DEERFIELD MANAGEMENT COMPANY, L.P. Q3 2021 Filing
Filed November 15, 2021
Portfolio Value
$5.1B
Holdings
133
Report Date
Q3 2021
Filing Type
13F-HR
All Holdings (133 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | NUVLNUVALENT INC | 19,341,024 | $436.1B | 8511.84% | |
| 2 | VTRSVIATRIS INC | 18,824,000 | $255.1B | 4977.93% | |
| 3 | —INVITAE CORP | 163,385,000 | $199.6B | 3896.33% | |
| 4 | AHCOADAPTHEALTH CORP | 8,103,792 | $188.7B | 3683.45% | |
| 5 | —CAREMAX INC | 16,778,750 | $162.1B | 3163.26% | |
| 6 | —AERIE PHARMACEUTICALS INC | 157,390,000 | $143.8B | 2807.26% | |
| 7 | NTRA 2.25 05/01/27NATERA INC | 45,000,000 | $135.2B | 2639.31% | |
| 8 | GKOS 2.75 06/15/27GLAUKOS CORP | 108,000,000 | $129.6B | 2530.13% | |
| 9 | BBIO 2.5 03/15/27BRIDGEBIO PHARMA INC | 80,000,000 | $110.5B | 2156.53% | |
| 10 | NBIXNEUROCRINE BIOSCIENCES INC | 1,142,415 | $109.6B | 2138.38% | |
| 11 | NVST 2.375 06/01/25ENVISTA HOLDINGS CORPORATION | 52,500,000 | $109.2B | 2131.28% | |
| 12 | ORGOORGANOGENESIS HLDGS INC | 7,462,543 | $106.3B | 2073.94% | |
| 13 | SMFRUSDSEMA4 HOLDINGS CORP | 13,848,488 | $105.1B | 2051.36% | |
| 14 | —SINGULAR GENOMICS SYSTEMS IN | 9,112,019 | $102.0B | 1989.94% | |
| 15 | GMED 1 06/01/23NUVASIVE INC | 96,966,000 | $98.8B | 1928.09% | |
| 16 | PCRX 0.75 08/01/25PACIRA BIOSCIENCES INC | 81,600,000 | $87.7B | 1712.03% | |
| 17 | PODD 0.375 09/01/26INSULET CORP | 57,581,000 | $80.4B | 1569.25% | |
| 18 | OPHTEURIVERIC BIO INC | 4,863,725 | $79.0B | 1541.53% | |
| 19 | LUNGPULMONX CORP | 2,029,887 | $73.0B | 1425.37% | |
| 20 | LRMRLARIMAR THERAPEUTICS INC | 5,830,249 | $67.2B | 1311.94% | |
| 21 | MIRMMIRUM PHARMACEUTICALS INC | 3,282,912 | $65.4B | 1276.29% | |
| 22 | EWTXEDGEWISE THERAPEUTICS INC | 3,933,137 | $65.3B | 1274.22% | |
| 23 | MOHMOLINA HEALTHCARE INC | 231,776 | $62.9B | 1227.24% | |
| 24 | CNCCENTENE CORP DEL | 1,003,800 | $62.5B | 1220.69% | |
| 25 | INSM 0.75 06/01/28INSMED INC | 50,000,000 | $55.1B | 1075.74% | |
| 26 | CYTKCYTOKINETICS INC | 1,536,758 | $54.9B | 1071.91% | |
| 27 | SILKSILK RD MED INC | 990,251 | $54.5B | 1063.52% | |
| 28 | PCRXPACIRA BIOSCIENCES INC | 967,236 | $54.2B | 1057.10% | |
| 29 | GMED 0.375 03/15/25NUVASIVE INC | 55,800,000 | $54.1B | 1056.03% | |
| 30 | —APRIA INC | 1,417,700 | $52.7B | 1027.88% | |
| 31 | —INTERCEPT PHARMACEUTICALS IN | 57,791,000 | $52.1B | 1017.21% | |
