ORBIMED ADVISORS LLC Q2 2021 Filing
Filed August 16, 2021
Portfolio Value
$9.9B
Holdings
157
Report Date
Q2 2021
Filing Type
13F-HR
All Holdings (157 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | SWTXSPRINGWORKS THERAPEUTICS INC | 6,044,266 | $498.1B | 5038.13% | |
| 2 | BSXBOSTON SCIENTIFIC CORP | 7,170,600 | $306.6B | 3101.27% | Call |
| 3 | BMYBRISTOL-MYERS SQUIBB CO | 4,515,400 | $301.7B | 3051.75% | |
| 4 | EWTXEDGEWISE THERAPEUTICS INC | 13,944,680 | $297.4B | 3008.47% | |
| 5 | MRKMERCK & CO INC | 3,732,400 | $290.3B | 2935.93% | |
| 6 | PRLDPRELUDE THERAPEUTICS INC | 10,039,691 | $287.4B | 2907.28% | |
| 7 | HZNPHORIZON THERAPEUTICS PUB L | 2,922,155 | $273.6B | 2767.65% | |
| 8 | SPRYSILVERBACK THERAPEUTICS INC | 8,740,887 | $270.0B | 2730.98% | |
| 9 | PMVPPMV PHARMACEUTICALS INC | 7,330,423 | $250.4B | 2532.75% | |
| 10 | NTRANATERA INC | 2,057,800 | $233.6B | 2362.98% | |
| 11 | VRTXVERTEX PHARMACEUTICALS INC | 1,065,400 | $214.8B | 2172.77% | |
| 12 | MRTXEURMIRATI THERAPEUTICS INC | 1,264,200 | $204.2B | 2065.45% | |
| 13 | —TURNING POINT THERAPEUTICS I | 2,361,327 | $184.2B | 1863.41% | |
| 14 | IOVAIOVANCE BIOTHERAPEUTICS INC | 6,645,100 | $172.9B | 1748.86% | |
| 15 | ARQTARCUTIS BIOTHERAPEUTICS INC | 6,073,850 | $165.8B | 1676.53% | |
| 16 | IMAPRELUDE THERAPEUTICS INC | 5,680,186 | $162.6B | 1644.87% | |
| 17 | UNHUNITEDHEALTH GROUP INC | 389,700 | $156.1B | 1578.38% | |
| 18 | GHGUARDANT HEALTH INC | 1,227,400 | $152.4B | 1541.77% | |
| 19 | HUMHUMANA INC | 335,000 | $148.3B | 1500.10% | |
| 20 | ABCLABCELLERA BIOLOGICS INC | 6,223,019 | $136.9B | 1384.74% | |
| 21 | ABBVABBVIE INC | 1,167,500 | $131.5B | 1330.13% | |
| 22 | ISRGINTUITIVE SURGICAL INC | 139,600 | $128.4B | 1298.52% | |
| 23 | ELVANTHEM INC | 335,700 | $128.2B | 1296.38% | |
| 24 | DC4DEXCOM INC | 297,400 | $127.0B | 1284.44% | |
| 25 | XBISPDR SER TR | 935,700 | $126.7B | 1281.45% | |
| 26 | DCPHEURDECIPHERA PHARMACEUTICALS IN | 3,297,301 | $120.7B | 1220.97% | |
| 27 | NBIXNEUROCRINE BIOSCIENCES INC | 1,231,115 | $119.8B | 1211.84% | |
| 28 | XTNTXTANT MED HLDGS INC | 72,873,494 | $118.8B | 1201.44% | |
| 29 | EWEDWARDS LIFESCIENCES CORP | 1,126,400 | $116.7B | 1179.97% | |
| 30 | RPTXREPARE THERAPEUTICS INC | 3,426,325 | $106.8B | 1080.57% | |
| 31 | GRCLGRACELL BIOTECHNOLOGIES INC | 7,884,870 | $102.5B | 1036.77% | |
| 32 | NPCENEUROPACE INC | 4,012,281 | $95.5B | 965.45% | |
| 33 | AFIBACUTUS MED INC | 5,477,958 | $93.0B | 940.81% | |
| 34 | PASGPASSAGE BIO INC | 6,962,899 | $92.2B | 932.45% | |
| 35 | —KINNATE BIOPHARMA INC | 3,847,929 | $89.6B | 906.06% | |
| 36 | SYKSTRYKER CORPORATION | 337,400 | $87.6B | 886.37% | |
| 37 | IMAIKENA ONCOLOGY INC | 6,215,466 | $87.3B | 882.64% | |
