Sofinnova Investments, Inc. Q1 2023 Filing

Filed May 11, 2023

Portfolio Value

$1.6T

Holdings

51

Report Date

Q1 2023

Filing Type

13F-HR

All Holdings (51 positions)

#StockSharesValue% PortfolioType
1
KRTXKaruna Therapeutics Inc
1,773,124$322.1B20.60%
2
NTRANatera Inc
3,100,560$172.1B11.01%
3
MRKMerck & Co Inc
841,522$89.5B5.73%
4
SPYSPDR S&P 500 ETF Trust
200,000$81.9B5.24%Put
5
ASNDAscendis Pharma A/S
754,032$80.8B5.17%
6
AVTEAerovate Therapeutics Inc
3,758,686$75.8B4.85%
7
RETAEURReata Pharmaceuticals Inc
627,683$57.1B3.65%
8
LLYEli Lilly and Co
137,100$47.1B3.01%
9
HZNPHorizon Therapeutics PLC
408,819$44.6B2.85%
10
ISRGIntuitive Surgical Inc
149,589$38.2B2.44%
11
BIIBBiogen Inc
132,600$36.9B2.36%
12
BMRNBiomarin Pharmaceutical Inc
359,035$34.9B2.23%
13
DC4Dexcom Inc
257,227$29.9B1.91%
14
TVTXTravere Therapeutics Inc
1,263,721$28.4B1.82%
15
VERAVera Therapeutics Inc
3,467,156$26.9B1.72%
16
PTCTPTC Therapeutics Inc
517,095$25.0B1.60%
17
ZNTLZentalis Pharmaceuticals Inc
1,439,062$24.8B1.58%
18
INBXUSDInhibrx Inc
1,244,488$23.5B1.50%
19
290AChinook Therapeutics Inc
1,002,348$23.2B1.48%
20
SNDXSyndax Pharmaceuticals Inc
1,075,424$22.7B1.45%
21
OPHTEURIVERIC bio Inc
905,982$22.0B1.41%
22
IMTXImmatics NV
3,132,694$21.6B1.38%
23
INZYInozyme Pharma Inc
3,655,308$20.9B1.34%
24
GONGeron Corp
8,274,892$18.0B1.15%
25
SRPTSarepta Therapeutics Inc
119,065$16.4B1.05%
26
EX9Exelixis Inc
831,243$16.1B1.03%
27
VIRVir Biotechnology Inc
657,559$15.3B0.98%
28
TCE2Celldex Therapeutics Inc
419,397$15.1B0.97%
29
Prometheus Biosciences Inc
123,842$13.3B0.85%
30
CYTKCytokinetics Inc
353,796$12.5B0.80%
31
CTIC1USDCTI Biopharma Corp
2,794,542$11.7B0.75%
32
YMABUSDY-mAbs Therapeutics Inc
2,194,278$11.0B0.70%
33
AGENEURAgenus Inc
6,407,457$9.7B0.62%
34
MRNS*Marinus Pharmaceuticals Inc
1,200,389$8.3B0.53%
35
GRTXGalera Therapeutics Inc
3,083,712$7.9B0.50%
36
KURAKura Oncology Inc
616,169$7.5B0.48%
37
AXSMAxsome Therapeutics Inc
120,896$7.5B0.48%
38
IMGNEURImmunoGen Inc
1,924,532$7.4B0.47%Call
39
IDYAIDEAYA Biosciences Inc
453,149$6.2B0.40%
40
Nucana PLC
5,599,999$5.4B0.34%
41
RVMDRevolution Medicines Inc
183,838$4.0B0.25%
42
NXTCNextcure Inc
2,671,856$4.0B0.25%
43
BOLT1EURBolt Biotherapeutics Inc
2,754,437$3.8B0.24%
44
KROSKeros Therapeutics Inc
77,100$3.3B0.21%
45
NVCRNovocure Ltd
50,000$3.0B0.19%Call
46
Nucana PLC
2,400,000$2.3B0.15%
47
bluebird bio Inc
672,815$2.1B0.14%
48
PDSBPDS Biotechnology Corp
142,635$877.2M0.06%
49
Fusion Pharmaceuticals Inc
117,099$441.5M0.03%
50
Synlogic Inc
574,972$363.4M0.02%
51
ALNYAlnylam Pharmaceuticals Inc
448$89.7M0.01%