ORBIMED ADVISORS LLC Q4 2020 Filing
Filed February 16, 2021
Portfolio Value
$11.4B
Holdings
148
Report Date
Q4 2020
Filing Type
13F-HR
All Holdings (148 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | PRLDPRELUDE THERAPEUTICS INC | 15,594,877 | $1.1T | 9763.82% | |
| 2 | SWTXSPRINGWORKS THERAPEUTICS INC | 7,406,307 | $537.1B | 4699.89% | |
| 3 | PMVPPMV PHARMACEUTICALS INC | 7,330,423 | $450.9B | 3945.51% | |
| 4 | SPRYSILVERBACK THERAPEUTICS INC | 8,740,887 | $405.1B | 3544.38% | |
| 5 | ABCLABCELLERA BIOLOGICS INC | 8,400,768 | $338.0B | 2958.05% | |
| 6 | —TURNING POINT THERAPEUTICS I | 2,745,327 | $334.5B | 2927.17% | |
| 7 | —PREVAIL THERAPEUTICS INC | 13,822,463 | $318.9B | 2790.36% | |
| 8 | IOVAIOVANCE BIOTHERAPEUTICS INC | 6,645,100 | $308.3B | 2698.04% | |
| 9 | MRTXEURMIRATI THERAPEUTICS INC | 1,145,300 | $251.6B | 2201.20% | |
| 10 | BSXBOSTON SCIENTIFIC CORP | 6,523,000 | $234.5B | 2051.99% | |
| 11 | BMYBRISTOL-MYERS SQUIBB CO | 3,549,100 | $220.2B | 1926.41% | |
| 12 | HZNPHORIZON THERAPEUTICS PUB L | 3,008,755 | $220.1B | 1925.88% | |
| 13 | MRKMERCK & CO. INC | 2,659,300 | $217.5B | 1903.48% | |
| 14 | NTRANATERA INC | 2,110,700 | $210.1B | 1838.08% | |
| 15 | VRTXVERTEX PHARMACEUTICALS INC | 834,100 | $197.1B | 1724.98% | |
| 16 | PASGPASSAGE BIO INC | 6,962,899 | $178.0B | 1557.93% | |
| 17 | ARQTARCUTIS BIOTHERAPEUTICS INC | 6,073,850 | $170.9B | 1495.07% | |
| 18 | AFIBACUTUS MED INC | 5,477,958 | $157.8B | 1380.99% | |
| 19 | —KINNATE BIOPHARMA INC | 3,847,929 | $153.1B | 1339.43% | |
| 20 | UNHUNITEDHEALTH GROUP INC | 390,300 | $136.9B | 1197.67% | |
| 21 | PFEPFIZER INC | 3,616,600 | $133.1B | 1164.92% | |
| 22 | —GRAYBUG VISION INC | 4,475,847 | $129.9B | 1136.58% | |
| 23 | BIIBBIOGEN INC | 529,400 | $129.6B | 1134.31% | |
| 24 | NBIXNEUROCRINE BIOSCIENCES INC | 1,301,715 | $124.8B | 1091.78% | |
| 25 | CNCCENTENE CORP DEL | 1,993,700 | $119.7B | 1047.27% | |
| 26 | KROSKEROS THERAPEUTICS INC | 1,679,417 | $118.5B | 1036.63% | |
| 27 | RPTXREPARE THERAPEUTICS INC | 3,426,325 | $117.5B | 1028.37% | |
| 28 | HUMHUMANA INC | 286,100 | $117.4B | 1027.11% | |
| 29 | TBPHTHERAVANCE BIOPHARMA INC | 6,219,110 | $110.5B | 967.04% | |
| 30 | NSTGEURNANOSTRING TECHNOLOGIES INC | 1,626,900 | $108.8B | 952.11% | |
| 31 | DC4DEXCOM INC | 279,100 | $103.2B | 902.95% | |
