Who Owns Alkermes plc (ALKS)?Hedge Fund & Institutional Holders

$28.04+0.28 (+1.01%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

Infinity%

QoQ Change in Holders

+5 / -6

Price History

$25.70$28.27$30.85$33.42$36.00Sep 24Jun 25Mar 26

ALKS — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Entropy Technologies, LPIncreased+40K+$1000.0B
WELLINGTON MANAGEMENT GROUP LLPIncreased+2.6M+$70.7B
UBS Group AGIncreased+1.8M+$48.6B
BAKER BROS. ADVISORS LPIncreased+1.9M+$37.4B
Soleus Capital Management, L.P.New Position+1.3M+$37.0B
FMR LLCIncreased+60K+$36.0B
AMERICAN CENTURY COMPANIES INCIncreased+1.6M+$34.1B
BANK OF AMERICA CORP /DE/Increased+237K+$34.0B
VIRGINIA RETIREMENT SYSTEMS ET AlNew Position+976K+$27.3B
PRINCIPAL FINANCIAL GROUP INCNew Position+948K+$26.5B
JPMORGAN CHASE & COIncreased+1.3M+$26.2B
BALYASNY ASSET MANAGEMENT L.P.New Position+680K+$19.0B
TWO SIGMA INVESTMENTS, LPIncreased+557K+$13.3B
CITADEL ADVISORS LLCIncreased+493K+$10.9B
RICE HALL JAMES & ASSOCIATES, LLCNew Position+379K+$10.6B