| 32 | INSM 1.75 01/15/25INSMED INC | 50,000,000 | $51.7B | 1009.23% | |
| 33 | —DFP HEALTHCARE ACQUISITNS CO | 5,000,000 | $49.7B | 969.96% | |
| 34 | ATECALPHATEC HLDGS INC | 3,594,829 | $43.8B | 855.22% | |
| 35 | KURAKURA ONCOLOGY INC | 2,315,417 | $43.4B | 846.38% | |
| 36 | RVMDREVOLUTION MEDICINES INC | 1,565,712 | $43.1B | 840.63% | |
| 37 | NVAX 3.75 02/01/23NATERA INC | 25,000,000 | $43.1B | 840.29% | |
| 38 | DAWNDAY ONE BIOPHARMACEUTICALS I | 1,710,730 | $40.6B | 792.28% | |
| 39 | MR4MERIDIAN BIOSCIENCE INC | 2,063,083 | $39.7B | 774.68% | |
| 40 | KALVKALVISTA PHARMACEUTICALS INC | 2,163,554 | $37.8B | 736.82% | |
| 41 | —TABULA RASA HEALTHCARE INC | 45,000,000 | $37.5B | 730.89% | |
| 42 | NUVBNUVATION BIO INC | 3,577,233 | $35.6B | 693.96% | |
| 43 | APLS 3.5 09/15/26APELLIS PHARMACEUTICALS INC | 28,825,000 | $35.5B | 692.79% | |
| 44 | NVRO 2.75 04/01/25NEVRO CORP NOTE | 26,000,000 | $34.9B | 680.65% | |
| 45 | AERIEURAERIE PHARMACEUTICALS INC | 2,977,020 | $33.9B | 662.34% | |
| 46 | —BIODELIVERY SCIENCES INTL IN | 9,170,699 | $33.1B | 646.11% | |
| 47 | B7SBROOKDALE SR LIVING INC | 5,252,800 | $33.1B | 645.85% | |
| 48 | SWTXSPRINGWORKS THERAPEUTICS INC | 510,673 | $32.4B | 632.27% | |
| 49 | HOWLWEREWOLF THERAPEUTICS INC | 1,752,787 | $30.1B | 587.01% | |
| 50 | GKOSGLAUKOS CORP | 619,000 | $29.8B | 581.92% | |
| 51 | —ONCORUS INC | 3,148,977 | $29.4B | 573.99% | |
| 52 | PHVSPHARVARIS N V | 1,608,471 | $28.5B | 556.57% | |
| 53 | DCPHEURDECIPHERA PHARMACEUTICALS IN | 815,000 | $27.7B | 540.48% | |
| 54 | INZYINOZYME PHARMA INC | 2,344,786 | $27.2B | 530.38% | |
| 55 | HCAT 2.5 04/15/25HEALTH CATALYST INC | 15,000,000 | $26.3B | 513.12% | |
| 56 | RYTMRHYTHM PHARMACEUTICALS INC | 1,989,625 | $26.0B | 507.13% | |
| 57 | XLRNACCELERON PHARMA INC | 145,000 | $25.0B | 487.03% | |
| 58 | PTGXPROTAGONIST THERAPEUTICS INC | 1,394,000 | $24.7B | 482.09% | |
| 59 | TERNTERNS PHARMACEUTICALS INC | 2,345,959 | $24.4B | 477.08% | |
| 60 | ALECALECTOR INC | 1,055,192 | $24.1B | 469.93% | |
| 61 | PMVPPMV PHARMACEUTICALS INC | 804,000 | $24.0B | 467.59% | |
| 62 | —KINNATE BIOPHARMA INC | 1,028,508 | $23.7B | 462.07% | |
| 63 | CGEMCULLINAN ONCOLOGY INC | 1,044,000 | $23.6B | 459.86% | |
| 64 | AFIBACUTUS MED INC | 2,648,386 | $23.4B | 456.92% | |
| 65 | —VINCERX PHARMA INC | 1,379,310 | $22.3B | 435.27% | |