| 32 | SRPTSAREPTA THERAPEUTICS INC | 589,049 | $100.4B | 878.78% | Call |
| 33 | ELVANTHEM INC | 310,500 | $99.7B | 872.40% | |
| 34 | ORICORIC PHARMACEUTICALS INC | 2,921,967 | $98.9B | 865.49% | |
| 35 | BNRBURNING ROCK BIOTECH LTD | 4,161,675 | $96.1B | 841.22% | |
| 36 | AGIOAGIOS PHARMACEUTICALS INC | 2,207,321 | $95.6B | 836.92% | |
| 37 | TORCEURADICET BIO INC | 6,708,507 | $94.3B | 824.77% | |
| 38 | EWEDWARDS LIFESCIENCES CORP | 1,025,800 | $93.6B | 818.90% | |
| 39 | ABBVABBVIE INC | 862,300 | $92.4B | 808.49% | |
| 40 | ISRGINTUITIVE SURGICAL INC | 112,800 | $92.3B | 807.51% | |
| 41 | ETNBGBP89BIO INC | 3,729,442 | $90.9B | 795.30% | |
| 42 | XTNTXTANT MED HLDGS INC | 72,803,072 | $87.1B | 761.99% | |
| 43 | SVASINOVAC BIOTECH LTD | 2,839,500 | $72.0B | 630.03% | |
| 44 | PGNYPROGYNY INC | 1,675,500 | $71.0B | 621.49% | |
| 45 | GHGUARDANT HEALTH INC | 538,200 | $69.4B | 606.95% | |
| 46 | CRSPCRISPR THERAPEUTICS AG | 451,800 | $69.2B | 605.31% | |
| 47 | ATRCATRICURE INC | 1,228,189 | $68.4B | 598.29% | |
| 48 | 1T7TRICIDA INC | 9,614,280 | $67.8B | 593.11% | |
| 49 | AUPHAURINIA PHARMACEUTICALS INC | 4,754,000 | $65.7B | 575.32% | |
| 50 | —LOGICBIO THERAPEUTICS INC | 8,466,783 | $64.6B | 565.29% | |
| 51 | DCPHEURDECIPHERA PHARMACEUTICALS IN | 1,125,700 | $64.2B | 562.16% | |
| 52 | MGTXMEIRAGTX HLDGS PLC | 4,102,925 | $62.1B | 543.56% | |
| 53 | —IMARA INC | 2,719,902 | $60.0B | 524.80% | |
| 54 | ADVMCHFADVERUM BIOTECHNOLOGIES INC | 5,501,144 | $59.6B | 521.80% | |
| 55 | EHTHEHEALTH INC | 844,046 | $59.6B | 521.51% | |
| 56 | CHNGUSDCHANGE HEALTHCARE INC | 3,093,700 | $57.7B | 504.88% | |
| 57 | SYKSTRYKER CORPORATION | 235,000 | $57.6B | 503.88% | |
| 58 | ASNDASCENDIS PHARMA A/S | 336,500 | $56.1B | 491.08% | |
| 59 | ARCTARCTURUS THERAPEUTICS HLDGS | 1,280,086 | $55.5B | 485.91% | |
| 60 | ACHCACADIA HEALTHCARE COMPANY IN | 1,035,160 | $52.0B | 455.26% | |
| 61 | TMOTHERMO FISHER SCIENTIFIC INC | 110,300 | $51.4B | 449.56% | |
| 62 | GLTOUSDGALECTO INC | 4,090,937 | $51.2B | 447.83% | |
| 63 | MREOMEREO BIOPHARMA GROUP PLC | 13,816,488 | $49.5B | 432.82% | |
| 64 | TELATELA BIO INC | 3,027,542 | $45.5B | 398.44% | |
| 65 | TREURTRILLIUM THERAPEUTICS INC | 2,960,200 | $43.5B | 381.04% | |
| 66 | SIBNSI BONE INC | 1,368,500 | $40.9B | 358.05% | |
