DEERFIELD MANAGEMENT COMPANY, L.P. Q1 2023 Filing

Filed May 15, 2023

Portfolio Value

$4.5B

Holdings

106

Report Date

Q1 2023

Filing Type

13F-HR

All Holdings (106 positions)

#	Stock	Shares	Value	% Portfolio
1	SMFRUSDGENEDX HOLDINGS CORP	57,192,101	$20.0B	445.86%
2	AFIBACUTUS MED INC	2,651,667	$1.0B	22.29%
3	NUVLNUVALENT INC	19,991,024	$521.0M	11.61%
4	GKOS 2.75 06/15/27GLAUKOS CORP	271,752,000	$336.0M	7.49%
5	—CAREMAX INC	672,000	$323.8M	7.22%
6	—MEDAVAIL HOLDINGS INC	836,626	$239.8M	5.35%
7	BFLYWBUTTERFLY NETWORK INC	733,333	$195.1M	4.35%
8	NBIXNEUROCRINE BIOSCIENCES INC	1,744,714	$176.0M	3.92%
9	CPRXCATALYST PHARMACEUTICALS INC	10,355,099	$171.0M	3.81%
10	NTRA 2.25 05/01/27NATERA INC	101,042,000	$164.0M	3.66%
11	VTRSVIATRIS INC	16,935,997	$162.0M	3.61%
12	AHCOADAPTHEALTH CORP	10,594,914	$131.0M	2.92%
13	—TABULA RASA HEALTHCARE INC	144,516,000	$117.0M	2.61%
14	IONS 0 04/01/26IONIS PHARMACEUTICALS INC	127,800,000	$116.0M	2.59%
15	AMEDAMEDISYS INC	1,483,179	$109.0M	2.43%
16	BKD 2 10/15/26BROOKDALE SR LIVING INC	145,955,000	$104.0M	2.32%
17	—INTERCEPT PHARMACEUTICALS IN	98,354,000	$101.0M	2.25%
18	ACCD 0.5 04/01/26ACCOLADE INC	122,598,000	$96.0M	2.14%
19	APLS 3.5 09/15/26APELLIS PHARMACEUTICALS INC	51,793,000	$95.0M	2.12%
20	INSM 1.75 01/15/25INSMED INC	103,200,000	$94.0M	2.10%
21	TOIIWTHE ONCOLOGY INSTITUTE INC	1,250,000	$81.4M	1.81%
22	DCPHEURDECIPHERA PHARMACEUTICALS IN	5,218,638	$80.0M	1.78%
23	LRMRLARIMAR THERAPEUTICS INC	16,941,357	$76.0M	1.69%
24	PCRX 0.75 08/01/25PACIRA BIOSCIENCES INC	81,600,000	$75.0M	1.67%
25	SPRYARS PHARMACEUTICALS INC	11,077,927	$72.0M	1.61%
26	CNCCENTENE CORP DEL	1,075,000	$67.0M	1.49%
27	SILKSILK RD MED INC	1,725,640	$67.0M	1.49%
28	GH 0 11/15/27GUARDANT HEALTH INC	89,036,000	$59.0M	1.32%
29	AMLXAMYLYX PHARMACEUTICALS INC	1,984,333	$58.0M	1.29%
30	NSTG 2.625 03/01/25NANOSTRING TECHNOLOGIES INC	70,204,000	$58.0M	1.29%
31	—INTERCEPT PHARMACEUTICALS IN	57,791,000	$57.0M	1.27%
32	ACHOWENS & MINOR INC NEW	3,867,455	$56.0M	1.25%
33	QSIAWQUANTUM SI INC	333,333	$50.0M	1.11%
34	MIRMMIRUM PHARMACEUTICALS INC	2,032,335	$48.0M	1.07%
35	B7SBROOKDALE SR LIVING INC	16,406,047	$48.0M	1.07%
36	EHABENHABIT INC	3,398,746	$47.0M	1.05%
37	HLVXHILLEVAX INC	2,833,690	$46.0M	1.03%
38	TDOC 0.875 06/01/25LIVONGO HEALTH INC	50,000,000	$44.0M	0.98%
39	MRUSMERUS N V	2,380,438	$43.0M	0.96%
40	—CAREMAX INC	15,861,090	$42.0M	0.94%
41	SWTXSPRINGWORKS THERAPEUTICS INC	1,579,349	$40.0M	0.89%
42	ITCIEURINTRA-CELLULAR THERAPIES INC	734,000	$39.0M	0.87%
43	OPHTEURIVERIC BIO INC	1,504,578	$36.0M	0.80%
44	PTCT 1.5 09/15/26PTC THERAPEUTICS INC	32,000,000	$36.0M	0.80%
45	—SOMALOGIC INC	120,000	$36.0M	0.80%
46	NAMSNEWAMSTERDAM PHARMA COMPANY	2,535,723	$33.0M	0.74%
47	COGTCOGENT BIOSCIENCES INC	2,966,345	$32.0M	0.71%
