Siren, L.L.C. Q4 2024 Filing
Filed February 14, 2025
Portfolio Value
$2.3B
Holdings
117
Report Date
Q4 2024
Filing Type
13F-HR
All Holdings (117 positions)
| Stock | Value |
|---|---|
SRRKScholar Rock Holding Corp | $399.8M |
ONCBeigene Ltd | $120.7M |
KYMRKymera Therapeutics Inc | $119.5M |
APLSApellis Pharmaceuticals Inc | $89.9M |
CRNXCrinetics Pharmaceuticals Inc | $82.3M |
ARGXargenx SE | $70.8M |
BCAXBicara Therapeutics Inc | $57.0M |
ARWRArrowhead Pharmaceuticals Inc | $54.6M |
NAMSNewAmsterdam Pharma Company NV | $53.9M |
SEPNSepterna Inc | $50.4M |
CNTACentessa Pharmaceuticals PLC | $50.3M |
SWTXSpringWorks Therapeutics Inc | $49.8M |
NMRANeumora Therapeutics Inc | $46.6M |
WVEWAVE Life Sciences Ltd | $46.4M |
ASNDAscendis Pharma A/S | $40.9M |
MDGLMadrigal Pharmaceuticals Inc | $38.9M |
TBLATaboola.com Ltd | $36.4M |
APGEApogee Therapeutics Inc | $33.9M |
MRUSMerus NV | $33.0M |
RNAAvidity Biosciences Inc | $32.8M |
VERAVera Therapeutics Inc | $32.1M |
DYNDyne Therapeutics Inc | $31.7M |
XENEXenon Pharmaceuticals Inc | $29.2M |
LXRXLexicon Pharmaceuticals Inc | $28.8M |
BCYCBicycle Therapeutics PLC | $25.8M |
RVMDRevolution Medicines Inc | $25.0M |
PCVXVaxcyte Inc | $24.6M |
RCUSArcus Biosciences Inc | $24.0M |
ERASErasca Inc | $22.2M |
STOKStoke Therapeutics Inc | $22.1M |
1K0IGM Biosciences Inc | $20.3M |
EWTXEdgewise Therapeutics Inc | $19.6M |
SLNSilence Therapeutics PLC | $19.5M |
CYTKCytokinetics Inc | $18.9M |
DNLIDenali Therapeutics Inc | $17.0M |
KRROKorro Bio Inc | $15.9M |
SLNOSoleno Therapeutics Inc | $15.8M |
PRTAProthena Corporation PLC | $15.2M |
SLDBSolid Biosciences Inc | $15.0M |
CGEMCullinan Therapeutics Inc | $14.8M |
UPBUpstream Bio Inc | $13.2M |
TRVITrevi Therapeutics Inc | $12.0M |
KURAKura Oncology Inc | $11.7M |
TSHATaysha Gene Therapies Inc | $11.4M |
RELYRemitly Global Inc | $11.1M |
RNACCartesian Therapeutics Inc | $10.2M |
MSFTMicrosoft Corp | $9.7M |
JANXJanux Therapeutics Inc | $9.4M |
SEERSeer Inc | $9.2M |
ISIIonis Pharmaceuticals Inc | $8.7M |
SYRESpyre Therapeutics Inc | $8.7M |
CRWDCrowdStrike Holdings Inc | $8.2M |
IOVAIovance Biotherapeutics Inc | $8.2M |
ORICOric Pharmaceuticals Inc | $8.1M |
TNGXTango Therapeutics Inc | $8.0M |
AMZNAmazon.com Inc | $8.0M |
RCKTRocket Pharmaceuticals Inc | $7.5M |
IONQIONQ Inc | $7.1M |
IHSIHS Holding Limited | $6.9M |
RAPPRapport Therapeutics Inc | $6.8M |
NVDANVIDIA Corp | $6.6M |
NOWServiceNow Inc | $5.9M |
SLRNACELYRIN Inc | $5.4M |
PDDPDD Holdings Inc | $5.1M |
GOSSGossamer Bio Inc | $4.9M |
DTDynatrace Inc | $4.5M |
BABoeing Co | $4.4M |
N1UANew Oriental Education & Technology Group Inc | $4.4M |
DDOGDatadog Inc | $4.3M |
PRQRProQR Therapeutics NV | $4.2M |
LXEOLexeo Therapeutics Inc | $4.0M |
ADBEAdobe Inc | $3.9M |
PHATPhathom Pharmaceuticals Inc | $3.7M |
TILInstil Bio Inc | $3.7M |
FROGJfrog Ltd | $3.5M |
FHTXFoghorn Therapeutics Inc. | $3.4M |
VIGLVigil Neuroscience Inc | $3.4M |
NBISNebius Group NV | $3.3M |
SGMTSagimet Biosciences Inc | $3.3M |
GBIOGBXGeneration Bio Co | $3.2M |
TSMTaiwan Semiconductor Manufacturing Co Ltd | $3.0M |
FCXFreeport-McMoRan Inc | $2.9M |
—Allovir Inc | $2.8M |
OVIDOvid Therapeutics Inc | $2.7M |
SESea Ltd | $2.7M |
ESTCElastic NV | $2.5M |
QCOMQualcomm Inc | $2.3M |
BIOABIOAGE Labs Inc | $2.2M |
BDTXBlack Diamond Therapeutics Inc | $2.2M |
RGNXRegenxbio Inc | $2.2M |
TRMLTourmaline Bio Inc | $1.9M |
PCORProcore Technologies Inc | $1.5M |
APLTApplied Therapeutics Inc | $1.4M |
GOOGLAlphabet Inc | $1.3M |
PYPLPayPal Holdings Inc | $1.3M |
HOOKHOOKIPA Pharma Inc | $1.1M |
HCAHCA Healthcare Inc | $1.1M |
BEKEKe Holdings Inc | $1.1M |
WKWorkiva Inc | $1.1M |
PANWPalo Alto Networks Inc | $1.1M |
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