | |
| 29 | XENEXenon Pharmaceuticals Inc. | 993,679 | $39.1M | 0.41% | |
| 30 | IMVTImmunovant, Inc. | 1,225,410 | $34.9M | 0.36% | |
| 31 | CERSCerus Corporation | 19,477,339 | $33.9M | 0.35% | |
| 32 | IDYAIDEAYA Biosciences, Inc. | 1,062,123 | $33.6M | 0.35% | |
| 33 | ROIVRoivant Sciences Ltd. | 2,798,716 | $32.3M | 0.33% | |
| 34 | AKROAkero Therapeutics, Inc. | 1,097,082 | $31.5M | 0.33% | |
| 35 | KRYSKrystal Biotech, Inc. | 169,934 | $30.9M | 0.32% | |
| 36 | CELCCelcuity Inc. | 1,874,978 | $28.0M | 0.29% | |
| 37 | GLUEMonte Rosa Therapeutics, Inc. | 4,916,095 | $26.1M | 0.27% | |
| 38 | DYNDyne Therapeutics, Inc. | 672,096 | $24.1M | 0.25% | |
| 39 | BMEABiomea Fusion, Inc. | 2,108,949 | $21.3M | 0.22% | |
| 40 | BCAXBicara Therapeutics Inc. | 833,333 | $21.2M | 0.22% | |
| 41 | PRLDPrelude Therapeutics Inc. | 10,123,824 | $21.0M | 0.22% | |
| 42 | CNTACentessa Pharmaceuticals plc | 1,227,178 | $19.6M | 0.20% | |
| 43 | NGNENeurogene Inc. | 456,015 | $19.1M | 0.20% | |
| 44 | PRAXPraxis Precision Medicines, Inc. | 323,105 | $18.6M | 0.19% | |
| 45 | ALMSAlumis Inc. | 1,562,500 | $16.7M | 0.17% | |
| 46 | MRUSMerus N.V. | 300,000 | $15.0M | 0.16% | |
| 47 | TCRXTScan Therapeutics, Inc. | 2,784,792 | $13.9M | 0.14% | |
| 48 | NMRANeumora Therapeutics, Inc. | 1,034,600 | $13.7M | 0.14% | |
| 49 | XNCRXencor, Inc. | 670,431 | $13.5M | 0.14% | |
| 50 | TSVT*2seventy bio, Inc. | 2,497,526 | $11.8M | 0.12% | |
| 51 | FATEFate Therapeutics, Inc. | 2,997,772 | $10.5M | 0.11% | |
| 52 | ARVNArvinas, Inc. | 405,576 | $10.0M | 0.10% | |
| 53 | SANASana Biotechnology, Inc. | 2,380,949 | $9.9M | 0.10% | |
| 54 | DSGNDesign Therapeutics, Inc. | 1,743,725 | $9.4M | 0.10% | |
| 55 | ISIIonis Pharmaceuticals, Inc. | 223,470 | $9.0M | 0.09% | |
| 56 | OPTEYOpthea Limited | 2,173,622 | $8.8M | 0.09% | |
| 57 | TCE2Celldex Therapeutics, Inc. | 247,644 | $8.4M | 0.09% | |
| 58 | RLAYRelay Therapeutics, Inc. | 1,160,117 | $8.2M | 0.09% | |
| 59 | VERVVerve Therapeutics, Inc. | 1,691,530 | $8.2M | 0.08% | |
| 60 | TSHATaysha Gene Therapies, Inc. | 4,004,756 | $8.0M | 0.08% | |
| 61 | MIRMMirum Pharmaceuticals, Inc. | 190,476 | $7.4M | 0.08% | |
| 62 | CTNMContineum Therapeutics, Inc. | 312,500 | $6.0M | 0.06% | |
| 63 | TNGXTango Therapeutics, Inc. | 750,000 | $5.8M | 0.06% | |
| 64 | SKYESkye Bioscience, Inc. | 1,434,634 | $5.6M | 0.06% | |
| 65 | PCVXVaxcyte, Inc. | 48,885 | $5.6M | 0.06% | |
| 66 | CRNXCrinetics Pharmaceuticals, Inc. | 103,927 | $5.3M | 0.06% | |
| 67 | DBVTDBV Technologies S.A. | 7,307,131 | $5.1M | 0.05% | |
| 68 | KALAKALA BIO, Inc. | 891,335 | $5.1M | 0.05% | |
| 69 | GBIOGBXGeneration Bio Co. | 1,944,945 | $4.8M | 0.05% | |
| 70 | ALECAlector, Inc. | 927,264 | $4.3M | 0.04% | |
| 71 | PRMEPrime Medicine, Inc. | 1,028,466 | $4.0M | 0.04% | |
| 72 | SGMTSagimet Biosciences Inc. | 1,381,898 | $3.8M | 0.04% | |
| 73 | GPCRStructure Therapeutics Inc. | 85,500 | $3.8M | 0.04% | |
| 74 | ARCTArcturus Therapeutics Holdings Inc. | 151,329 | $3.5M | 0.04% | |
| 75 | HOOKHOOKIPA Pharma Inc. | 812,814 | $3.5M | 0.04% | |
| 76 | CYPHLeap Therapeutics, Inc. | 1,172,175 | $3.0M | 0.03% | |
| 77 | ELVNEnliven Therapeutics, Inc. | 114,833 | $2.9M | 0.03% | |
| 78 | CMPXCompass Therapeutics, Inc. | 1,557,630 | $2.9M | 0.03% | |
| 79 | WVEWave Life Sciences Ltd. | 344,063 | $2.8M | 0.03% | |
| 80 | —Mersana Therapeutics, Inc. | 1,086,115 | $2.1M | 0.02% | |
| 81 | NAMSNewAmsterdam Pharma Company N.V. | 96,711 | $1.6M | 0.02% | |
| 82 | IPSCCentury Therapeutics, Inc. | 797,460 | $1.4M | 0.01% | |
| 83 | VTVTvTv Therapeutics, Inc. | 97,314 | $1.3M | 0.01% | |
| 84 | AVTEAerovate Therapeutics, Inc. | 628,939 | $1.3M | 0.01% | |
| 85 | PFEPfizer Inc. | 35,000 | $1.0M | 0.01% | |
| 86 | TARAProtara Therapeutics, Inc. | 536,832 | $982K | 0.01% | |
| 87 | ALGSAligos Therapeutics, Inc. | 83,055 | $719K | 0.01% | |
| 88 | BCRXBioCryst Pharmaceuticals, Inc. | 75,778 | $575K | 0.01% | |
| 89 | PMVPPMV Pharmaceuticals, Inc. | 322,024 | $479K | 0.00% | |
| 90 | FHTXFoghorn Therapeutics Inc. | 45,027 | $419K | 0.00% | |
| 91 | ACRVAcrivon Therapeutics, Inc. | 52,885 | $370K | 0.00% | |
| 92 | TYRATyra Biosciences, Inc. | 10,607 | $249K | 0.00% | |
| 93 | SRZNWSurrozen, Inc. | 833,333 | $8K | 0.00% |