48	EOLSEVOLUS INC	3,569,000	$30.0M	0.67%
49	KURAKURA ONCOLOGY INC	2,383,000	$29.0M	0.65%
50	HCAT 2.5 04/15/25HEALTH CATALYST INC	30,000,000	$27.0M	0.60%
51	EWTXEDGEWISE THERAPEUTICS INC	3,933,137	$26.0M	0.58%
52	LUNGPULMONX CORP	2,402,704	$26.0M	0.58%
53	DCGODOCGO INC	3,059,000	$26.0M	0.58%
54	BLUBELLUS HEALTH INC NEW	3,581,000	$25.0M	0.56%
55	TERNTERNS PHARMACEUTICALS INC	2,059,421	$24.0M	0.54%
56	KRYSKRYSTAL BIOTECH INC	311,949	$24.0M	0.54%
57	BCRXBIOCRYST PHARMACEUTICALS INC	2,765,000	$23.0M	0.51%
58	IDYAIDEAYA BIOSCIENCES INC	1,743,628	$23.0M	0.51%
59	—MEDTECH ACQUISITION CORP	333,333	$20.5M	0.46%
60	VTYXVENTYX BIOSCIENCES INC	617,000	$20.0M	0.45%
61	VIGLVIGIL NEUROSCIENCE INC	2,052,010	$20.0M	0.45%
62	NUVB/WSNUVATION BIO INC	166,666	$20.0M	0.45%
63	—SENIOR CONNECT ACQUISITN COR	500,000	$19.6M	0.44%
64	GHGUARDANT HEALTH INC	778,999	$18.0M	0.40%
65	VKTXVIKING THERAPEUTICS INC	1,125,000	$18.0M	0.40%
66	XERS 5 07/15/25XERIS BIOPHARMA HOLDINGS INC	18,000,000	$17.0M	0.38%
67	RVMDREVOLUTION MEDICINES INC	829,737	$17.0M	0.38%
68	SRZNWSURROZEN INC	166,666	$16.7M	0.37%
69	—DA32 LIFE SCNCE TEC ACQSTN C	1,600,000	$16.0M	0.36%
70	ATECALPHATEC HLDGS INC	1,046,791	$16.0M	0.36%
71	OSH 0 03/15/26OAK STR HEALTH INC	15,403,000	$15.0M	0.33%
72	TARSTARSUS PHARMACEUTICALS INC	1,156,032	$14.0M	0.31%
73	—INVITAE CORP	15,711,000	$14.0M	0.31%
74	—EUCRATES BIOMEDICAL ACQU COR	333,333	$13.5M	0.30%
75	DNLIDENALI THERAPEUTICS INC	594,989	$13.0M	0.29%
76	ANABANAPTYSBIO INC	613,000	$13.0M	0.29%
77	NVTA1EURINVITAE CORP	9,274,707	$12.0M	0.27%
78	ROIVROIVANT SCIENCES LTD	1,750,000	$12.0M	0.27%
79	IOVAIOVANCE BIOTHERAPEUTICS INC	1,831,607	$11.0M	0.25%
80	MLYSMINERALYS THERAPEUTICS INC	729,021	$11.0M	0.25%
81	IM8NINSMED INC	658,546	$11.0M	0.25%
82	PCVXVAXCYTE INC	295,000	$11.0M	0.25%
83	VERAVERA THERAPEUTICS INC	1,300,000	$10.0M	0.22%
84	—FUSION PHARMACEUTICALS INC	2,823,000	$10.0M	0.22%
85	PRMEPRIME MEDICINE INC	885,314	$10.0M	0.22%
86	NUVBNUVATION BIO INC	5,854,860	$9.0M	0.20%
87	GPCRSTRUCTURE THERAPEUTICS INC	375,000	$8.0M	0.18%
88	PACBPACIFIC BIOSCIENCES CALIF IN	650,000	$7.0M	0.16%
89	—SINGULAR GENOMICS SYSTEMS IN	6,450,871	$7.0M	0.16%
90	—BLUEBIRD BIO INC	2,175,000	$6.0M	0.13%
91	ALECALECTOR INC	1,055,192	$6.0M	0.13%
92	CSTLCASTLE BIOSCIENCES INC	272,135	$6.0M	0.13%
93	NEO 1.25 05/01/25NEOGENOMICS INC	6,500,000	$6.0M	0.13%
94	FHTXFOGHORN THERAPEUTICS INC	777,525	$4.0M	0.09%
95	CABACABALETTA BIO INC	464,252	$3.0M	0.07%
96	NYXHNYXOAH S A	455,262	$3.0M	0.07%
97	ABEOABEONA THERAPEUTICS INC	869,565	$2.0M	0.04%
98	ANNXANNEXON INC	583,913	$2.0M	0.04%
99	TOITHE ONCOLOGY INSTITUTE INC	3,360,052	$2.0M	0.04%
100	—RAIN ONCOLOGY INC	227,393	$1.0M	0.02%

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