Avidity Partners Management LP
CIK: 0001791827Latest portfolio: $346.7M · Q4 2025
Holdings
39
Total Value
$346.7M
New Positions
11
Closed Positions
15
Top Holdings
View All 39 Holdings →| # | Stock | Shares | Value | % Portfolio | Change | Type |
|---|---|---|---|---|---|---|
| 1 | DNTHDIANTHUS THERAPEUTICS INC | 2,104,184 | $86.7M | 25.01% | -1,100,000 | |
| 2 | CGONCG ONCOLOGY INC | 1,472,699 | $61.1M | 17.64% | -128,200 | |
| 3 | JBIOJADE BIOSCIENCES INC | 1,400,708 | $21.6M | 6.23% | +274K | |
| 4 | ORKAORUKA THERAPEUTICS INC | 660,424 | $20.0M | 5.77% | — | |
| 5 | TEVATEVA PHARMACEUTICAL INDS LTD | 417,300 | $13.0M | 3.76% | -92,700 | |
| 6 | BSXBOSTON SCIENTIFIC CORP | 114,500 | $10.9M | 3.15% | -49,800 | |
| 7 | MDTMEDTRONIC PLC | 107,600 | $10.3M | 2.98% | -83,000 | |
| 8 | CATXPERSPECTIVE THERAPEUTICS INC | 3,210,733 | $8.8M | 2.55% | +217K | |
| 9 | ALNYALNYLAM PHARMACEUTICALS INC | 21,000 | $8.3M | 2.41% | NEW | |
| 10 | RGENREPLIGEN CORP | 50,300 | $8.2M | 2.38% | +27K | |
| 11 | CNTXCONTEXT THERAPEUTICS INC | 5,504,855 | $8.1M | 2.33% | -3,477,000 | |
| 12 | MCKMCKESSON CORP | 9,520 | $7.8M | 2.25% | +4K | |
| 13 | ICLRICON PLC | 33,100 | $6.0M | 1.74% | NEW | |
| 14 | AG8AGILENT TECHNOLOGIES INC | 41,500 | $5.6M | 1.63% | NEW | |
| 15 | PFEPFIZER INC | 203,600 | $5.1M | 1.46% | -162,800 | |
| 16 | CNCCENTENE CORP DEL | 119,400 | $4.9M | 1.42% | NEW | |
| 17 | KVUEKENVUE INC | 232,800 | $4.0M | 1.16% | -32,400 | |
| 18 | DHRDANAHER CORPORATION | 17,000 | $3.9M | 1.12% | -37,700 | |
| 19 | TMOTHERMO FISHER SCIENTIFIC INC | 6,700 | $3.9M | 1.12% | -12,200 | |
| 20 | NVONOVO-NORDISK A S | 67,300 | $3.4M | 0.99% | NEW | |
| 21 | PHATPHATHOM PHARMACEUTICALS INC | 206,076 | $3.4M | 0.99% | -99,924 | |
| 22 | EHCENCOMPASS HEALTH CORP | 31,600 | $3.4M | 0.97% | -10,300 | |
| 23 | CITHE CIGNA GROUP | 11,600 | $3.2M | 0.92% | -5,000 | |
| 24 | ABGCENCORA INC | 9,400 | $3.2M | 0.92% | -9,600 | |
| 25 | IM8NINSMED INC | 17,700 | $3.1M | 0.89% | +6K |
Quarterly Changes
New Positions
Increased Positions
Sector Breakdown
Healthcare0.0% ($8.671361146216123e+131T)
Unknown0.0% ($56.5B)
Consumer Defensive0.0% ($4.0M)
Consumer Cyclical0.0% ($3.2M)
Financial Services0.0% ($765K)
Filing History
Fund Information
Avidity Partners Management LP is an institutional investment manager that files 13F reports with the SEC. As of the Q4 2025 filing, the fund reported a portfolio valued at $346.7M across 39 holdings. The largest position is DIANTHUS THERAPEUTICS INC (DNTH), representing 25.0% of the portfolio. Compared to the previous quarter, the fund opened 11 new positions and closed 15 positions. 13F filings are required quarterly disclosures that provide transparency into the holdings of institutional investment managers with at least $100 million in qualifying assets.