DEERFIELD MANAGEMENT COMPANY, L.P.
CIK: 0001009258Latest portfolio: $7.8B · Q4 2025
Holdings
150
Total Value
$7.8B
New Positions
32
Closed Positions
34
Top Holdings
View All 150 Holdings →| # | Stock | Shares | Value | % Portfolio | Change | Type |
|---|---|---|---|---|---|---|
| 1 | NUVLNUVALENT INC | 17,248,450 | $1.7B | 22.16% | -742,574 | |
| 2 | BKD 3.5 10/15/29BROOKDALE SR LIVING INC | 306,885,000 | $427.5M | 5.46% | NEW | |
| 3 | COGTCOGENT BIOSCIENCES INC | 9,043,903 | $321.2M | 4.10% | -9,215 | |
| 4 | PRAXPRAXIS PRECISION MEDICINES I | 903,351 | $266.3M | 3.40% | +63K | |
| 5 | CNCCENTENE CORP DEL | 6,447,998 | $265.3M | 3.39% | -2,598,002 | |
| 6 | VTRSVIATRIS INC | 20,206,170 | $251.6M | 3.21% | -3,892,913 | |
| 7 | RVMDREVOLUTION MEDICINES INC | 2,894,613 | $230.6M | 2.94% | -755,729 | |
| 8 | UTHUNITED THERAPEUTICS CORP DEL | 425,993 | $207.6M | 2.65% | — | |
| 9 | VERAVERA THERAPEUTICS INC | 4,059,695 | $205.6M | 2.63% | +419K | |
| 10 | MIRM 4 05/01/29MIRUM PHARMACEUTICALS INC | 70,000,000 | $180.7M | 2.31% | — | |
| 11 | CELCCELCUITY INC | 1,714,000 | $171.0M | 2.18% | +980K | |
| 12 | NBIXNEUROCRINE BIOSCIENCES INC | 1,184,345 | $168.0M | 2.15% | — | |
| 13 | ISIIONIS PHARMACEUTICALS INC | 1,979,669 | $156.6M | 2.00% | — | |
| 14 | NAMSNEWAMSTERDAM PHARMA COMPANY | 4,164,789 | $146.1M | 1.87% | -101,904 | |
| 15 | INSPINSPIRE MED SYS INC | 1,505,872 | $138.9M | 1.77% | +458K | |
| 16 | LEGNLEGEND BIOTECH CORP | 5,932,000 | $129.0M | 1.65% | +3.0M | |
| 17 | B7SBROOKDALE SR LIVING INC | 11,637,032 | $125.6M | 1.60% | -4,610 | |
| 18 | —INDIVIOR PLC | 3,393,063 | $121.7M | 1.55% | -3,593,748 | |
| 19 | ARWRARROWHEAD PHARMACEUTICALS IN | 1,832,946 | $121.7M | 1.55% | +840K | |
| 20 | LRMRLARIMAR THERAPEUTICS INC | 30,606,974 | $116.6M | 1.49% | — | |
| 21 | CPRXCATALYST PHARMACEUTICALS INC | 4,911,161 | $114.6M | 1.46% | -63,606 | |
| 22 | AHCOADAPTHEALTH CORP | 11,477,730 | $114.3M | 1.46% | — | |
| 23 | BCRXBIOCRYST PHARMACEUTICALS INC | 14,341,000 | $111.9M | 1.43% | +2.2M | |
| 24 | IONS 1.75 06/15/28IONIS PHARMACEUTICALS INC | 60,000,000 | $95.3M | 1.22% | — | |
| 25 | ALHC 4.25 11/15/29ALIGNMENT HEALTHCARE INC | 61,000,000 | $92.6M | 1.18% | NEW |
Quarterly Changes
New Positions
Increased Positions
Sector Breakdown
HealthcareNaN% ($InfinityT)
Unknown0.0% ($4.2749320756518074e+98T)
Industrials0.0% ($33.9B)
Financial Services0.0% ($24.8B)
