Who Owns Zentalis Pharmaceuticals, Inc. (ZNTL)?Hedge Fund & Institutional Holders

$2.69-0.06 (-2.18%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$5.32900030000002e+202T

% of Float Held

7.963314231464127e+279%

QoQ Change in Holders

+6 / -4

Price History

$1.04$1.87$2.70$3.53$4.36Sep 24Jun 25Mar 26

ZNTL — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
5AM Venture Management, LLCIncreased+3.5M+$4.6B
Connor, Clark & Lunn Investment Management Ltd.Increased+406K+$425.0M
Anfield Capital Management, LLCIncreased+171K+$219.2M
UBS Group AGIncreased+142K+$105.7M
Universal- Beteiligungs- und Servicegesellschaft mbHNew Position+51K+$68.0M
49 WEALTH MANAGEMENT, LLCIncreased+43K+$52.4M
ADAR1 Capital Management, LLCIncreased+30K+$32.5M
Carson Advisory Inc.New Position+23K+$31.0M
Acorn Wealth Advisors, LLCNew Position+20K+$27.0M
EVERGREEN CAPITAL MANAGEMENT LLCNew Position+17K+$22.0M
BARR E S & COIncreased+18K+$16.6M
Shay Capital LLCNew Position+11K+$14.0M
Quarry LPIncreased+23K+$13.8M
Ishara Investments LPNew Position+1.3M+$1.8M
Opaleye Management Inc.Increased+1.1M+$1.4M

ZNTL — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Matrix Capital Management Company, LPClosed Position-14.0M-$21.1B
TANG CAPITAL MANAGEMENT LLCClosed Position-1.6M-$2.3B
BALYASNY ASSET MANAGEMENT L.P.Closed Position-1.2M-$1.8B
TYBOURNE CAPITAL MANAGEMENT (HK) LTDClosed Position-961K-$1.5B
MILLENNIUM MANAGEMENT LLCDecreased-229K-$1.4B
CITADEL ADVISORS LLCDecreased-113K-$1.1B
JPMORGAN CHASE & CODecreased-538K-$1.1B
JACOBS LEVY EQUITY MANAGEMENT, INCDecreased-576K-$1.1B
JANE STREET GROUP, LLCDecreased-172K-$974.9M
Peapod Lane Capital LLCDecreased-117K-$853.3M
GOLDMAN SACHS GROUP INCDecreased-227K-$521.2M
SUSQUEHANNA INTERNATIONAL GROUP, LLPDecreased-191K-$303.7M
DIMENSIONAL FUND ADVISORS LPDecreased-89K-$279.4M
Graham Capital Management, L.P.Decreased-61K-$229.7M
Walleye Capital LLCDecreased-10K-$181.9M

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
15AM Venture Management, LLC3,947,913$5.3B1.68%Share
2RENAISSANCE TECHNOLOGIES LLC2,883,745$3.0B0.00%Share
3TWO SIGMA ADVISERS, LP1,483,500$2.0B0.00%Share
4CITADEL ADVISORS LLC1,676,520$2.0B0.00%Share
5D. E. Shaw & Co., Inc.1,550,043$2.0B0.00%Share
6Decheng Capital LLC1,323,327$1.8B0.24%Share
7PRIMECAP MANAGEMENT CO/CA/957,420$1.3B0.00%Share
8PFIZER INC953,834$1.3B0.54%Share
9Connor, Clark & Lunn Investment Management Ltd.787,055$1.0B0.00%Share
10TWO SIGMA INVESTMENTS, LP1,471,414$1.0B0.00%Share
11BANK OF AMERICA CORP /DE/1,250,931$1.0B0.00%Share
12UBS Group AG674,492$910.0M0.00%Share
13Stonepine Capital Management, LLC463,700$625.0M0.46%Share
14Anfield Capital Management, LLC242,605$327.0M0.10%Share
15Invesco Ltd.188,582$254.0M0.00%Share
16Quarry LP132,000$178.0M0.03%Share
17ADAR1 Capital Management, LLC80,000$108.0M0.01%Share
1849 WEALTH MANAGEMENT, LLC70,911$95.0M0.01%Share
19BARR E S & CO57,500$77.0M0.00%Share
20Universal- Beteiligungs- und Servicegesellschaft mbH51,061$68.0M0.00%Share
21Carson Advisory Inc.23,470$31.0M0.02%Share
22Acorn Wealth Advisors, LLC20,000$27.0M0.01%Share
23GROUP ONE TRADING LLC20,100$27.0M0.00%Call
24Birchview Capital, LP17,000$22.0M0.01%Share
25EVERGREEN CAPITAL MANAGEMENT LLC16,915$22.0M0.00%Share
26Shay Capital LLC10,662$14.0M0.00%Share
27HIGHLINE WEALTH PARTNERS LLC5,000$6.0M0.00%Share
28VANGUARD GROUP INC2,550,496$3.0M0.00%Share
29ACADIAN ASSET MANAGEMENT LLC2,849,294$3.0M0.00%Share
30Opaleye Management Inc.1,400,906$1.9M0.25%Share
31Ishara Investments LP1,320,000$1.8M2.04%Share
32GSA CAPITAL PARTNERS LLP1,169,573$1.0M0.09%Share
33BlackRock, Inc.1,000,136$1.0M0.00%Share
34Almitas Capital LLC610,073$823K0.18%Share
35Peapod Lane Capital LLC448,861$605K0.51%Share
36WEALTH ENHANCEMENT ADVISORY SERVICES, LLC130,407$232K0.00%Share
37OPAL CAPITAL LLC72,251$173K0.04%Share
38CWM, LLC8,564$12K0.00%Share
39EverSource Wealth Advisors, LLC1,644$2K0.00%Share
40BlackRock, Inc.93,001$00.00%Share
41BlackRock, Inc.12,682$00.00%Share
42BlackRock, Inc.144,149$00.00%Share
43MORGAN STANLEY66,941$00.00%Share
44BNP PARIBAS FINANCIAL MARKETS419,367$00.00%Share
45IEQ CAPITAL, LLC12,229$00.00%Share
46Walleye Capital LLC110,448$00.00%Share
47Inspire Investing, LLC16$00.00%Share
48Squarepoint Ops LLC107,734$00.00%Share
49NISA INVESTMENT ADVISORS, LLC387$00.00%Share
50XTX Topco Ltd576,707$00.00%Share

ZNTL Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202585$24.5B+2
Q3 202583$59.1B-16
Q2 202599$43.2B-32
Q1 2025131$70.4B-8
Q4 2024139$112.1B+29
Q3 2024110$1.5T-2
Q2 2024112$6.5T+5
Q1 2024107$478.7T—

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As of Q4 2025, 50 institutional investors hold ZNTL (Zentalis Pharmaceuticals, Inc.). The largest holder is 5AM Venture Management, LLC with $5.3B in shares. This quarter, 6 institutions opened new positions and 4 closed their positions.

Frequently Asked Questions

How many hedge funds own ZNTL?

As of Q4 2025, 50 institutional investors report holding ZNTL (Zentalis Pharmaceuticals, Inc.) in their 13F filings.

Who is the largest institutional holder of ZNTL?

The largest institutional holder of ZNTL is 5AM Venture Management, LLC with $5.3B in shares.

Is institutional ownership of ZNTL increasing or decreasing?

This quarter, 6 institutions opened new positions in ZNTL and 4 closed their positions.