ALKS — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Holocene Advisors, LPClosed Position-2.5M-$74.1B
Paradigm Biocapital Advisors LPClosed Position-1.7M-$51.6B
Avoro Capital Advisors LLCDecreased-840K-$28.0B
Artisan Partners Limited PartnershipDecreased-761K-$26.3B
Pacer Advisors, Inc.Closed Position-808K-$24.2B
Man Group plcDecreased-585K-$18.9B
Sio Capital Management, LLCDecreased-579K-$17.6B
EcoR1 Capital, LLCClosed Position-500K-$15.0B
Glenmede Investment Management, LPClosed Position-456K-$13.7B
JANE STREET GROUP, LLCDecreased-331K-$11.8B
MACKENZIE FINANCIAL CORPDecreased-347K-$11.3B
MACQUARIE GROUP LTDClosed Position-373K-$11.2B
PRIMECAP MANAGEMENT CO/CA/Decreased-195K-$11.0B
NORTHERN TRUST CORPDecreased-113K-$10.0B
Affinity Asset Advisors, LLCDecreased-250K-$9.5B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Entropy Technologies, LP63,724$1.0T54.26%Share
2BAKER BROS. ADVISORS LP10,012,267$280.1B1640.31%Share
3RENAISSANCE TECHNOLOGIES LLC6,668,028$186.0B288.55%Share
4AMERICAN CENTURY COMPANIES INC5,956,824$166.0B83.43%Share
5JPMORGAN CHASE & CO4,826,164$135.0B8.48%Share
6DIMENSIONAL FUND ADVISORS LP4,014,006$112.0B23.49%Share
7Commodore Capital LP3,550,000$99.3B6.61%Share
8PRIMECAP MANAGEMENT CO/CA/2,564,300$71.7B54.31%Share
9UBS Group AG2,356,251$65.9B10.69%Share
10CHARLES SCHWAB INVESTMENT MANAGEMENT INC2,152,756$60.0B9.32%Share
11WELLINGTON MANAGEMENT GROUP LLP1,910,316$53.0B9.29%Share
12FIRST TRUST ADVISORS LP1,454,002$40.0B29.07%Share
13ARROWSTREET CAPITAL, LIMITED PARTNERSHIP1,450,841$40.0B23.43%Share
14Avoro Capital Advisors LLC1,400,000$39.2B385.01%Share
15NORTHERN TRUST CORP1,411,922$39.0B4.97%Share
16LOOMIS SAYLES & CO L P1,413,457$39.0B47.02%Share
17Artisan Partners Limited Partnership1,349,122$37.0B55.40%Share
18Soleus Capital Management, L.P.1,322,364$37.0B1.36%Share
19GOLDMAN SACHS GROUP INC1,193,769$33.0B4.07%Share
20TWO SIGMA INVESTMENTS, LP1,213,397$33.0B46.55%Share
21Nuveen, LLC1,087,046$30.0B7.86%Share
22GOLDMAN SACHS GROUP INC1,065,316$29.0B3.58%Share
23CITADEL ADVISORS LLC1,061,270$29.0B4.36%Share
24Affinity Asset Advisors, LLC1,000,000$28.0B1.59%Share
25VIRGINIA RETIREMENT SYSTEMS ET Al976,483$27.3B162.55%Share
26BANK OF AMERICA CORP /DE/996,553$27.0B1.96%Share
27PRINCIPAL FINANCIAL GROUP INC938,690$26.3B13.41%Share
28PANAGORA ASSET MANAGEMENT INC928,964$25.0B88.60%Share
29DRIEHAUS CAPITAL MANAGEMENT LLC796,968$22.3B151.47%Share
30D. E. Shaw & Co., Inc.813,428$22.0B12.06%Share
31Nuveen, LLC738,824$20.0B5.24%Share
32Frazier Life Sciences Management, L.P.700,647$19.6B0.53%Share
33BALYASNY ASSET MANAGEMENT L.P.679,633$19.0B24.12%Share
34WELLINGTON MANAGEMENT GROUP LLP680,138$19.0B3.33%Share
35PUBLIC SECTOR PENSION INVESTMENT BOARD671,170$18.0B60.44%Share
36SEGALL BRYANT & HAMILL, LLC615,292$17.2B233.01%Share
37FMR LLC637,910$17.0B0.87%Share
38Nuveen, LLC601,158$16.0B4.19%Share
39BARCLAYS PLC563,557$15.0B3.60%Share
40Woodline Partners LP558,567$15.0B58.12%Share
41TWO SIGMA ADVISERS, LP562,587$15.0B29.16%Share
42AMERIPRISE FINANCIAL INC527,195$14.0B3.16%Share
43AQR CAPITAL MANAGEMENT LLC511,274$14.0B7.34%Share
44MetLife Investment Management, LLC530,379$14.0B67.73%Share
45LOOMIS SAYLES & CO L P489,065$13.0B15.67%Share
46FMR LLC477,631$13.0B0.66%Share
47RHUMBLINE ADVISERS439,195$12.0B9.70%Share
48VICTORY CAPITAL MANAGEMENT INC402,578$11.0B6.21%Share
49BALYASNY ASSET MANAGEMENT L.P.419,700$11.0B13.96%Put
50RICE HALL JAMES & ASSOCIATES, LLC379,458$10.6B0.58%Share

ALKS Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025361$3.5T+94
Q3 2025267$2.5T-30
Q2 2025297$2.1T-69
Q1 2025366$3.9T+47
Q4 2024319$5.2T+43
Q3 2024276$193.6T+15
Q2 2024261$217.7T-1
Q1 2024262$1124.4T—

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As of Q4 2025, 50 institutional investors hold ALKS (Alkermes plc). The largest holder is Entropy Technologies, LP with $1.0T in shares. This quarter, 5 institutions opened new positions and 6 closed their positions.

Frequently Asked Questions

How many hedge funds own ALKS?

As of Q4 2025, 50 institutional investors report holding ALKS (Alkermes plc) in their 13F filings.

Who is the largest institutional holder of ALKS?

The largest institutional holder of ALKS is Entropy Technologies, LP with $1.0T in shares.

Is institutional ownership of ALKS increasing or decreasing?

This quarter, 5 institutions opened new positions in ALKS and 6 closed their positions.