Boxer Capital Management, LLC Q4 2024 Filing

Filed February 14, 2025

Portfolio Value

$1.2T

Holdings

60

Report Date

Q4 2024

Filing Type

13F-HR

All Holdings (60 positions)

#StockSharesValue% PortfolioType
1
RVMDRevolution Medicines Inc
4,279,464$187.2B15.94%
2
SWTXSpringworks Therapeutics Inc
3,421,541$123.6B10.53%
3
NUVLNuvalent Inc
1,120,192$87.7B7.47%
4
MRUSMerus N V
1,900,000$79.9B6.80%
5
RNAAvidity Biosciences Inc
1,727,388$50.2B4.28%
6
APLSApellis Pharmaceuticals Inc
1,426,000$45.5B3.87%
7
AXSMAxsome Therapeutics Inc
470,000$39.8B3.39%
8
SRRKScholar Rock Hldg Corp
750,000$32.4B2.76%
9
TNGXTango Therapeutics Inc
10,380,999$32.1B2.73%
10
TYRATyra Biosciences Inc
2,027,678$28.2B2.40%
11
RCUSArcus Biosciences Inc
1,602,200$23.9B2.03%
12
XENEXenon Pharmaceuticals Inc
600,000$23.5B2.00%
13
LEGNLegend Biotech Corp
700,000$22.8B1.94%
14
REPLReplimune Group Inc
1,796,341$21.8B1.85%
15
GONGeron Corp
6,000,000$21.2B1.81%
16
THRDThird Harmonic Bio Inc
2,000,000$20.6B1.75%
17
IMVTImmunovant Inc
825,000$20.4B1.74%
18
ARVNArvinas Inc
1,058,614$20.3B1.73%
19
PSTXUSDPoseida Therapeutics Inc
2,000,000$19.2B1.63%
20
RCKTRocket Pharmaceuticals Inc
1,466,051$18.4B1.57%
21
ANABAnaptys Bio Inc
1,300,000$17.2B1.47%
22
KYMRKymera Therapeutics Inc
425,000$17.1B1.46%
23
ELVNEnliven Therapeutics Inc
671,358$15.1B1.29%
24
DAWNDay One Biopharmaceuticals I
1,189,943$15.1B1.28%
25
ORICOric Pharmaceuticals Inc
1,732,571$14.0B1.19%
26
GPCRStructure Therapeutics Inc
500,000$13.6B1.15%
27
KALVKalvista Pharmaceuticals Inc
1,590,000$13.5B1.15%
28
QUREUniqure NV
750,000$13.2B1.13%
29
CGEMCullinan Therapeutics Inc
907,895$11.1B0.94%
30
SYRESpyre Therapeutics Inc
466,680$10.9B0.93%
31
NRIXNurix Therapeutics Inc
563,067$10.6B0.90%
32
KODKodiak Sciences Inc
1,000,000$9.9B0.85%
33
PRTAProthena Corp PLC
690,000$9.6B0.81%
34
JSPRJasper Therapeutics Inc
350,000$7.5B0.64%
35
5E7iTeos Therapeutics Inc
946,915$7.3B0.62%
36
CMRXEURChimerix Inc
2,060,000$7.2B0.61%
37
TILInstil Bio Inc
355,500$6.8B0.58%
38
AMLXAmylyx Pharmaceuticals Inc
1,750,000$6.6B0.56%
39
IOVAIovance Biotherapeutics Inc
750,000$5.5B0.47%
40
CLYMClimb Bio Inc
2,603,190$4.7B0.40%
41
SMMTSummit Therapeutics Inc
250,000$4.5B0.38%
42
TERNTerns Pharmaceuticals Inc
752,000$4.2B0.35%
43
KROSKeros Therapeutics Inc
250,000$4.0B0.34%
44
APGEApogee Therapeutics Inc
86,000$3.9B0.33%
45
OLMAOlema Pharmaceuticals Inc
650,000$3.8B0.32%
46
Mersana Therapeutics Inc
2,635,000$3.8B0.32%
47
SANASana Biotechnology Inc
1,545,000$2.5B0.21%
48
BCAXBicara Therapeutics Inc
135,000$2.4B0.20%
49
RLAYRelay Therapeutics Inc
536,132$2.2B0.19%
50
PRLDPrelude Therapeutics Inc
1,708,187$2.2B0.19%
51
ZNTLZentalis Pharmaceuticals Inc
450,000$1.4B0.12%
52
BDTXBlack Diamond Therapeutics I
506,000$1.1B0.09%
53
OBIOOrchestra Biomed Hldgs Inc
238,193$952.8M0.08%
54
ZURAZura Bio Ltd
300,000$750.0M0.06%
55
MISTMilestone Pharmaceuticals In
309,007$729.3M0.06%
56
BOLDBoundless Bio Inc
250,000$725.0M0.06%
57
BCABBioAtla Inc
686,347$405.8M0.03%
58
DBVTDBV Technologies S A
50,000$154.5M0.01%
59
NUVB/WSNuvation Bio Inc
266,666$61.3M0.01%
60
SRZNWSurrozen Inc
66,666$1.7M0.00%