VR Adviser, LLC
CIK: 0001615982Latest portfolio: $2.0B · Q4 2025
Holdings
27
Total Value
$2.0B
New Positions
1
Closed Positions
6
Top Holdings
View All 27 Holdings →| # | Stock | Shares | Value | % Portfolio | Change | Type |
|---|---|---|---|---|---|---|
| 1 | APGEAPOGEE THERAPEUTICS INC | 8,493,321 | $641.1M | 31.67% | — | |
| 2 | ORKAORUKA THERAPEUTICS INC | 4,148,428 | $125.7M | 6.21% | — | |
| 3 | VRDNVIRIDIAN THERAPEUTICS INC | 3,882,709 | $120.8M | 5.97% | — | |
| 4 | SYRESPYRE THERAPEUTICS INC | 3,685,448 | $120.7M | 5.96% | +1.0M | |
| 5 | KALVKALVISTA PHARMACEUTICALS INC | 6,728,985 | $108.7M | 5.37% | — | |
| 6 | OCULOCULAR THERAPEUTIX INC | 7,315,547 | $88.8M | 4.39% | -5,845,915 | |
| 7 | YB4PSAVARA INC | 13,740,375 | $82.9M | 4.09% | +1.1M | |
| 8 | COGTCOGENT BIOSCIENCES INC | 2,000,000 | $71.0M | 3.51% | -2,000,000 | |
| 9 | ERASERASCA INC | 17,857,083 | $66.4M | 3.28% | — | |
| 10 | CTMXCYTOMX THERAPEUTICS INC | 15,561,500 | $66.3M | 3.27% | — | |
| 11 | MAZEMAZE THERAPEUTICS INC | 1,548,569 | $64.2M | 3.17% | +318K | |
| 12 | JBIOJADE BIOSCIENCES INC | 3,220,364 | $49.7M | 2.45% | — | |
| 13 | ELVNENLIVEN THERAPEUTICS INC | 3,226,331 | $49.7M | 2.45% | — | |
| 14 | ORICORIC PHARMACEUTICALS INC | 5,676,230 | $46.4M | 2.29% | -920,655 | |
| 15 | ENGNENGENE HOLDINGS INC | 4,771,414 | $43.1M | 2.13% | -275,000 | |
| 16 | DYNDYNE THERAPEUTICS INC | 2,173,913 | $42.5M | 2.10% | — | |
| 17 | DNTHDIANTHUS THERAPEUTICS INC | 1,000,000 | $41.2M | 2.04% | +39K | |
| 18 | UPBUPSTREAM BIO INC | 1,169,298 | $31.7M | 1.57% | — | |
| 19 | HELPCYBIN INC | 3,840,250 | $31.4M | 1.55% | NEW | |
| 20 | ZURAZURA BIO LTD | 5,345,115 | $28.0M | 1.38% | +714K | |
| 21 | VORVOR BIOPHARMA INC | 1,943,766 | $25.4M | 1.26% | +1.4M | |
| 22 | CBIOCRESCENT BIOPHARMA INC. | 2,133,576 | $25.3M | 1.25% | +746K | |
| 23 | SEPNSEPTERNA INC | 610,808 | $17.0M | 0.84% | — | |
| 24 | SRZNSURROZEN INC | 632,931 | $14.3M | 0.71% | — | |
| 25 | CGEMCULLINAN THERAPEUTICS INC | 1,379,965 | $14.3M | 0.71% | — |
Quarterly Changes
New Positions
- HELPNEW$31.4M
Sector Breakdown
Healthcare0.0% ($6.410751257381208e+119T)
Unknown0.0% ($82.9B)
Filing History
| Quarter | Filing Date | Portfolio Value | Holdings |
|---|---|---|---|
| Q4 2025 | Feb 17, 2026 | $2.0B | 27 |
| Q3 2025 | Nov 14, 2025 | $1.8T | 33 |
| Q2 2025 | Aug 14, 2025 | $1.3T | 31 |
| Q1 2025 | May 15, 2025 | $1.2T | 37 |
| Q4 2024 | Feb 14, 2025 | $1.5T | 37 |
| Q3 2024 | Nov 14, 2024 | $1909.3T | 38 |
| Q2 2024 | Aug 14, 2024 | $1570.2T | 35 |
| Q1 2024 | May 15, 2024 | $2102.2T | 38 |
| Q4 2023 | Feb 14, 2024 | $1458.1T | 36 |
| Q3 2023 | Nov 14, 2023 | $949.9T | 37 |
| Q2 2023 | Aug 11, 2023 | $625.4T | 30 |
| Q1 2023 | May 15, 2023 | $512.2T | 25 |
| Q4 2022 | Feb 14, 2023 | $622.9T | 29 |
| Q3 2022 | Nov 14, 2022 | $680.6B | 32 |
| Q2 2022 | Aug 15, 2022 | $554.1B | 28 |
| Q1 2022 | May 16, 2022 | $617.2B | 27 |
| Q4 2021 | Feb 14, 2022 | $731.5B | 26 |
| Q3 2021 | Nov 15, 2021 | $778.5B | 26 |
| Q2 2021 | Aug 13, 2021 | $824.4B | 29 |
| Q1 2021 | May 14, 2021 | $921.8B | 28 |
| Q4 2020 | Feb 12, 2021 | $680.1B | 25 |
| Q3 2020 | Nov 16, 2020 | $511.2B | 22 |
| Q2 2020 | Aug 14, 2020 | $417.6B | 16 |
| Q1 2020 | May 15, 2020 | $369.2B | 16 |
Fund Information
VR Adviser, LLC is an institutional investment manager that files 13F reports with the SEC. As of the Q4 2025 filing, the fund reported a portfolio valued at $2.0B across 27 holdings. The largest position is APOGEE THERAPEUTICS INC (APGE), representing 31.7% of the portfolio. Compared to the previous quarter, the fund opened 1 new positions and closed 7 positions. 13F filings are required quarterly disclosures that provide transparency into the holdings of institutional investment managers with at least $100 million in qualifying assets.