Who Owns Milestone Pharmaceuticals Inc. (MIST)?Hedge Fund & Institutional Holders

$1.68-0.07 (-3.99%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$8.319506250003041e+123T

% of Float Held

4.907235813252118e+272%

QoQ Change in Holders

+15 / -7

Price History

$0.65$1.23$1.80$2.38$2.95Sep 24Jun 25Mar 26

MIST — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Simplify Asset Management Inc.New Position+1.5M+$3.0M
Stonepine Capital Management, LLCNew Position+663K+$1.3M
Valeo Financial Advisors, LLCNew Position+131K+$264K
ADAR1 Capital Management, LLCNew Position+100K+$202K
SG Americas Securities, LLCNew Position+97K+$197K
October Effect LtdNew Position+52K+$105K
Scientech Research LLCNew Position+30K+$60K
Invesco Ltd.New Position+22K+$44K
Stephenson & Company, Inc.New Position+20K+$40K
SJS Investment Consulting Inc.New Position+15K+$30K
Strategic Family Wealth Counselors, L.L.C.New Position+13K+$25K
Eaton Financial Holdings Company, LLCNew Position+13K+$25K
Bronte Capital Management Pty Ltd.New Position+10K+$21K
INTEGRAL INVESTMENT ADVISORS, INC.New Position+10K+$20K
Taylor Financial Group, Inc.New Position+10K+$20K

MIST — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
ADAGE CAPITAL PARTNERS GP, L.L.C.Decreased-4.2M-$13.9B
Propel Bio Management, LLCDecreased-1.0M-$10.2B
ORBIMED ADVISORS LLCClosed Position-3.2M-$6.4B
MORGAN STANLEYDecreased-2.2M-$5.9B
SPHERA FUNDS MANAGEMENT LTD.Closed Position-820K-$1.6B
Affinity Asset Advisors, LLCClosed Position-667K-$1.3B
CITADEL ADVISORS LLCDecreased-159K-$1.0B
GOLDMAN SACHS GROUP INCClosed Position-357K-$713.1M
Quadrature Capital LtdClosed Position-223K-$448.1M
XTX Topco LtdDecreased-15K-$374.6M
ROYAL BANK OF CANADADecreased-137K-$287.0M
STATE STREET CORPDecreased-345-$44.4M
BANK OF AMERICA CORP /DE/Decreased-15K-$32.1M
Wealthspire Advisors, LLCClosed Position-1K-$2.3M
HRT FINANCIAL LPClosed Position-139K-$277K

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Propel Bio Management, LLC4,118,321$8.3M7.10%Share
2RTW INVESTMENTS, LP2,506,102$5.1M0.05%Share
3ADAGE CAPITAL PARTNERS GP, L.L.C.2,810,037$5.0M0.01%Share
4Simplify Asset Management Inc.1,506,405$3.0M0.05%Share
5MARSHALL WACE, LLP1,617,063$3.0M0.00%Share
6TWO SIGMA INVESTMENTS, LP1,514,461$3.0M0.00%Share
7Pathstone Holdings, LLC1,017,040$2.0M0.01%Share
8Lion Point Capital, LP755,000$1.5M7.89%Share
9Boxer Capital Management, LLC666,666$1.3M0.29%Share
10Stonepine Capital Management, LLC662,666$1.3M0.98%Share
11MORGAN STANLEY731,539$1.0M0.00%Share
12JANE STREET GROUP, LLC581,846$1.0M0.00%Share
13TORONTO DOMINION BANK750,000$1.0M0.00%Share
14SUSQUEHANNA INTERNATIONAL GROUP, LLP643,300$1.0M0.00%Share
15SUSQUEHANNA INTERNATIONAL GROUP, LLP532,900$1.0M0.00%Put
16TWO SIGMA ADVISERS, LP619,592$1.0M0.00%Share
17UBS Group AG437,534$883K0.00%Share
18GROUP ONE TRADING LLC374,500$756K0.00%Put
19GUARDIAN WEALTH ADVISORS, LLC / NC263,200$531K0.03%Share
20GROUP ONE TRADING LLC195,099$394K0.00%Share
21GROUP ONE TRADING LLC165,400$334K0.00%Call
22Valeo Financial Advisors, LLC130,699$264K0.01%Share
23ADAR1 Capital Management, LLC100,100$202K0.01%Share
24SG Americas Securities, LLC97,375$197K0.00%Share
25Cascades Capital Asset Management, LLC77,510$156K0.07%Share
26UBS Group AG52,602$106K0.00%Share
27October Effect Ltd52,100$105K0.12%Share
28Scientech Research LLC30,124$60K0.04%Share
29Bay Rivers Group28,861$58K0.02%Share
30Safeguard Investment Advisory Group, LLC25,044$50K0.01%Share
31Invesco Ltd.21,893$44K0.00%Share
32Stephenson & Company, Inc.20,000$40K0.02%Share
33SJS Investment Consulting Inc.15,000$30K0.00%Share
34Beta Wealth Group, Inc.14,127$28K0.01%Share
35Strategic Family Wealth Counselors, L.L.C.12,675$25K0.01%Share
36Eaton Financial Holdings Company, LLC12,750$25K0.01%Share
37Bronte Capital Management Pty Ltd.10,414$21K0.00%Share
38Taylor Financial Group, Inc.10,000$20K0.01%Share
39INTEGRAL INVESTMENT ADVISORS, INC.10,000$20K0.00%Share
40Secure Asset Management, LLC10,000$20K0.00%Share
41US BANCORP \DE\3,200$6K0.00%Share
42UBS Group AG1,732$3K0.00%Share
43JOURNEY STRATEGIC WEALTH LLC10,000$00.00%Call
44LPL Financial LLC142,463$00.00%Share
45BNP PARIBAS FINANCIAL MARKETS221,951$00.00%Share
46Quantbot Technologies LP18,990$00.00%Share
47ACADIAN ASSET MANAGEMENT LLC176,200$00.00%Share
48GSA CAPITAL PARTNERS LLP236,138$00.00%Share
49Cambridge Investment Research Advisors, Inc.47,140$00.00%Share
50MORGAN STANLEY81$00.00%Share

MIST Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202576$41.9M+23
Q3 202553$61.2B+19
Q2 202534$13.2B-10
Q1 202544$9.5B-3
Q4 202447$107.2B+12
Q3 202435$25.3T+2
Q2 202433$15.4T+0
Q1 202433$21.8T—

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As of Q4 2025, 50 institutional investors hold MIST (Milestone Pharmaceuticals Inc.). The largest holder is Propel Bio Management, LLC with $8.3M in shares. This quarter, 15 institutions opened new positions and 7 closed their positions.

Frequently Asked Questions

How many hedge funds own MIST?

As of Q4 2025, 50 institutional investors report holding MIST (Milestone Pharmaceuticals Inc.) in their 13F filings.

Who is the largest institutional holder of MIST?

The largest institutional holder of MIST is Propel Bio Management, LLC with $8.3M in shares.

Is institutional ownership of MIST increasing or decreasing?

This quarter, 15 institutions opened new positions in MIST and 7 closed their positions.