Who Owns Xeris Biopharma Holdings, Inc. (XERS)?Hedge Fund & Institutional Holders

$5.46-0.01 (-0.27%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$7.730261000540006e+208T

% of Float Held

Infinity%

QoQ Change in Holders

+13 / -0

Price History

$2.51$4.36$6.21$8.05$9.90Sep 24Jun 25Mar 26

XERS — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
Ishara Investments LPNew Position+800K+$6.3M
FEDERATED HERMES, INC.New Position+855K+$6.0M
NORGES BANKNew Position+801K+$6.0M
ESSEX INVESTMENT MANAGEMENT CO LLCNew Position+735K+$5.8M
Point72 Asset Management, L.P.New Position+608K+$4.0M
ALGERT GLOBAL LLCIncreased+561K+$3.7M
CASTLEARK MANAGEMENT LLCNew Position+446K+$3.0M
Bank of New York Mellon CorpNew Position+434K+$3.0M
Apella Capital, LLCNew Position+246K+$1.9M
HRT FINANCIAL LPIncreased+260K+$1.4M
PRINCIPAL FINANCIAL GROUP INCNew Position+151K+$1.2M
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPNew Position+215K+$1.0M
COMMONWEALTH EQUITY SERVICES, LLCNew Position+198K+$1.0M
SG Americas Securities, LLCNew Position+110K+$865K
Faithward Advisors, LLCNew Position+107K+$837K

