Sofinnova Investments, Inc. Q2 2022 Filing

Filed August 15, 2022

Portfolio Value

$1.2T

Holdings

56

Report Date

Q2 2022

Filing Type

13F-HR

All Holdings (56 positions)

#StockSharesValue% PortfolioType
1
KRTXKaruna Therapeutics Inc
2,073,124$262.3B21.84%
2
NTRANatera Inc
3,102,960$110.0B9.16%
3
Cincor Pharma Inc
5,573,949$105.0B8.75%
4
AVTEAerovate Therapeutics Inc
3,758,686$58.7B4.89%
5
ASNDAscendis Pharma A/S
499,824$46.5B3.87%
6
VERAVera Therapeutics Inc
3,181,442$43.3B3.61%
7
XLVHealth Care Select Sector SPDR Fund
300,000$38.5B3.20%Put
8
YMABUSDY-mAbs Therapeutics Inc
2,194,278$33.2B2.76%
9
MRKMerck & Co Inc
360,961$32.9B2.74%
10
NVONovo-Nordisk A S
273,873$30.5B2.54%
11
XBISPDR S&P Biotech ETF
400,000$29.7B2.47%Put
12
UTHUnited Therapeutics Corp
106,379$25.1B2.09%
13
BMRNBiomarin Pharmaceutical Inc
301,605$25.0B2.08%
14
RETAEURReata Pharmaceuticals Inc
783,851$23.8B1.98%
15
CCXIEURChemoCentryx Inc
886,659$22.0B1.83%Call
16
VRTXVertex Pharmaceuticals Inc
74,758$21.1B1.75%
17
AZNAstraZeneca PLC
316,360$20.9B1.74%
18
RGNXRegenxbio Inc
776,624$19.2B1.60%
19
INZYInozyme Pharm Inc
3,655,308$17.4B1.45%
20
CTIC1USDCTI Biopharma Corp
2,704,510$16.1B1.34%
21
IRTCiRhythm Technologies Inc
142,091$15.3B1.28%
22
SNYSanofi SA
282,200$14.1B1.18%
23
DC4Dexcom Inc
189,092$14.1B1.17%
24
CYTKCytokinetics Inc
320,780$12.6B1.05%
25
NXTCNextcure Inc
2,671,856$12.6B1.05%
26
IMTXImmatics NV
1,294,103$11.3B0.94%
27
Prometheus Biosciences Inc
386,395$10.9B0.91%
28
SRPTSarepta Therapeutics Inc
131,245$9.8B0.82%
29
ZNTLZentalis Pharmaceuticals Inc
328,397$9.2B0.77%
30
HZNPHorizon Therapeutics PLC
100,297$8.0B0.67%
31
SNDXSyndax Pharmaceuticals Inc
413,428$8.0B0.66%
32
ObsEva SA
4,749,623$7.6B0.64%
33
TORCEURAdicet Bio Inc
518,379$7.6B0.63%
34
Akouos Inc
1,515,074$7.1B0.59%
35
OPHTEURIveric Bio Inc
653,047$6.3B0.52%
36
GONGeron Corp
3,791,630$5.9B0.49%Call
37
ARGXargenx SE
15,000$5.7B0.47%
38
BOLT1EURBolt Biotherapeutics Inc
2,754,437$5.6B0.47%
39
TVTXTravere Therapeutics Inc
212,593$5.2B0.43%
40
IMGNEURImmunoGen Inc
1,140,788$5.1B0.43%
41
SGENUSDSeagen Inc
27,894$4.9B0.41%
42
290AChinook Therapeutics Inc
276,609$4.8B0.40%
43
XNCRXencor Inc
158,164$4.3B0.36%
44
Nucana Biomed
5,599,999$4.1B0.34%
45
GRTXGalera Therapeutics Inc
3,083,712$4.0B0.33%
46
AMLXAmylyx Pharmaceuticals Inc
187,381$3.6B0.30%
47
JNCEEURJounce Therapeutics Inc
981,928$3.0B0.25%
48
AGENEURAgenus Inc
952,742$1.8B0.15%
49
Nucana Biomed
2,400,000$1.7B0.14%
50
INBXUSDInhibrx Inc
147,935$1.7B0.14%
51
TCE2Celldex Therapeutics Inc
48,304$1.3B0.11%
52
PTGXProtagonist Therapeutics Inc
100,000$791.0M0.07%Call
53
Synlogic Inc
574,972$661.0M0.06%
54
PDSBPDS Biotechnology Corporation
142,635$521.0M0.04%
55
Fusion Pharmaceuticals Inc
78,066$194.0M0.02%
56
IM8NInsmed Inc
7,370$145.0M0.01%