| 67 | ATNXEURATHENEX INC | 3,694,061 | $40.9B | 357.51% | |
| 68 | VRNAVERONA PHARMA PLC | 5,694,841 | $39.9B | 348.83% | |
| 69 | APLTAPPLIED THERAPEUTICS INC | 1,771,831 | $39.0B | 341.25% | |
| 70 | CRNXCRINETICS PHARMACEUTICALS IN | 2,753,567 | $38.9B | 339.98% | |
| 71 | NVLSEURALPINE IMMUNE SCIENCES INC | 3,070,955 | $38.7B | 338.59% | |
| 72 | XENEXENON PHARMACEUTICALS INC | 2,497,917 | $38.4B | 336.17% | |
| 73 | —FUSION PHARMACEUTICALS INC | 3,224,770 | $37.9B | 331.56% | |
| 74 | KALAKALA PHARMACEUTICALS INC | 5,465,030 | $37.1B | 324.23% | |
| 75 | —CURIS INC | 4,366,494 | $35.8B | 312.93% | |
| 76 | —APTOSE BIOSCIENCES INC | 8,030,000 | $35.2B | 307.76% | |
| 77 | QUREUNIQURE NV | 969,079 | $35.0B | 306.38% | |
| 78 | MOHMOLINA HEALTHCARE INC | 162,400 | $34.5B | 302.23% | |
| 79 | ALECALECTOR INC | 2,225,313 | $33.6B | 294.03% | |
| 80 | AGLEUSDAEGLEA BIOTHERAPEUTICS INC | 4,015,524 | $31.6B | 276.53% | |
| 81 | OLMAOLEMA PHARMACEUTICALS INC | 650,992 | $31.3B | 273.89% | |
| 82 | CTIC1USDCTI BIOPHARMA CORP | 9,520,600 | $30.7B | 268.25% | |
| 83 | —HARPOON THERAPEUTICS INC | 1,835,704 | $30.5B | 266.81% | |
| 84 | NXTCNEXTCURE INC | 2,711,013 | $29.6B | 258.57% | |
| 85 | NBPI MAB | 606,070 | $28.6B | 250.05% | |
| 86 | OSH3EUROAK STR HEALTH INC | 448,100 | $27.4B | 239.81% | |
| 87 | —FLEXION THERAPEUTICS INC | 2,308,083 | $26.6B | 233.07% | |
| 88 | ALXNALEXION PHARMACEUTICALS INC | 169,000 | $26.4B | 231.05% | |
| 89 | SNDXSYNDAX PHARMACEUTICALS INC | 1,170,900 | $26.0B | 227.87% | |
| 90 | SCPHSCPHARMACEUTICALS INC | 4,797,148 | $25.4B | 222.06% | |
| 91 | HRTXHERON THERAPEUTICS INC | 1,191,846 | $25.2B | 220.73% | |
| 92 | CRVSCORVUS PHARMACEUTICALS INC | 6,767,584 | $24.1B | 210.82% | |
| 93 | —SIERRA ONCOLOGY INC | 1,477,320 | $23.7B | 207.22% | |
| 94 | ALCALCON AG | 351,380 | $23.4B | 204.38% | |
| 95 | FLBFLUIDIGM CORP DEL | 3,892,346 | $23.4B | 204.36% | |
| 96 | —9 METERS BIOPHARMA INC | 25,716,755 | $22.1B | 193.31% | |
| 97 | —PANDION THERAPEUTICS INC | 1,480,940 | $22.0B | 192.44% | |
| 98 | PRTAPROTHENA CORP PLC | 1,797,458 | $21.6B | 188.90% | |
| 99 | AMGNAMGEN INC | 91,500 | $21.0B | 184.09% | |
| 100 | OTICEUROTONOMY INC | 3,250,000 | $21.0B | 184.00% |
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