Sio Capital Management, LLC
CIK: 0001482416Latest portfolio: $635.7M · Q4 2025
Holdings
68
Total Value
$635.7M
New Positions
27
Closed Positions
10
Top Holdings
View All 68 Holdings →| # | Stock | Shares | Value | % Portfolio | Change | Type |
|---|---|---|---|---|---|---|
| 1 | CELCCELCUITY INC | 477,067 | $47.6M | 7.48% | -309,459 | |
| 2 | CITHE CIGNA GROUP | 172,203 | $47.4M | 7.46% | NEW | |
| 3 | SNYSANOFI SA | 971,686 | $47.1M | 7.41% | +409K | |
| 4 | MMSMAXIMUS INC | 500,304 | $43.2M | 6.79% | -57,311 | |
| 5 | ZBHZIMMER BIOMET HOLDINGS INC | 385,642 | $34.7M | 5.45% | NEW | |
| 6 | RYTMRHYTHM PHARMACEUTICALS INC | 265,700 | $28.4M | 4.47% | NEW | Put |
| 7 | KVUEKENVUE INC | 1,465,442 | $25.3M | 3.98% | +621K | |
| 8 | OGNORGANON & CO | 3,421,765 | $24.5M | 3.86% | NEW | |
| 9 | ICLRICON PLC | 127,202 | $23.2M | 3.65% | NEW | |
| 10 | WAYWAYSTAR HLDG CORP | 613,725 | $20.1M | 3.16% | NEW | |
| 11 | LIVNLIVANOVA PLC | 322,382 | $19.8M | 3.12% | NEW | |
| 12 | DNTHDIANTHUS THERAPEUTICS INC | 474,503 | $19.6M | 3.08% | -103,247 | |
| 13 | BHVNBIOHAVEN LTD | 1,244,764 | $14.1M | 2.21% | NEW | |
| 14 | GPCRSTRUCTURE THERAPEUTICS INC | 201,500 | $14.0M | 2.20% | NEW | |
| 15 | TYRATYRA BIOSCIENCES INC | 526,002 | $13.8M | 2.18% | +11K | |
| 16 | BMRNBIOMARIN PHARMACEUTICAL INC | 232,688 | $13.8M | 2.18% | +8K | |
| 17 | BTSGBRIGHTSPRING HEALTH SVCS INC | 308,010 | $11.5M | 1.81% | NEW | |
| 18 | CNCCENTENE CORP DEL | 274,350 | $11.3M | 1.78% | -113,250 | |
| 19 | CRLCHARLES RIV LABS INTL INC | 54,985 | $11.0M | 1.73% | NEW | |
| 20 | TFXTELEFLEX INCORPORATED | 86,876 | $10.6M | 1.67% | +47K | |
| 21 | AVRANTERIS TECHNOLOGIES GLOBAL | 1,874,641 | $9.4M | 1.47% | +102K | |
| 22 | TARAPROTARA THERAPEUTICS INC | 1,715,394 | $9.1M | 1.44% | NEW | |
| 23 | XXYCROSS CTRY HEALTHCARE INC | 1,068,821 | $8.7M | 1.36% | NEW | |
| 24 | HAEHAEMONETICS CORP MASS | 92,631 | $7.4M | 1.17% | -105,404 | |
| 25 | BSFAANI PHARMACEUTICALS INC | 87,272 | $6.9M | 1.08% | +32K |
Quarterly Changes
New Positions
Increased Positions
Sector Breakdown
Healthcare0.0% ($4.7582473954708735e+234T)
Unknown0.0% ($865.8T)
Technology0.0% ($201.0M)
Industrials0.0% ($43.2M)
Consumer Defensive0.0% ($25.3M)
Consumer Cyclical0.0% ($5.4M)
Filing History
Fund Information
Sio Capital Management, LLC is an institutional investment manager that files 13F reports with the SEC. As of the Q4 2025 filing, the fund reported a portfolio valued at $635.7M across 68 holdings. The largest position is CELCUITY INC (CELC), representing 7.5% of the portfolio. Compared to the previous quarter, the fund opened 27 new positions and closed 10 positions. 13F filings are required quarterly disclosures that provide transparency into the holdings of institutional investment managers with at least $100 million in qualifying assets.