Who Owns AnaptysBio, Inc. (ANAB)?Hedge Fund & Institutional Holders

$64.72-0.09 (-0.14%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

2.943121493101268e+279%

QoQ Change in Holders

+6 / -9

Price History

$12.38$25.48$38.59$51.70$64.81Sep 24Jun 25Mar 26

ANAB — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
SanofiNew Position+822K+$39.8B
Affinity Asset Advisors, LLCNew Position+445K+$21.6B
D. E. Shaw & Co., Inc.Increased+321K+$21.3B
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPIncreased+189K+$15.7B
683 Capital Management, LLCIncreased+101K+$14.7B
FEDERATED HERMES, INC.New Position+299K+$14.0B
GOLDMAN SACHS GROUP INCIncreased+69K+$8.9B
Sofinnova Investments, Inc.Increased+33K+$6.2B
Eversept Partners, LPNew Position+121K+$5.9B
Connor, Clark & Lunn Investment Management Ltd.New Position+122K+$5.0B
BANK OF AMERICA CORP /DE/Increased+4K+$5.0B
Invesco Ltd.Increased+82K+$4.7B
HighMark Wealth Management LLCNew Position+94K+$4.6B
TWO SIGMA INVESTMENTS, LPIncreased+215+$4.1B
CITADEL ADVISORS LLCIncreased+83K+$3.2B

ANAB — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Assenagon Asset Management S.A.Closed Position-840K-$25.7B
Soleus Capital Management, L.P.Decreased-491K-$12.6B
FRANKLIN RESOURCES INCClosed Position-47K-$11.6B
JACOBS LEVY EQUITY MANAGEMENT, INCDecreased-323K-$9.6B
MILLENNIUM MANAGEMENT LLCDecreased-706K-$7.5B
SECTORAL ASSET MANAGEMENT INCClosed Position-194K-$6.0B
JANE STREET GROUP, LLCDecreased-97K-$5.5B
Skandinaviska Enskilda Banken AB (publ)Closed Position-145K-$4.4B
SUSQUEHANNA INTERNATIONAL GROUP, LLPClosed Position-145K-$4.4B
Trexquant Investment LPDecreased-53K-$3.4B
MACQUARIE GROUP LTDClosed Position-94K-$2.9B
Walleye Capital LLCClosed Position-56K-$1.7B
MARSHALL WACE, LLPClosed Position-54K-$1.7B
Ikarian Capital, LLCClosed Position-48K-$1.5B
VICTORY CAPITAL MANAGEMENT INCDecreased-93K-$1.2B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1EcoR1 Capital, LLC7,880,094$382.0B17.33%Share
2Point72 Asset Management, L.P.1,932,890$93.0B104.00%Share
3TANG CAPITAL MANAGEMENT LLC1,332,087$64.6B3.19%Share
4Sanofi821,917$39.8B12.84%Share
5MILLENNIUM MANAGEMENT LLC813,571$39.0B16.40%Share
6683 Capital Management, LLC648,093$31.4B1.37%Share
7First Light Asset Management, LLC646,238$31.3B2.40%Share
8ARROWSTREET CAPITAL, LIMITED PARTNERSHIP559,744$27.0B15.81%Share
9Woodline Partners LP501,023$24.0B92.99%Share
10D. E. Shaw & Co., Inc.475,695$23.0B12.61%Share
11Affinity Asset Advisors, LLC444,692$21.6B1.23%Share
12TWO SIGMA ADVISERS, LP356,700$17.0B33.05%Share
13Nuveen, LLC313,844$15.0B3.93%Share
14SUSQUEHANNA INTERNATIONAL GROUP, LLP304,500$14.0B1.61%Put
15FEDERATED HERMES, INC.290,386$14.0B23.39%Share
16Sofinnova Investments, Inc.287,690$13.9B0.60%Share
17GOLDMAN SACHS GROUP INC272,747$13.0B1.60%Share
18TWO SIGMA INVESTMENTS, LP256,635$12.0B16.93%Share
19Ensign Peak Advisors, Inc215,454$10.0B17.66%Share
20Caption Management, LLC200,000$9.7B66.49%Call
21CHARLES SCHWAB INVESTMENT MANAGEMENT INC198,660$9.0B1.40%Share
22D. E. Shaw & Co., Inc.194,593$9.0B4.93%Share
23NORTHERN TRUST CORP163,680$7.0B0.89%Share
24GROUP ONE TRADING LLC136,600$6.6B11.56%Call
25Soleus Capital Management, L.P.135,000$6.5B0.24%Share
26Granahan Investment Management, LLC125,855$6.1B0.26%Share
27GOLDMAN SACHS GROUP INC126,167$6.0B0.74%Share
28Eversept Partners, LP120,927$5.9B0.30%Share
29Invesco Ltd.113,360$5.5B0.84%Share
30Connor, Clark & Lunn Investment Management Ltd.122,476$5.0B13.11%Share
31VICTORY CAPITAL MANAGEMENT INC110,583$5.0B2.82%Share
32Jump Financial, LLC119,600$5.0B61.43%Share
33HighMark Wealth Management LLC94,050$4.6B1.86%Share
34BANK OF AMERICA CORP /DE/90,541$4.0B0.29%Share
35ExodusPoint Capital Management, LP83,313$4.0B31.38%Share
36UBS Group AG68,091$3.3B0.54%Share
37CITIGROUP INC73,035$3.0B1.32%Share
38RENAISSANCE TECHNOLOGIES LLC76,300$3.0B4.65%Share
39CITADEL ADVISORS LLC69,203$3.0B0.45%Share
40PDT Partners, LLC43,001$2.1B0.14%Share
41Fisher Asset Management, LLC56,564$2.0B0.68%Share
42BARCLAYS PLC59,642$2.0B0.48%Share
43JACOBS LEVY EQUITY MANAGEMENT, INC55,088$2.0B7.72%Share
44DCF Advisers, LLC35,250$1.7B0.46%Share
45TEMA ETFS LLC22,560$1.1B0.08%Share
46CITADEL ADVISORS LLC40,280$1.0B0.15%Share
47CITADEL ADVISORS LLC25,200$1.0B0.15%Call
48CITADEL ADVISORS LLC30,400$1.0B0.15%Put
49WELLINGTON MANAGEMENT GROUP LLP41,001$1.0B0.18%Share
50NEOS Investment Management LLC22,895$1.0B5.79%Share

ANAB Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025177$998.1B+44
Q3 2025133$725.0B+5
Q2 2025128$606.3B-25
Q1 2025153$621.2B+19
Q4 2024134$317.7B+2
Q3 2024132$7.7T+18
Q2 2024114$6.5T+1
Q1 2024113$218.7T—

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As of Q4 2025, 50 institutional investors hold ANAB (AnaptysBio, Inc.). The largest holder is EcoR1 Capital, LLC with $382.0B in shares. This quarter, 6 institutions opened new positions and 9 closed their positions.

Frequently Asked Questions

How many hedge funds own ANAB?

As of Q4 2025, 50 institutional investors report holding ANAB (AnaptysBio, Inc.) in their 13F filings.

Who is the largest institutional holder of ANAB?

The largest institutional holder of ANAB is EcoR1 Capital, LLC with $382.0B in shares.

Is institutional ownership of ANAB increasing or decreasing?

This quarter, 6 institutions opened new positions in ANAB and 9 closed their positions.