XERS — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
CAPSTONE INVESTMENT ADVISORS, LLCDecreased-17K-$62.1B
MORGAN STANLEYDecreased-512K-$26.2B
Nuveen, LLCDecreased-21K-$23.0B
GOLDMAN SACHS GROUP INCDecreased-227K-$14.6B
Parkman Healthcare Partners LLCDecreased-100K-$14.6B
UBS Group AGDecreased-1.2M-$14.5B
Connor, Clark & Lunn Investment Management Ltd.Decreased-640K-$13.8B
RENAISSANCE TECHNOLOGIES LLCDecreased-1.0M-$13.2B
BANK OF AMERICA CORP /DE/Decreased-877K-$13.0B
DEUTSCHE BANK AG\Decreased-627K-$12.8B
CHARLES SCHWAB INVESTMENT MANAGEMENT INCDecreased-43K-$11.8B
PRUDENTIAL FINANCIAL INCDecreased-815K-$11.7B
VOLORIDGE INVESTMENT MANAGEMENT, LLCDecreased-223K-$8.4B
Knott David M JrDecreased-45K-$8.3B
AQR CAPITAL MANAGEMENT LLCDecreased-26K-$8.0B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1VANGUARD GROUP INC9,847,450$77.3M0.00%Share
2CAPSTONE INVESTMENT ADVISORS, LLC23,074,000$61.0M0.12%Share
3D. E. Shaw & Co., Inc.6,992,861$54.0M0.03%Share
4BlackRock, Inc.6,391,917$50.0M0.00%Share
5BlackRock, Inc.4,578,964$35.0M0.00%Share
6STATE STREET CORP4,116,924$32.0M0.00%Share
7GEODE CAPITAL MANAGEMENT, LLC3,750,851$29.0M0.00%Share
8Polar Asset Management Partners Inc.10,500,000$27.0M0.34%Share
9Qube Research & Technologies Ltd3,498,197$27.0M0.03%Share
10DRIEHAUS CAPITAL MANAGEMENT LLC2,980,567$23.4M0.16%Share
11MORGAN STANLEY2,238,561$17.0M0.00%Share
12Rosalind Advisors, Inc.2,111,700$16.6M5.83%Share
13Nuveen, LLC2,082,382$16.0M0.00%Share
14Parkman Healthcare Partners LLC1,691,585$13.3M1.26%Share
15TWO SIGMA INVESTMENTS, LP1,732,667$13.0M0.02%Share
16CHARLES SCHWAB INVESTMENT MANAGEMENT INC1,403,824$11.0M0.00%Share
17Legal & General Group Plc1,358,733$10.0M0.00%Share
18CenterBook Partners LP1,391,590$10.0M0.49%Share
19Granahan Investment Management, LLC1,223,404$9.6M0.41%Share
20KENNEDY CAPITAL MANAGEMENT LLC1,213,969$9.5M0.20%Share
21NORTHERN TRUST CORP1,264,887$9.0M0.00%Share
22VANGUARD GROUP INC1,111,781$8.7M0.00%Share
23GOLDMAN SACHS GROUP INC1,142,894$8.0M0.00%Share
24Connor, Clark & Lunn Investment Management Ltd.1,058,692$8.0M0.02%Share
25WELLINGTON MANAGEMENT GROUP LLP1,063,657$8.0M0.00%Share
26Knott David M Jr970,000$7.6M3.53%Share
27AQR CAPITAL MANAGEMENT LLC943,271$7.0M0.00%Share
28WELLINGTON MANAGEMENT GROUP LLP987,531$7.0M0.00%Share
29DEUTSCHE BANK AG\937,707$7.0M0.00%Share
30ACADIAN ASSET MANAGEMENT LLC971,598$7.0M0.01%Share
31Ishara Investments LP800,000$6.3M7.18%Share
32MILLENNIUM MANAGEMENT LLC859,051$6.0M0.00%Share
33TWO SIGMA ADVISERS, LP849,334$6.0M0.01%Share
34VOLORIDGE INVESTMENT MANAGEMENT, LLC811,129$6.0M0.02%Share
35FEDERATED HERMES, INC.854,888$6.0M0.01%Share
36NORGES BANK800,700$6.0M0.00%Share
37ESSEX INVESTMENT MANAGEMENT CO LLC734,532$5.8M0.88%Share
38ALGERT GLOBAL LLC718,844$5.0M0.08%Share
39BANK OF AMERICA CORP /DE/639,509$5.0M0.00%Share
40UBS Group AG564,713$4.4M0.00%Share
41BlackRock, Inc.555,783$4.0M0.00%Share
42D. E. Shaw & Co., Inc.581,989$4.0M0.00%Share
43PRUDENTIAL FINANCIAL INC519,149$4.0M0.00%Share
44JPMORGAN CHASE & CO543,940$4.0M0.00%Share
45GEODE CAPITAL MANAGEMENT, LLC525,138$4.0M0.00%Share
46RENAISSANCE TECHNOLOGIES LLC619,660$4.0M0.01%Share
47Nuveen, LLC635,342$4.0M0.00%Share
48Point72 Asset Management, L.P.608,080$4.0M0.00%Share
49HEALTHCARE OF ONTARIO PENSION PLAN TRUST FUND537,483$4.0M0.01%Share
50SEI INVESTMENTS CO397,204$3.0M0.00%Share

XERS Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025229$815.2M+47
Q3 2025182$840.8B+15
Q2 2025167$386.4B-35
Q1 2025202$533.5B+49
Q4 2024153$964.6B+34
Q3 2024119$113.7T+1
Q2 2024118$56.5T-1
Q1 2024119$57.2T—

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As of Q4 2025, 50 institutional investors hold XERS (Xeris Biopharma Holdings, Inc.). The largest holder is VANGUARD GROUP INC with $77.3M in shares. This quarter, 13 institutions opened new positions and 0 closed their positions.

Frequently Asked Questions

How many hedge funds own XERS?

As of Q4 2025, 50 institutional investors report holding XERS (Xeris Biopharma Holdings, Inc.) in their 13F filings.

Who is the largest institutional holder of XERS?

The largest institutional holder of XERS is VANGUARD GROUP INC with $77.3M in shares.

Is institutional ownership of XERS increasing or decreasing?

This quarter, 13 institutions opened new positions in XERS and 0 closed their positions.