RTW INVESTMENTS, LP Q3 2021 Filing
Filed November 15, 2021
Portfolio Value
$6.6B
Holdings
120
Report Date
Q3 2021
Filing Type
13F-HR
All Holdings (120 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | RCKTROCKET PHARMACEUTICALS INC | 15,802,802 | $469.6B | 7081.96% | |
| 2 | SPYSPDR S&P 500 ETF TR | 873,255 | $374.7B | 5651.52% | |
| 3 | ALNYALNYLAM PHARMACEUTICALS INC | 1,683,362 | $317.8B | 4793.22% | |
| 4 | MRTXEURMIRATI THERAPEUTICS INC | 1,492,532 | $264.0B | 3982.00% | |
| 5 | TMOTHERMO FISHER SCIENTIFIC INC | 416,000 | $237.7B | 3584.30% | |
| 6 | 3M4MASIMO CORP | 832,540 | $225.4B | 3398.87% | |
| 7 | VCELVERICEL CORP | 4,517,570 | $220.5B | 3324.67% | |
| 8 | TCE2CELLDEX THERAPEUTICS INC NEW | 3,908,947 | $211.0B | 3182.71% | |
| 9 | NTRANATERA INC | 1,862,234 | $207.5B | 3129.68% | |
| 10 | PTCTPTC THERAPEUTICS INC | 5,293,966 | $197.0B | 2970.74% | |
| 11 | ILMNILLUMINA INC | 482,791 | $195.8B | 2953.20% | |
| 12 | ESTAESTABLISHMENT LABS HLDGS INC | 2,319,138 | $166.0B | 2503.47% | |
| 13 | —DICERNA PHARMACEUTICALS INC | 7,582,396 | $152.9B | 2305.27% | |
| 14 | TNDMTANDEM DIABETES CARE INC | 1,160,734 | $138.6B | 2089.72% | |
| 15 | GMEDGLOBUS MED INC | 1,670,811 | $128.0B | 1930.62% | |
| 16 | AXNX*AXONICS INC | 1,943,864 | $126.5B | 1908.11% | |
| 17 | RNAAVIDITY BIOSCIENCES INC | 4,795,000 | $118.1B | 1781.06% | |
| 18 | GHGUARDANT HEALTH INC | 925,342 | $115.7B | 1744.50% | |
| 19 | CCCCC4 THERAPEUTICS INC | 2,494,965 | $111.5B | 1681.13% | |
| 20 | OPHTEURIVERIC BIO INC | 6,722,624 | $109.2B | 1646.45% | |
| 21 | FULCFULCRUM THERAPEUTICS INC | 3,855,291 | $108.8B | 1640.16% | |
| 22 | TXG10X GENOMICS INC | 734,481 | $106.9B | 1612.53% | |
| 23 | PENPENUMBRA INC | 385,194 | $102.7B | 1548.11% | |
| 24 | DMTKQDERMTECH INC | 3,118,665 | $100.1B | 1510.19% | |
| 25 | STOKSTOKE THERAPEUTICS INC | 3,644,248 | $92.7B | 1398.14% | |
| 26 | IDYAIDEAYA BIOSCIENCES INC | 3,266,255 | $83.3B | 1255.58% | |
| 27 | MGNXMACROGENICS INC | 3,975,554 | $83.2B | 1255.45% | |
| 28 | —PROMETHEUS BIOSCIENCES INC | 3,264,031 | $77.4B | 1167.10% | |
| 29 | RGNXREGENXBIO INC | 1,845,366 | $77.4B | 1166.62% | |
| 30 | CYTKCYTOKINETICS INC | 2,000,000 | $71.5B | 1077.98% | |
| 31 | 5E7ITEOS THERAPEUTICS INC | 2,353,015 | $63.5B | 958.10% | |
| 32 | —LANDOS BIOPHARMA INC | 4,275,722 | $62.4B | 941.43% | |
| 33 | CUTREURCUTERA INC | 1,257,862 | $58.6B | 883.98% | |
| 34 | AVDLAVADEL PHARMACEUTICALS PLC | 5,741,939 | $56.3B | 848.61% | |
| 35 | PRQRPROQR THRAPEUTICS N V | 6,443,113 | $53.9B | 813.29% | |
| 36 | AXSMAXSOME THERAPEUTICS INC | 1,616,497 | $53.3B | 803.51% | |
| 37 | TNYATENAYA THERAPEUTICS INC | 2,458,750 | $48.6B | 732.64% | |
| 38 | AGENEURAGENUS INC | 9,074,438 | $47.6B | 718.46% | |
| 39 | APYXAPYX MEDICAL CORPORATION | 3,398,279 | $47.1B | 709.79% | |
| 40 | IMCRIMMUNOCORE HLDGS PLC | 1,245,532 | $46.2B | 696.31% | |
| 41 | GHRSGH RESEARCH PLC | 2,168,957 | $45.7B | 689.48% | |
| 42 | OMGBPOUTSET MED INC | 894,652 | $44.2B | 667.05% | |
| 43 | TARSTARSUS PHARMACEUTICALS INC | 2,013,601 | $43.4B | 654.40% | |
| 44 | ARGXARGENX SE | 140,311 | $42.4B | 639.03% | |
| 45 | LUNGPULMONX CORP | 1,164,600 | $41.9B | 631.92% | |
| 46 | RLMDRELMADA THERAPEUTICS INC | 1,538,026 | $40.3B | 607.94% | |
| 47 | CSTLCASTLE BIOSCIENCES INC | 599,009 | $39.8B | 600.73% | |
| 48 | NSTGEURNANOSTRING TECHNOLOGIES INC | 804,029 | $38.6B | 582.13% | |
