Sofinnova Investments, Inc. Q4 2020 Filing

Filed February 16, 2021

Portfolio Value

$1.7T

Holdings

66

Report Date

Q4 2020

Filing Type

13F-HR

All Holdings (66 positions)

#StockSharesValue% PortfolioType
1
NTRANatera
3,100,560$308.6B18.37%
2
KRTXKaruna Therapeutics, Inc.
1,952,441$198.3B11.81%
3
ASNDAscendis Pharma A/S
1,109,874$185.1B11.02%
4
YMABUSDY-mAbs Therapeutics, Inc
2,194,278$108.6B6.47%
5
UTHUnited Therapeutics Corp
347,901$52.8B3.14%
6
Checkmate Pharmaceuticals Inc
3,606,707$52.6B3.13%
7
AZNAstraZeneca PLC
842,600$42.1B2.51%
8
INZYInozyme Pharma, Inc.
2,028,308$41.9B2.49%
9
AMGNAmgen Inc
164,663$37.9B2.25%
10
JAZZJazz Pharmaceuticals PLC
212,911$35.1B2.09%
11
XLVHealth Care Select Sector SPDR
300,000$34.0B2.03%Put
12
GRTXGalera Therapeutics, Inc
3,083,712$31.5B1.88%
13
ABBVAbbvie Inc
293,596$31.5B1.87%
14
Akouos, Inc
1,515,074$30.0B1.79%
15
Nextcure, Inc
2,671,856$29.1B1.73%
16
ITCIEURIntra-Cellular Therapies Inc
848,162$27.0B1.61%
17
IWMiShares Russell 2000 ETF
130,000$25.5B1.52%Put
18
Nucana Biomed Ltd
5,599,999$25.1B1.50%
19
MRUSMerus N.V.
1,311,039$23.0B1.37%
20
PTCTPTC Therapeutics Inc
316,478$19.3B1.15%
21
RETAEURReata Pharmaceuticals Inc
148,937$18.4B1.10%
22
Athira Pharma, Inc.
509,168$17.4B1.04%
23
OTICEUROtonomy Inc
2,620,668$17.0B1.01%
24
HZNPHorizon Therapeutics PLC
213,390$15.6B0.93%
25
PTGXProtagonist Therapeutics Inc
724,904$14.6B0.87%
26
BMRNBiomarin Pharmaceutical Inc
164,545$14.4B0.86%
27
ACRSAclaris Therapeutics
1,911,573$12.4B0.74%
28
RGNXRegenxbio Inc
271,114$12.3B0.73%
29
GW Pharmaceuticals PLC
100,762$11.6B0.69%
30
Nucana Biomed Ltd
2,400,000$10.8B0.64%
31
CYTKCytokinetics Inc
508,394$10.6B0.63%
32
MGNXMacroGenics Inc
458,807$10.5B0.62%
33
TCR2 Therapeutics Inc
333,707$10.3B0.61%
34
IM8NInsmed Inc
309,662$10.3B0.61%
35
ObsEva SA
4,749,623$9.9B0.59%
36
ARNAEURArena Pharmaceuticals Inc
121,373$9.3B0.56%
37
SRPTSarepta Therapeutics Inc
51,848$8.8B0.53%
38
ACADACADIA Pharmaceuticals Inc
164,625$8.8B0.52%
39
BCRXBioCryst Pharmaceuticals Inc
1,122,800$8.4B0.50%
40
SNDXSyndax Pharmaceuticals Inc
372,909$8.3B0.49%
41
MIRMMirum Pharmaceuticals Inc
454,974$7.9B0.47%
42
CHRSCoherus BioSciences
434,555$7.6B0.45%
43
CCXIEURChemoCentryx Inc
113,213$7.0B0.42%
44
JNCEEURJounce Therapeutics Inc
925,280$6.5B0.39%
45
PBYIPuma Biotechnology Inc
629,650$6.5B0.38%
46
LLYEli Lilly and Co
36,909$6.2B0.37%
47
AMRNAmarin Corp
1,170,584$5.7B0.34%
48
ALGSAligos Therapeutics Inc
191,061$5.3B0.31%
49
Calithera Biosciences Inc
1,075,326$5.3B0.31%Put
50
RCUSArcus Biosciences Inc
186,278$4.8B0.29%
51
XLRNAcceleron Pharma Inc
36,688$4.7B0.28%
52
IOVAIovance Biotherapeutics Inc
100,000$4.6B0.28%Put
53
Aptose Biosciences Inc
981,135$4.3B0.26%
54
1K0IGM Biosciences Inc
45,131$4.0B0.24%
55
KURAKura Oncology Inc
120,677$3.9B0.23%
56
TGTXTG Therapeutics Inc
65,474$3.4B0.20%
57
MRNS*Marinus Pharmaceuticals Inc
274,027$3.3B0.20%
58
IMTXImmatics NV
279,532$3.0B0.18%
59
Zogenix Inc
89,579$1.8B0.11%
60
Synlogic Inc.
574,972$1.2B0.07%
61
FATEFate Therapeutics Inc
13,497$1.2B0.07%
62
Kadmon Holdings Inc
228,893$950.0M0.06%
63
REPLReplimune Group Inc
20,000$763.0M0.05%
64
LQDALiquidia Corp
147,744$436.0M0.03%
65
PDSBPDS Biotechnology Corporation
142,635$305.0M0.02%
66
BCABBioatla Inc
3,000$102.0M0.01%