Sofinnova Investments, Inc. Q1 2020 Filing

Filed May 13, 2020

Portfolio Value

$1.1T

Holdings

64

Report Date

Q1 2020

Filing Type

13F-HR

All Holdings (64 positions)

#StockSharesValue% PortfolioType
1
KRTXKaruna Therapeutics, Inc.
1,885,602$135.8B12.56%
2
ASNDAscendis Pharma A/S
1,109,874$125.0B11.56%
3
NXTCNextcure, Inc
2,671,856$99.0B9.16%
4
NTRANatera
3,100,560$92.6B8.56%
5
Principia Biopharma
1,417,258$84.2B7.78%
6
YMABUSDY-mAbs Therapeutics, Inc
2,194,278$57.3B5.30%
7
MRKMerck & Co Inc
463,795$35.7B3.30%
8
CHRSCoherus BioSciences
1,933,221$31.4B2.90%
9
GRTXGalera Therapeutics, Inc
3,083,712$29.3B2.71%
10
ALXNAlexion Pharmaceuticals Inc
307,300$27.6B2.55%
11
MRUSMerus N.V.
1,961,039$23.7B2.19%
12
UTHUnited Therapeutics Corp
233,559$22.1B2.05%
13
AMRNAmarin
5,208,305$20.8B1.93%
14
VRTXVertex Pharmaceuticals Inc
85,664$20.4B1.89%
15
BMRNBiomarin Pharmaceutical Inc
240,046$20.3B1.88%
16
BIIBBiogen Inc
52,628$16.6B1.54%
17
XLRNAcceleron Pharma Inc
165,160$14.8B1.37%
18
KNSAKiniksa Pharmaceuticals, Ltd
922,700$14.3B1.32%
19
Nucana Biomed Ltd
2,400,000$14.0B1.29%
20
Nucana Biomed Ltd
2,266,666$13.2B1.22%
21
PTCTPTC Therapeutics Inc
292,217$13.0B1.21%
22
ObsEva SA
4,749,623$11.4B1.06%
23
SRPTSarepta Therapeutics Inc
101,603$9.9B0.92%
24
KALAKala Pharmaceuticals Inc
1,114,520$9.8B0.91%
25
MyoKardia Inc
175,118$8.2B0.76%
26
AFWAlign Technology Inc
46,500$8.1B0.75%
27
GILDGilead Sciences Inc
100,000$7.5B0.69%Call
28
Kala Pharmaceuticals Inc
737,300$6.5B0.60%Put
29
Kadmon Holdings Inc
1,526,178$6.4B0.59%
30
Chiasma
1,630,221$6.0B0.55%
31
MIRMMirum Pharmaceuticals Inc
418,589$5.9B0.54%
32
HRTXHeron Therapeutics Inc
481,608$5.7B0.52%
33
PBYIPuma Biotechnology Inc
638,026$5.4B0.50%
34
AM6Amicus Therapeutics Inc
525,530$4.9B0.45%
35
ITRMIterum Therapeutics
1,726,514$4.7B0.43%
36
IOVAIovance Biotherapeutics Inc
150,000$4.5B0.42%Call
37
AXSMAxsome Therapeutics Inc
73,163$4.3B0.40%
38
ABBVAbbvie Inc
50,000$3.8B0.35%
39
2L9Blueprint Medicines Corp
63,100$3.7B0.34%
40
Calithera Biosciences Inc
819,002$3.6B0.34%
41
FIXXEURHomology Medicines Inc
230,663$3.6B0.33%
42
Applied Genetic Technologies Corp
1,062,615$3.5B0.32%
43
Akero Therapeutics Inc
150,000$3.2B0.29%Put
44
AKROAkero Therapeutics Inc
148,415$3.1B0.29%
45
Entasis Therapeutics Holdings Inc.
1,180,178$3.1B0.29%
46
OTICEUROtonomy Inc
1,515,629$3.0B0.28%
47
ALNYAlnylam Pharmaceuticals Inc
27,100$2.9B0.27%Call
48
TGTXTG Therapeutics Inc
275,305$2.7B0.25%
49
CCXIEURChemoCentryx Inc
66,695$2.7B0.25%
50
RIGLUSDRigel Pharmaceuticals Inc
1,446,318$2.3B0.21%
51
PTCTPTC Therapeutics Inc
50,000$2.2B0.21%Call
52
CGENCompugen Ltd
300,000$2.2B0.20%
53
SG7SAGE Therapeutics Inc
74,430$2.1B0.20%
54
ACRSAclaris Therapeutics
1,911,573$2.0B0.18%
55
Zymeworks Inc
49,989$1.8B0.16%
56
BCRXBioCryst Pharmaceuticals Inc
815,690$1.6B0.15%
57
Menlo Therapeutics Inc
604,829$1.6B0.15%
58
APLSApellis Pharmaceuticals, Inc
49,580$1.3B0.12%
59
Mersana Therapeutics Inc
225,000$1.3B0.12%
60
Synlogic Inc.
574,972$989.0M0.09%
61
Zogenix Inc
32,983$816.0M0.08%
62
FATEFate Therapeutics Inc
36,564$812.0M0.08%
63
ITCIEURIntra-Cellular Therapies Inc
52,005$800.0M0.07%
64
PDSBPDS Biotechnology Corporation
142,635$104.0M0.01%