| 66 | FATEFATE THERAPEUTICS INC | 362,000 | $21.5B | 418.74% | |
| 67 | —ITAMAR MED LTD | 694,667 | $21.0B | 409.71% | |
| 68 | TILINSTIL BIO INC | 1,115,739 | $19.9B | 389.23% | |
| 69 | OMGBPOUTSET MED INC | 400,622 | $19.8B | 386.56% | |
| 70 | 2L9BLUEPRINT MEDICINES CORP | 185,354 | $19.1B | 371.90% | |
| 71 | PRNPROFOUND MED CORP | 1,297,797 | $19.0B | 370.81% | |
| 72 | XERS 5 07/15/25XERIS PHARMACEUTICALS INC | 18,000,000 | $18.9B | 368.16% | |
| 73 | —MONTES ARCHIMEDES ACQUISITIO | 2,000,000 | $18.7B | 364.95% | |
| 74 | —GRAYBUG VISION INC | 5,281,713 | $17.5B | 342.22% | |
| 75 | ERASERASCA INC | 786,660 | $16.7B | 325.79% | |
| 76 | LPTXEURLEAP THERAPEUTICS INC | 4,000,000 | $16.0B | 313.04% | |
| 77 | ORTXUSDORCHARD THERAPEUTICS PLC | 6,949,416 | $16.0B | 311.95% | |
| 78 | WVEWAVE LIFE SCIENCES LTD | 3,214,340 | $15.8B | 307.38% | |
| 79 | —DA32 LIFE SCNCE TEC ACQSTN C | 1,600,000 | $15.7B | 306.95% | |
| 80 | —PTC THERAPEUTICS INC NOTE | 14,527,000 | $15.1B | 293.94% | |
| 81 | AVTEAEROVATE THERAPEUTICS INC | 714,285 | $15.0B | 292.47% | |
| 82 | GRPHGRAPHITE BIO INC | 906,308 | $14.9B | 289.90% | |
| 83 | BCABBIOATLA INC | 464,300 | $13.7B | 266.77% | |
| 84 | COGTCOGENT BIOSCIENCES INC | 1,601,000 | $13.5B | 262.77% | |
| 85 | SPRBSPRUCE BIOSCIENCES INC | 2,200,000 | $13.2B | 258.04% | |
| 86 | QSIQUANTUM SI INC | 1,400,000 | $11.7B | 227.87% | |
| 87 | RXSTRXSIGHT INC | 900,000 | $11.4B | 222.54% | |
| 88 | TYRATYRA BIOSCIENCES INC | 625,000 | $11.0B | 214.56% | |
| 89 | ANNXANNEXON INC | 583,913 | $10.9B | 212.08% | |
| 90 | DHDEFINITIVE HEALTHCARE CORP | 250,000 | $10.7B | 208.98% | |
| 91 | —EUCRATES BIOMEDICAL ACQU COR | 1,000,000 | $9.9B | 194.19% | |
| 92 | TLSIMEDTECH ACQUISITION CORP | 999,999 | $9.9B | 193.80% | |
| 93 | —SARISSA CAPITAL ACQUISITN CO | 1,000,000 | $9.9B | 192.74% | |
| 94 | —SENIOR CONNECT ACQUISITN COR | 1,000,000 | $9.8B | 190.67% | |
| 95 | —REVOLUTION HEALTHCAR AQ CORP | 1,000,000 | $9.7B | 189.50% | |
| 96 | HLTHQCUE HEALTH INC | 798,867 | $9.4B | 184.14% | |
| 97 | AUPHAURINIA PHARMACEUTICALS INC | 425,300 | $9.4B | 183.69% | Put |
| 98 | AMWLAMERICAN WELL CORP | 991,115 | $9.0B | 176.21% | |
| 99 | GHRSGH RESEARCH PLC | 405,416 | $8.9B | 174.53% | |
| 100 | NYXHNYXOAH S A | 300,800 | $8.8B | 171.68% |
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