Who Owns UPB?

Upstream Bio, Inc. — Institutional Ownership & 13F Holdings

$9.18

-0.01 (-0.16%)

Market Cap

$506.1M

Shares Outstanding

54,419,986

Institutional Holders

78

Total Inst. Value

$259.8M

% of Float Held

227.2%

QoQ Holder Change

Institutional data as of Q1 2025

Top 10 Institutional Holders(Q1 2025)

#FundValueShares
1FMR LLC$44.4M7,255,859
2ORBIMED ADVISORS LLC$34.8M5,693,589
3Decheng Capital LLC$20.1M3,285,293
4TCG Crossover Management, LLC$17.1M2,801,763
5Enavate Sciences GP, LLC$15.1M2,459,703
6Deep Track Capital, LP$14.1M2,299,567
7Bain Capital Life Sciences Investors, LLC$14.0M2,295,322
8VR Adviser, LLC$14.0M2,295,319
9Samsara BioCapital, LLC$12.7M2,067,146
10Omega Fund Management, LLC$12.5M2,036,293

Biggest Buyers & Sellers This Quarter

Top Buyers

FundShares AddedValue
FMR LLC+80K$44.4M
Deep Track Capital, LP+1.3M$14.1M
BlackRock, Inc.+68K$7.3M
Woodline Partners LP+31K$3.4M
GEODE CAPITAL MANAGEMENT, LLC+47K$2.5M

Top Sellers

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Frequently Asked Questions

How many institutional investors hold UPB?

As of Q1 2025, 78 institutional investors report holding UPB (Upstream Bio, Inc.) in their 13F filings.

What percentage of Upstream Bio, Inc. is owned by institutions?

Institutional investors hold approximately 227.2% of Upstream Bio, Inc.'s float as reported in SEC 13F filings.

Which hedge fund owns the most UPB?

The largest institutional holder of UPB is FMR LLC with $44.4M in shares.

Are institutions buying or selling UPB?

This quarter, 26 institutions opened new positions in UPB and 15 closed their positions.

What is 13F institutional ownership?

SEC Form 13F is a quarterly report filed by institutional investment managers with over $100M in qualifying assets. It discloses their US equity holdings, providing transparency into what the largest investors are buying and selling.

How often is institutional ownership data updated?

13F filings are due 45 days after each calendar quarter end (May 15, Aug 14, Nov 14, Feb 14). Data is updated on HedgeTrace as new filings are processed.