ORBIMED ADVISORS LLC Q4 2016 Filing
Filed February 14, 2017
Portfolio Value
$7.8B
Holdings
129
Report Date
Q4 2016
Filing Type
13F-HR
All Holdings (129 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | ALXNALEXION PHARMACEUTICALS INC | 3,488,386 | $426.8B | 5438.36% | Call |
| 2 | BIIBBIOGEN INC | 1,281,200 | $363.3B | 4629.48% | |
| 3 | CELGCELGENE CORP | 3,106,777 | $359.6B | 4582.16% | |
| 4 | BSXBOSTON SCIENTIFIC CORP | 16,506,900 | $357.0B | 4549.48% | |
| 5 | AMGNAMGEN INC | 2,331,800 | $340.9B | 4344.18% | |
| 6 | MRKMERCK & CO INC | 4,615,200 | $271.7B | 3461.98% | |
| 7 | LLYLILLY ELI & CO | 2,889,000 | $212.5B | 2707.51% | Call |
| 8 | INCYINCYTE CORP | 2,082,800 | $208.8B | 2661.08% | |
| 9 | —SHIRE PLC | 1,203,351 | $205.0B | 2612.47% | |
| 10 | HUMHUMANA INC | 936,400 | $191.1B | 2434.42% | Call |
| 11 | ABBVABBVIE INC | 2,925,000 | $183.2B | 2333.89% | |
| 12 | —WRIGHT MED GROUP N V | 7,584,334 | $174.3B | 2220.79% | |
| 13 | PFEPFIZER INC | 5,167,900 | $167.9B | 2138.79% | |
| 14 | AG8AGILENT TECHNOLOGIES INC | 3,629,900 | $165.4B | 2107.26% | |
| 15 | —ALLERGAN PLC | 769,690 | $161.6B | 2059.67% | |
| 16 | VRTXVERTEX PHARMACEUTICALS INC | 2,159,400 | $159.1B | 2027.05% | |
| 17 | HCAHCA HOLDINGS INC | 2,002,200 | $148.2B | 1888.41% | |
| 18 | ELVANTHEM INC | 1,021,600 | $146.9B | 1871.49% | |
| 19 | ARRYEURARRAY BIOPHARMA INC | 16,088,800 | $141.4B | 1802.00% | |
| 20 | REGNREGENERON PHARMACEUTICALS | 355,300 | $130.4B | 1661.91% | |
| 21 | EWEDWARDS LIFESCIENCES CORP | 1,351,400 | $126.6B | 1613.48% | |
| 22 | ICPTUSDINTERCEPT PHARMACEUTICALS IN | 1,120,000 | $121.7B | 1550.56% | |
| 23 | TMOTHERMO FISHER SCIENTIFIC INC | 799,500 | $112.8B | 1437.42% | |
| 24 | —SYNERGY PHARMACEUTICALS DEL | 18,241,398 | $111.1B | 1415.52% | |
| 25 | IRWDIRONWOOD PHARMACEUTICALS INC | 7,241,300 | $110.7B | 1410.79% | |
| 26 | BMRNBIOMARIN PHARMACEUTICAL INC | 1,274,100 | $105.5B | 1344.87% | |
| 27 | —AETNA INC NEW | 805,900 | $99.9B | 1273.44% | |
| 28 | JNJJOHNSON & JOHNSON | 858,000 | $98.8B | 1259.55% | |
| 29 | ISRGINTUITIVE SURGICAL INC | 145,500 | $92.3B | 1175.74% | |
| 30 | —AUDENTES THERAPEUTICS INC | 4,801,638 | $87.7B | 1117.81% | |
| 31 | BMYBRISTOL MYERS SQUIBB CO | 1,493,500 | $87.3B | 1112.13% | |
| 32 | NBIXNEUROCRINE BIOSCIENCES INC | 2,128,774 | $82.4B | 1049.74% | |
| 33 | CRVSCORVUS PHARMACEUTICALS INC | 5,379,349 | $76.9B | 980.18% | |
| 34 | GILDGILEAD SCIENCES INC | 1,055,100 | $75.6B | 962.74% | |
| 35 | GKOSGLAUKOS CORP | 2,180,000 | $74.8B | 952.78% | |
| 36 | —MALLINCKRODT PUB LTD CO | 1,472,700 | $73.4B | 934.89% | |
| 37 | IM8NINSMED INC | 5,301,805 | $70.1B | 893.77% | |
| 38 | PBYIPUMA BIOTECHNOLOGY INC | 2,275,825 | $69.9B | 890.26% | |
| 39 | —ALLERGAN PLC | 88,200 | $67.2B | 856.89% | |
| 40 | —MAGELLAN HEALTH INC | 801,600 | $60.3B | 768.60% | |
| 41 | AERIEURAERIE PHARMACEUTICALS INC | 1,496,000 | $56.6B | 721.51% | |
| 42 | INSYEURINSYS THERAPEUTICS INC NEW | 6,071,440 | $55.9B | 711.73% | |
| 43 | —LOXO ONCOLOGY INC | 1,728,000 | $55.5B | 707.12% | |
| 44 | THCTENET HEALTHCARE CORP | 3,716,700 | $55.2B | 702.80% | |
| 45 | ASNDASCENDIS PHARMA A S | 2,717,315 | $55.0B | 700.79% | |
| 46 | MDTMEDTRONIC PLC | 766,600 | $54.6B | 695.78% | |
| 47 | —ACHILLION PHARMACEUTICALS IN | 13,107,200 | $54.1B | 689.77% | |
| 48 | EGRXEAGLE PHARMACEUTICALS INC | 671,000 | $53.2B | 678.35% | |
