Who Owns CRISPR Therapeutics AG (CRSP)?Hedge Fund & Institutional Holders

$48.62-0.25 (-0.52%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

Infinity%

QoQ Change in Holders

+12 / -2

Price History

$31.27$42.65$54.03$65.40$76.78Aug 24Jun 25Mar 26

CRSP — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Sumitomo Mitsui Trust Group, Inc.New Position+2.0M+$102.7B
FMR LLCIncreased+68K+$101.9B
IQ EQ FUND MANAGEMENT (IRELAND) LtdNew Position+390K+$20.4B
No Street GP LPNew Position+125K+$6.6B
Neo Ivy Capital ManagementNew Position+79K+$4.1B
COMMONWEALTH EQUITY SERVICES, LLCNew Position+78K+$4.0B
NWAM LLCNew Position+62K+$3.4B
CITADEL ADVISORS LLCIncreased+101K+$3.2B
JONES FINANCIAL COMPANIES LLLPNew Position+57K+$3.0B
Privium Fund Management B.V.New Position+43K+$2.2B
CITIGROUP INCIncreased+72K+$2.1B
FIRST TRUST ADVISORS LPNew Position+54K+$2.0B
Qsemble Capital Management, LPNew Position+41K+$2.0B
Bouvel Investment Partners, LLCNew Position+32K+$1.7B
Hennion & Walsh Asset Management, Inc.New Position+28K+$1.5B

CRSP — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
TWO SIGMA INVESTMENTS, LPDecreased-574K-$43.7B
Amova Asset Management Americas, Inc.Decreased-206K-$37.6B
TWO SIGMA ADVISERS, LPDecreased-411K-$29.1B
ROYAL BANK OF CANADADecreased-301K-$22.2B
LPL Financial LLCDecreased-40K-$13.7B
NORTHERN TRUST CORPDecreased-25K-$13.5B
JPMORGAN CHASE & CODecreased-50K-$13.5B
LOOMIS SAYLES & CO L PDecreased-10K-$13.0B
BANK OF MONTREAL /CAN/Decreased-177K-$12.1B
BARCLAYS PLCDecreased-100K-$10.7B
Contrarius Group Holdings LtdDecreased-114K-$9.3B
Woodline Partners LPClosed Position-144K-$9.3B
TANG CAPITAL MANAGEMENT LLCClosed Position-100K-$6.5B
Capital International SarlDecreased-5K-$6.5B
EverSource Wealth Advisors, LLCDecreased-40K-$6.3B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1ARK Investment Management LLC10,522,057$551.8B3.66%Share
2Orbis Allan Gray Ltd5,934,328$311.0B1.30%Share
3SR ONE CAPITAL MANAGEMENT, LP2,038,763$106.9B15.14%Share
4Sumitomo Mitsui Trust Group, Inc.1,958,111$102.7B0.06%Share
5Amova Asset Management Americas, Inc.1,958,111$102.6B1.19%Share
6UBS Group AG1,945,519$102.0B0.02%Share
7EcoR1 Capital, LLC1,389,276$72.9B3.31%Share
8NEA Management Company, LLC1,058,570$55.5B2.83%Share
9CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,030,182$54.0B0.01%Share
10FMR LLC1,032,386$54.0B0.00%Share
11FMR LLC917,305$48.0B0.00%Share
12LOOMIS SAYLES & CO L P870,345$45.0B0.05%Share
13SUSQUEHANNA INTERNATIONAL GROUP, LLP853,971$44.0B0.01%Share
14DIMENSIONAL FUND ADVISORS LP805,368$42.0B0.01%Share
15CITADEL ADVISORS LLC758,200$39.0B0.01%Put
16SUSQUEHANNA INTERNATIONAL GROUP, LLP693,900$36.0B0.00%Put
17NORTHERN TRUST CORP688,478$36.0B0.00%Share
18CITADEL ADVISORS LLC578,700$30.0B0.00%Call
19BANK OF AMERICA CORP /DE/587,236$30.0B0.00%Share
20SUSQUEHANNA INTERNATIONAL GROUP, LLP550,400$28.0B0.00%Call
21UBS Group AG526,243$27.6B0.00%Share
22IMC-Chicago, LLC479,900$25.2B0.01%Call
23TWO SIGMA INVESTMENTS, LP470,621$24.0B0.03%Share
24Caption Management, LLC457,100$24.0B0.16%Call
25IQ EQ FUND MANAGEMENT (IRELAND) Ltd389,519$20.4B1.41%Share
26D. E. Shaw & Co., Inc.381,100$19.0B0.01%Call
27BANK OF AMERICA CORP /DE/377,325$19.0B0.00%Share
28GROUP ONE TRADING LLC332,900$17.5B0.03%Call
29AMERIPRISE FINANCIAL INC295,027$15.0B0.00%Share
30CITADEL ADVISORS LLC267,685$14.0B0.00%Share
31PEAK6 LLC274,500$14.0B0.03%Put
32JPMORGAN CHASE & CO259,337$13.0B0.00%Share
33BARCLAYS PLC228,405$11.0B0.00%Share
34IMC-Chicago, LLC198,000$10.4B0.00%Put
35JPMORGAN CHASE & CO204,566$10.0B0.00%Share
36Nuveen, LLC174,918$9.0B0.00%Share
37GOLDMAN SACHS GROUP INC175,188$9.0B0.00%Share
38SIMPLEX TRADING, LLC181,200$9.0B0.01%Call
39Contrarius Group Holdings Ltd156,605$8.2B0.40%Share
40GROUP ONE TRADING LLC155,100$8.1B0.01%Put
41TD ASSET MANAGEMENT INC158,416$8.0B0.01%Share
42WELLS FARGO & COMPANY/MN165,911$8.0B0.00%Share
43TWO SIGMA ADVISERS, LP162,400$8.0B0.02%Share
44Swiss National Bank161,500$8.0B0.00%Share
45SIMPLEX TRADING, LLC141,300$7.0B0.00%Put
46ROYAL BANK OF CANADA138,713$7.0B0.00%Share
47No Street GP LP125,000$6.6B0.44%Share
48Marex Group plc127,544$6.0B0.04%Share
49RHUMBLINE ADVISERS118,778$6.0B0.00%Share
50CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM116,104$6.0B0.00%Share

CRSP Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025473$2.2T+184
Q3 2025289$2.8T-93
Q2 2025382$2.0T-3
Q1 2025385$1.7T+34
Q4 2024351$4.1T+48
Q3 2024303$433.5T-22
Q2 2024325$541.4T-19
Q1 2024344$575.1T—

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As of Q4 2025, 50 institutional investors hold CRSP (CRISPR Therapeutics AG). The largest holder is ARK Investment Management LLC with $551.8B in shares. This quarter, 12 institutions opened new positions and 2 closed their positions.

Frequently Asked Questions

How many hedge funds own CRSP?

As of Q4 2025, 50 institutional investors report holding CRSP (CRISPR Therapeutics AG) in their 13F filings.

Who is the largest institutional holder of CRSP?

The largest institutional holder of CRSP is ARK Investment Management LLC with $551.8B in shares.

Is institutional ownership of CRSP increasing or decreasing?

This quarter, 12 institutions opened new positions in CRSP and 2 closed their positions.