Sofinnova Investments, Inc. Q4 2024 Filing

Filed February 14, 2025

Portfolio Value

$1.4T

Holdings

60

Report Date

Q4 2024

Filing Type

13F-HR

All Holdings (60 positions)

#StockSharesValue% PortfolioType
1
NTRANatera Inc
1,550,280$245.4B17.88%
2
VERAVera Therapeutics Inc
2,793,987$118.2B8.61%
3
GILDGilead Sciences Inc
774,227$71.5B5.21%
4
ABBVAbbVie Inc
359,393$63.9B4.65%
5
JAZZJazz Pharmaceuticals PLC
504,193$62.1B4.52%
6
SRPTSarepta Therapeutics Inc
428,771$52.1B3.80%
7
AXSMAxsome Therapeutics Inc
591,726$50.1B3.65%Call
8
AVBPArrivent BioPharma Inc
1,696,752$45.2B3.29%
9
AZNAstraZeneca PLC
651,344$42.7B3.11%
10
SYKStryker Corporation
116,005$41.8B3.04%
11
REPLReplimune Group Inc
3,149,522$38.1B2.78%
12
INCYIncyte Corp
524,267$36.2B2.64%
13
RAPPRapport Therapeutics Inc
1,995,594$35.4B2.58%
14
SLNOSoleno Therapeutics Inc
757,248$34.0B2.48%
15
BSXBoston Scientific Corp
346,571$31.0B2.25%
16
IDYAIDEAYA Biosciences Inc
1,069,090$27.5B2.00%
17
ALNYAlnylam Pharmaceuticals Inc
110,157$25.9B1.89%
18
ALKSAlkermes Plc
894,266$25.7B1.87%
19
DYNDyne Therapeutics Inc
1,071,498$25.2B1.84%
20
DC4Dexcom Inc
290,210$22.6B1.64%
21
RYTMRhythm Pharmaceuticals Inc
397,428$22.2B1.62%
22
GMEDGlobus Med Inc
244,700$20.2B1.47%
23
ISRGIntuitive Surgical Inc
37,896$19.8B1.44%
24
IM8NInsmed Inc
256,281$17.7B1.29%
25
YMABUSDY-mAbs Therapeutics Inc
2,194,278$17.2B1.25%
26
YB4PSavara Inc
5,471,299$16.8B1.22%
27
JANXJanux Therapeutics Inc
253,262$13.6B0.99%
28
BIOABioAge Labs Inc
2,304,901$13.3B0.97%
29
INZYInozyme Pharma Inc
4,280,308$11.9B0.86%
30
LLYEli Lilly & Co
14,364$11.1B0.81%
31
EWTXEdgewise Therapeutics Inc
402,773$10.8B0.78%
32
PHVSPharvaris N V
560,723$10.7B0.78%
33
AVTEAerovate Therapeutics Inc
3,758,686$10.0B0.73%
34
NARIUSDInari Med Inc
180,456$9.2B0.67%
35
SNDXSyndax Pharmaceuticals Inc
658,627$8.7B0.63%
36
INBXInhibrx Biosciences Inc
527,190$8.1B0.59%
37
IMNMImmunome Inc
746,824$7.9B0.58%
38
COGTCogent Biosciences Inc
823,160$6.4B0.47%
39
SP4PAchieve Life Sciences Inc
1,306,482$4.6B0.33%
40
ERASErasca Inc
1,795,880$4.5B0.33%
41
ESTAEstablishment Labs Hldgs Inc
95,305$4.4B0.32%
42
AVTRAvantor Inc
200,000$4.2B0.31%
43
EWEdwards Lifesciences Corp
40,000$3.0B0.22%
44
EXASExact Sciences Corp
52,042$2.9B0.21%
45
IMTXImmatics N.V
343,206$2.4B0.18%
46
DHRDanaher Corporation
10,000$2.3B0.17%
47
NXTCNextcure Inc
2,671,856$2.1B0.15%
48
ANABAnaptysBio Inc
132,927$1.8B0.13%
49
KROSKeros Therapeutics Inc
95,375$1.5B0.11%
50
BOLT1EURBolt Biotherapeutics Inc
2,754,437$1.5B0.11%
51
IRONDisc Medicine Inc
22,752$1.4B0.11%
52
BDXBecton Dickinson & Co
4,951$1.1B0.08%
53
VIRVir Biotechnology Inc
114,131$837.7M0.06%
54
ICUIICU Med Inc
5,000$775.9M0.06%
55
ELVNEnliven Therapeutics Inc
34,025$765.6M0.06%
56
Ikena Oncology Inc
382,616$627.5M0.05%
57
TVTXTravere Therapeutics Inc
32,616$568.2M0.04%
58
GPCRStructure Therapeutics Inc
20,892$566.6M0.04%
59
LUNGPulmonx Corp
61,326$416.4M0.03%
60
RNAAvidity Biosciences Inc
13,789$401.0M0.03%