Consumer Cyclical0.0% ($2.6B)
Consumer Defensive0.0% ($1.1B)
Technology0.0% ($150K)
Filing History
| Quarter | Filing Date | Portfolio Value | Holdings |
|---|---|---|---|
| Q4 2025 | Feb 17, 2026 | $7.8B | 150 |
| Q3 2025 | Nov 14, 2025 | $6.6T | 152 |
| Q2 2025 | Aug 14, 2025 | $5.5T | 124 |
| Q1 2025 | May 15, 2025 | $5.1T | 123 |
| Q4 2024 | Feb 14, 2025 | $5.3T | 106 |
| Q3 2024 | Nov 14, 2024 | $6692.8T | 443 |
| Q2 2024 | Aug 14, 2024 | $6010.5T | 433 |
| Q1 2024 | May 15, 2024 | $5748.1T | 367 |
| Q4 2023 | Feb 14, 2024 | $5415.6T | 222 |
| Q3 2023 | Nov 14, 2023 | $4538.8T | 88 |
| Q2 2023 | Aug 14, 2023 | $4684.2T | 101 |
| Q1 2023 | May 15, 2023 | $4485.7T | 106 |
| Q4 2022 | Feb 14, 2023 | $4831.0T | 104 |
| Q3 2022 | Nov 14, 2022 | $5.0T | 132 |
| Q2 2022 | Aug 15, 2022 | $4.8T | 127 |
| Q1 2022 | May 16, 2022 | $4.5T | 122 |
| Q4 2021 | Feb 14, 2022 | $4.8T | 127 |
| Q3 2021 | Nov 15, 2021 | $5.1T | 133 |
| Q2 2021 | Aug 16, 2021 | $5.6T | 143 |
| Q1 2021 | May 17, 2021 | $4.8T | 133 |
| Q4 2020 | Feb 16, 2021 | $5.1T | 129 |
| Q3 2020 | Nov 16, 2020 | $4.1T | 105 |
| Q2 2020 | Aug 14, 2020 | $3.4T | 93 |
| Q1 2020 | May 15, 2020 | $3.2T | 90 |
| Q4 2019 | Feb 14, 2020 | $3.1T | 76 |
| Q3 2019 | Nov 14, 2019 | $2.5T | 95 |
| Q2 2019 | Aug 14, 2019 | $2.8T | 97 |
| Q1 2019 | May 15, 2019 | $2.6T | 93 |
| Q4 2018 | Feb 14, 2019 | $2.5T | 99 |
| Q3 2018 | Nov 14, 2018 | $2.8T | 103 |
| Q2 2018 | Aug 14, 2018 | $2.8T | 114 |
| Q1 2018 | May 15, 2018 | $2.9T | 118 |
| Q4 2017 | Feb 14, 2018 | $2.5T | 98 |
| Q3 2017 | Nov 13, 2017 | $2.2T | 91 |
| Q2 2017 | Aug 14, 2017 | $1.9T | 85 |
| Q1 2017 | May 15, 2017 | $2.6T | 106 |
| Q4 2016 | Feb 14, 2017 | $2.4T | 102 |
| Q3 2016 | Nov 14, 2016 | $2.2T | 90 |
| Q2 2016 | Aug 15, 2016 | $2.5T | 106 |
| Q1 2016 | May 16, 2016 | $2.3T | 105 |
Fund Information
DEERFIELD MANAGEMENT COMPANY, L.P. is an institutional investment manager that files 13F reports with the SEC. As of the Q4 2025 filing, the fund reported a portfolio valued at $7.8B across 150 holdings. The largest position is NUVALENT INC (NUVL), representing 22.2% of the portfolio. Compared to the previous quarter, the fund opened 33 new positions and closed 35 positions. 13F filings are required quarterly disclosures that provide transparency into the holdings of institutional investment managers with at least $100 million in qualifying assets.