| 49 | UNHUNITEDHEALTH GROUP INC | 296,400 | $47.4B | 604.43% | |
| 50 | —MOMENTA PHARMACEUTICALS INC | 2,951,968 | $44.4B | 566.09% | |
| 51 | —GW PHARMACEUTICALS PLC | 396,600 | $44.3B | 564.73% | |
| 52 | COOCOOPER COS INC | 250,100 | $43.8B | 557.47% | |
| 53 | JAZZJAZZ PHARMACEUTICALS PLC | 371,400 | $40.5B | 515.98% | |
| 54 | SYKSTRYKER CORP | 316,300 | $37.9B | 482.87% | |
| 55 | NTLAINTELLIA THERAPEUTICS INC | 2,662,180 | $34.9B | 444.71% | |
| 56 | SELBUSDSELECTA BIOSCIENCES INC | 1,842,797 | $31.6B | 402.70% | |
| 57 | —IMMUNOMEDICS INC | 30,000,000 | $29.8B | 379.32% | |
| 58 | OTICEUROTONOMY INC | 1,850,094 | $29.4B | 374.82% | |
| 59 | VRAYQVIEWRAY INC | 9,127,990 | $28.6B | 364.05% | |
| 60 | ONCBEIGENE LTD | 903,700 | $27.4B | 349.59% | |
| 61 | MOHMOLINA HEALTHCARE INC | 496,200 | $26.9B | 343.07% | |
| 62 | CHRSCOHERUS BIOSCIENCES INC | 850,100 | $23.9B | 304.92% | |
| 63 | —LION BIOTECHNOLOGIES INC | 3,382,900 | $23.5B | 299.58% | |
| 64 | —DIMENSION THERAPEUTICS INC | 5,397,698 | $23.5B | 299.18% | |
| 65 | ILMNILLUMINA INC | 182,200 | $23.3B | 297.26% | |
| 66 | TEVATEVA PHARMACEUTICAL INDS LTD | 614,500 | $22.3B | 283.84% | |
| 67 | XNCRXENCOR INC | 840,237 | $22.1B | 281.79% | |
| 68 | —NEWLINK GENETICS CORP | 1,991,700 | $20.5B | 260.89% | |
| 69 | EHTHEHEALTH INC | 1,820,000 | $19.4B | 246.98% | |
| 70 | GLPGGALAPAGOS NV | 283,500 | $18.2B | 231.88% | |
| 71 | —BLUEBIRD BIO INC | 283,800 | $17.5B | 223.11% | |
| 72 | ASMBASSEMBLY BIOSCIENCES INC | 1,397,100 | $17.0B | 216.30% | |
| 73 | SVASINOVAC BIOTECH LTD | 2,667,500 | $15.7B | 200.53% | |
| 74 | NTRANATERA INC | 1,276,190 | $14.9B | 190.42% | |
| 75 | —IMMUNOMEDICS INC | 3,802,000 | $14.0B | 177.79% | |
| 76 | BCRUSDBARD C R INC | 58,000 | $13.0B | 166.03% | |
| 77 | —DERMIRA INC | 425,600 | $12.9B | 164.47% | |
| 78 | FLBFLUIDIGM CORP DEL | 1,746,100 | $12.7B | 161.98% | |
| 79 | EXASEXACT SCIENCES CORP | 950,000 | $12.7B | 161.72% | |
| 80 | IMGNEURIMMUNOGEN INC | 6,095,647 | $12.4B | 158.45% | |
| 81 | —PORTOLA PHARMACEUTICALS INC | 551,500 | $12.4B | 157.70% | |
| 82 | —DBV TECHNOLOGIES S A | 345,700 | $12.1B | 154.74% | |
| 83 | —FORWARD PHARMA A/S | 798,000 | $12.0B | 152.52% | |
| 84 | VNDAVANDA PHARMACEUTICALS INC | 750,000 | $12.0B | 152.43% | Call |
| 85 | RAREULTRAGENYX PHARMACEUTICAL IN | 169,300 | $11.9B | 151.67% | |
| 86 | PRQRPROQR THRAPEUTICS N V | 2,305,446 | $11.3B | 143.95% | |
| 87 | —INOTEK PHARMACEUTICALS CORP | 1,849,300 | $11.3B | 143.74% | |
| 88 | SEMSELECT MED HLDGS CORP | 831,900 | $11.0B | 140.46% | |
| 89 | PIRSPIERIS PHARMACEUTICALS INC | 7,259,620 | $10.2B | 129.98% | |
| 90 | —NABRIVA THERAPEUTICS AG | 1,677,940 | $10.0B | 127.43% | |
| 91 | ABTABBOTT LABS | 245,400 | $9.4B | 120.11% | |
| 92 | —INCYTE CORP | 4,250,000 | $8.7B | 110.47% | |
| 93 | —INCYTE CORP | 4,250,000 | $8.5B | 108.26% | |
| 94 | NUVAGBPNUVASIVE INC | 123,500 | $8.3B | 106.00% | |
| 95 | —STEADYMED LTD | 3,072,196 | $8.0B | 101.78% | |
| 96 | XENEXENON PHARMACEUTICALS INC | 1,000,000 | $7.7B | 98.11% | |
| 97 | CRSPCRISPR THERAPEUTICS AG | 372,191 | $7.5B | 96.09% | |
| 98 | —INOTEK PHARMACEUTICALS CORP | 7,000,000 | $7.4B | 93.71% | |
| 99 | LAB 2.75 02/01/34FLUIDIGM CORP DEL | 10,000,000 | $7.0B | 89.36% | |
| 100 | NERVGBPMINERVA NEUROSCIENCES INC | 556,200 | $6.5B | 83.27% |
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