| 49 | —OLINK HLDG AB | 1,318,188 | $32.0B | 482.07% | |
| 50 | PTGXPROTAGONIST THERAPEUTICS INC | 1,753,695 | $31.1B | 468.64% | |
| 51 | BLUBELLUS HEALTH INC NEW | 4,968,017 | $30.4B | 458.92% | |
| 52 | SGHTSIGHT SCIENCES INC | 1,283,871 | $29.1B | 439.52% | |
| 53 | JNJJOHNSON & JOHNSON | 170,542 | $27.5B | 415.37% | |
| 54 | GLUEMONTE ROSA THERAPEUTICS INC | 1,214,572 | $26.0B | 392.18% | |
| 55 | CLSDUSDCLEARSIDE BIOMEDICAL INC | 4,206,765 | $25.2B | 380.65% | |
| 56 | MISTMILESTONE PHARMACEUTICALS IN | 4,315,102 | $24.6B | 371.58% | |
| 57 | PMVPPMV PHARMACEUTICALS INC | 809,863 | $24.1B | 363.96% | |
| 58 | —GENETRON HLDGS LTD | 1,671,894 | $23.2B | 349.21% | |
| 59 | OYSTOYSTER PT PHARMA INC | 1,861,209 | $22.1B | 332.61% | |
| 60 | WHWKAADI BIOSCIENCES INC | 764,701 | $21.3B | 321.76% | |
| 61 | EPIEURESSA PHARMA INC | 2,637,192 | $21.1B | 318.17% | |
| 62 | I9DNARBUTUS BIOPHARMA CORP | 4,733,323 | $20.3B | 306.23% | |
| 63 | INMDINMODE LTD | 124,999 | $19.9B | 300.58% | |
| 64 | CERE1EURCEREVEL THERAPEUTICS HLDNG I | 666,666 | $19.7B | 296.59% | |
| 65 | —RENOVACOR INC | 2,187,540 | $19.3B | 290.37% | |
| 66 | TELATELA BIO INC | 1,391,619 | $19.0B | 286.69% | |
| 67 | —ATHIRA PHARMA INC | 1,906,557 | $17.9B | 269.71% | |
| 68 | ADVMCHFADVERUM BIOTECHNOLOGIES INC | 7,483,757 | $16.2B | 244.91% | |
| 69 | NEONEOGENOMICS INC | 311,111 | $14.9B | 224.30% | |
| 70 | URGNUROGEN PHARMA LTD | 857,464 | $14.4B | 217.51% | |
| 71 | EP3ORASURE TECHNOLOGIES INC | 1,174,722 | $13.3B | 200.36% | |
| 72 | BWAYBRAINSWAY LTD | 1,602,381 | $12.9B | 194.77% | |
| 73 | IMUXIMMUNIC INC | 1,370,814 | $12.1B | 182.96% | |
| 74 | —VINCERX PHARMA INC | 749,999 | $12.1B | 182.88% | |
| 75 | XGNEXAGEN INC | 821,414 | $11.2B | 168.47% | |
| 76 | CNTBCONNECT BIOPHARMA HLDGS LTD | 450,000 | $10.9B | 164.44% | |
| 77 | JNCEEURJOUNCE THERAPEUTICS INC | 1,396,203 | $10.4B | 156.45% | |
| 78 | NYXHNYXOAH S A | 344,911 | $10.1B | 152.12% | |
| 79 | BMEABIOMEA FUSION INC | 830,794 | $9.9B | 148.95% | |
| 80 | —LIFESCI ACQUISITION II CORP | 975,000 | $9.6B | 144.10% | |
| 81 | —LA JOLLA PHARMACEUTICAL CO | 2,327,903 | $9.3B | 140.07% | |
| 82 | TNGXTANGO THERAPEUTICS INC | 600,000 | $7.8B | 117.00% | |
| 83 | PRCTPROCEPT BIOROBOTICS CORP | 194,136 | $7.4B | 111.69% | |
| 84 | MLTXHELIX ACQUISITION CORP | 750,000 | $7.4B | 111.42% | |
| 85 | CTMXCYTOMX THERAPEUTICS INC | 1,400,939 | $7.1B | 107.54% | |
| 86 | NAUTNAUTILUS BIOTECHNOLOGY INC | 1,100,000 | $6.6B | 99.35% | |
| 87 | —RESEARCH ALLIANCE CORP II | 637,000 | $6.3B | 94.62% | |
| 88 | —BCLS ACQUISITION CORP | 612,500 | $6.1B | 92.01% | |
| 89 | —ASLAN PHARMACEUTICALS LTD | 3,250,000 | $5.8B | 87.24% | |
| 90 | SRRKSCHOLAR ROCK HLDG CORP | 161,612 | $5.3B | 80.47% | |
| 91 | SOPHSOPHIA GENETICS SA | 300,000 | $5.3B | 79.31% | |
| 92 | BLIUSDBERKELEY LTS INC | 257,546 | $5.0B | 75.98% | |
| 93 | —SUMMIT HEALTHCRE ACQUISTN CO | 500,000 | $5.0B | 75.78% | |
| 94 | —ARYA SCIENCES ACQU CORP IV | 500,000 | $5.0B | 75.78% | |
| 95 | RCELAVITA MEDICAL INC | 280,000 | $5.0B | 74.83% | |
| 96 | —ARYA SCIENCES ACQUISITN CORP | 500,000 | $4.9B | 74.50% | |
| 97 | IMTXIMMATICS N.V | 350,000 | $4.5B | 68.62% | |
| 98 | AFIBACUTUS MED INC | 491,834 | $4.3B | 65.57% | |
| 99 | APVOAPTEVO THERAPEUTICS INC | 281,402 | $4.3B | 65.53% | |
| 100 | —5 01 ACQUISITION CORP | 392,000 | $3.8B | 58.05% |
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