Who Owns Prime Medicine, Inc. (PRME)?Hedge Fund & Institutional Holders

$3.67-0.07 (-1.74%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

2.800693286315721e+288%

QoQ Change in Holders

+7 / -7

Price History

$1.15$2.53$3.91$5.29$6.67Sep 24Jun 25Mar 26

PRME — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Sumitomo Mitsui Trust Group, Inc.New Position+3.2M+$11.3B
BALYASNY ASSET MANAGEMENT L.P.Increased+3.1M+$9.7B
UBS Group AGIncreased+2.1M+$6.8B
GOLDMAN SACHS GROUP INCIncreased+1.3M+$2.7B
TWO SIGMA INVESTMENTS, LPIncreased+1.2M+$2.5B
TWO SIGMA ADVISERS, LPNew Position+384K+$1.0B
Point72 Asset Management, L.P.New Position+551K+$1.0B
BANK OF AMERICA CORP /DE/Increased+537K+$999.4M
SUSQUEHANNA INTERNATIONAL GROUP, LLPIncreased+592K+$762.3M
JPMORGAN CHASE & COIncreased+392K+$761.0M
IQ EQ FUND MANAGEMENT (IRELAND) LtdNew Position+179K+$619.0M
Keystone Financial GroupNew Position+130K+$449.0M
GROUP ONE TRADING LLCNew Position+103K+$358.0M
BARCLAYS PLCIncreased+248K+$357.9M
Virtus Investment Advisers, LLCNew Position+65K+$225.0M

PRME — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
FARALLON CAPITAL MANAGEMENT LLCDecreased-3.5M-$22.0B
RA CAPITAL MANAGEMENT, L.P.Closed Position-3.0M-$16.6B
ARK Investment Management LLCDecreased-109K-$11.7B
MWG Management Ltd.Closed Position-1.8M-$9.9B
Amova Asset Management Americas, Inc.Decreased-384K-$8.8B
EcoR1 Capital, LLCClosed Position-1.5M-$8.6B
MILLENNIUM MANAGEMENT LLCDecreased-1.4M-$7.9B
D. E. Shaw & Co., Inc.Decreased-664K-$7.3B
CITADEL ADVISORS LLCDecreased-787K-$5.0B
ADAGE CAPITAL PARTNERS GP, L.L.C.Closed Position-771K-$4.3B
Invesco Ltd.Decreased-705K-$4.0B
Schonfeld Strategic Advisors LLCClosed Position-593K-$3.3B
CHELSEA COUNSEL COClosed Position-208K-$1.2B
Man Group plcClosed Position-190K-$1.1B
TD ASSET MANAGEMENT INCDecreased-87K-$1.0B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Alphabet Inc.16,562,498$57.5B2.23%Share
2ARK Investment Management LLC5,368,526$18.6B0.12%Share
3Sumitomo Mitsui Trust Group, Inc.3,245,506$11.3B0.01%Share
4Amova Asset Management Americas, Inc.3,245,506$11.2B0.13%Share
5Casdin Capital, LLC3,167,175$11.0B0.68%Share
6Woodline Partners LP3,002,844$10.0B0.04%Share
7BALYASNY ASSET MANAGEMENT L.P.3,124,362$10.0B0.01%Share
8UBS Group AG2,425,155$8.4B0.00%Share
9FMR LLC2,167,377$7.0B0.00%Share
10GOLDMAN SACHS GROUP INC1,644,322$5.0B0.00%Share
11TWO SIGMA INVESTMENTS, LP1,629,324$5.0B0.01%Share
12D. E. Shaw & Co., Inc.1,486,552$5.0B0.00%Share
13FARALLON CAPITAL MANAGEMENT LLC1,240,843$4.3B0.02%Share
14SUSQUEHANNA INTERNATIONAL GROUP, LLP1,162,646$4.0B0.00%Share
15CHARLES SCHWAB INVESTMENT MANAGEMENT INC936,815$3.0B0.00%Share
16RENAISSANCE TECHNOLOGIES LLC1,149,159$3.0B0.00%Share
17NORTHERN TRUST CORP769,229$2.0B0.00%Share
18MOORE CAPITAL MANAGEMENT, LP500,000$1.7B0.02%Share
19Point72 Asset Management, L.P.551,030$1.0B0.00%Share
20BARCLAYS PLC363,826$1.0B0.00%Share
21AQR CAPITAL MANAGEMENT LLC400,496$1.0B0.00%Share
22JPMORGAN CHASE & CO380,389$1.0B0.00%Share
23BANK OF AMERICA CORP /DE/571,293$1.0B0.00%Share
24TWO SIGMA ADVISERS, LP383,500$1.0B0.00%Share
25SUSQUEHANNA INTERNATIONAL GROUP, LLP471,700$1.0B0.00%Put
26IQ EQ FUND MANAGEMENT (IRELAND) Ltd178,519$619.0M0.04%Share
27GROUP ONE TRADING LLC154,700$536.0M0.00%Call
28Keystone Financial Group129,665$449.0M0.03%Share
29GROUP ONE TRADING LLC103,213$358.0M0.00%Share
30Palumbo Wealth Management LLC85,539$296.0M0.07%Share
31GROUP ONE TRADING LLC77,200$267.0M0.00%Put
32Virtus Investment Advisers, LLC64,886$225.0M0.06%Share
33Mutual Advisors, LLC45,200$156.0M0.00%Share
34Elevate Capital Advisors, LLC42,666$148.0M0.10%Share
35IvyRock Asset Management (HK) Ltd41,800$145.0M0.08%Share
36CENTRAL TRUST Co34,995$121.0M0.00%Share
37AXQ CAPITAL, LP33,405$115.0M0.03%Share
38Invesco Ltd.29,529$102.0M0.00%Share
39TRANSCEND CAPITAL ADVISORS, LLC26,500$91.0M0.01%Share
40Arizona State Retirement System24,085$83.0M0.00%Share
41THOMPSON DAVIS & CO., INC.22,740$78.0M0.05%Share
42Scientech Research LLC22,393$77.0M0.05%Share
43SHELTON WEALTH MANAGEMENT, LLC20,066$69.0M0.03%Share
44KLP KAPITALFORVALTNING AS18,500$64.0M0.00%Share
45Invesco Ltd.17,586$61.0M0.00%Share
46Clarius Group, LLC16,080$55.0M0.00%Share
47LEVIN CAPITAL STRATEGIES, L.P.15,000$52.0M0.00%Share
48OPPENHEIMER & CO INC12,433$43.0M0.00%Share
49UBS Group AG12,509$43.0M0.00%Share
50TEACHER RETIREMENT SYSTEM OF TEXAS12,235$42.0M0.00%Share

PRME Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025180$187.8B+46
Q3 2025134$327.7B+26
Q2 2025108$92.0B-15
Q1 2025123$87.7B-4
Q4 2024127$127.3B+26
Q3 2024101$1.2T-1
Q2 2024102$2.4T+8
Q1 202494$153.6T—

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As of Q4 2025, 50 institutional investors hold PRME (Prime Medicine, Inc.). The largest holder is Alphabet Inc. with $57.5B in shares. This quarter, 7 institutions opened new positions and 7 closed their positions.

Frequently Asked Questions

How many hedge funds own PRME?

As of Q4 2025, 50 institutional investors report holding PRME (Prime Medicine, Inc.) in their 13F filings.

Who is the largest institutional holder of PRME?

The largest institutional holder of PRME is Alphabet Inc. with $57.5B in shares.

Is institutional ownership of PRME increasing or decreasing?

This quarter, 7 institutions opened new positions in PRME and 7 closed their positions.