| 38 | JANXJANUX THERAPEUTICS INC | 3,466,386 | $86.5B | 874.77% | |
| 39 | IMGNEURIMMUNOGEN INC | 12,936,622 | $85.3B | 862.28% | |
| 40 | CRSPCRISPR THERAPEUTICS AG | 519,000 | $84.0B | 849.83% | |
| 41 | PGNYPROGYNY INC | 1,365,445 | $80.6B | 814.84% | |
| 42 | AUPHAURINIA PHARMACEUTICALS INC | 6,069,032 | $78.7B | 795.56% | |
| 43 | OSH3EUROAK STR HEALTH INC | 1,328,300 | $77.8B | 786.90% | |
| 44 | SVASINOVAC BIOTECH LTD | 2,839,500 | $76.8B | 776.80% | |
| 45 | TORCEURADICET BIO INC | 7,232,856 | $74.4B | 752.78% | |
| 46 | KROSKEROS THERAPEUTICS INC | 1,679,417 | $71.3B | 721.42% | |
| 47 | ETNBGBP89BIO INC | 3,729,442 | $69.7B | 705.40% | |
| 48 | TBPHTHERAVANCE BIOPHARMA INC | 4,564,045 | $66.3B | 670.29% | |
| 49 | MGTXMEIRAGTX HLDGS PLC | 4,102,925 | $63.6B | 643.23% | |
| 50 | —VECTIVBIO HLDG AG | 5,123,304 | $59.7B | 604.22% | |
| 51 | ASNDASCENDIS PHARMA A/S | 447,859 | $58.9B | 595.91% | |
| 52 | CRNXCRINETICS PHARMACEUTICALS IN | 2,996,876 | $56.5B | 571.38% | |
| 53 | TMOTHERMO FISHER SCIENTIFIC INC | 110,300 | $55.6B | 562.80% | |
| 54 | —SINGULAR GENOMICS SYSTEMS IN | 1,998,521 | $54.9B | 555.48% | |
| 55 | MREOMEREO BIOPHARMA GROUP PLC | 17,264,764 | $54.7B | 553.57% | |
| 56 | BNRBURNING ROCK BIOTECH LTD | 1,856,201 | $54.7B | 553.10% | |
| 57 | SEMSELECT MED HLDGS CORP | 1,271,100 | $53.7B | 543.32% | |
| 58 | CMMBCHEMOMAB THERAPEUTICS LTD | 2,578,174 | $49.0B | 495.99% | |
| 59 | TELATELA BIO INC | 3,027,542 | $48.8B | 493.33% | |
| 60 | APLTAPPLIED THERAPEUTICS INC | 2,257,387 | $46.9B | 474.46% | |
| 61 | TERNTERNS PHARMACEUTICALS INC | 3,791,204 | $46.5B | 470.12% | |
| 62 | VTGNUSDVISTAGEN THERAPEUTICS INC | 14,467,872 | $45.6B | 460.96% | |
| 63 | —DECIBEL THERAPEUTICS INC | 4,945,192 | $42.5B | 430.16% | |
| 64 | NVV1NOVAVAX INC | 200,295 | $42.5B | 430.12% | |
| 65 | 1T7TRICIDA INC | 9,614,280 | $41.5B | 420.10% | |
| 66 | ORICORIC PHARMACEUTICALS INC | 2,337,574 | $41.4B | 418.26% | |
| 67 | —IKENA ONCOLOGY INC | 2,933,941 | $41.2B | 416.65% | |
| 68 | SIBNSI-BONE INC | 1,305,300 | $41.1B | 415.48% | |
| 69 | —MERSANA THERAPEUTICS INC | 2,800,247 | $38.0B | 384.63% | |
| 70 | —GEMINI THERAPEUTICS INC | 5,826,224 | $37.7B | 381.28% | |
| 71 | —LOGICBIO THERAPEUTICS INC | 8,466,783 | $37.6B | 380.24% | |
| 72 | VRNAVERONA PHARMA PLC | 5,694,841 | $37.2B | 376.71% | |
| 73 | —HARPOON THERAPEUTICS INC | 2,611,308 | $36.2B | 366.34% | |
| 74 | NSTGEURNANOSTRING TECHNOLOGIES INC | 556,000 | $36.0B | 364.36% | |
| 75 | GRPHGRAPHITE BIO INC | 1,106,307 | $34.0B | 343.86% | |
| 76 | TREURTRILLIUM THERAPEUTICS INC | 3,322,300 | $32.2B | 325.95% | |
| 77 | GHRSGH RESEARCH PLC | 1,428,666 | $31.0B | 314.01% | |
| 78 | CGEMCULLINAN ONCOLOGY INC | 1,146,145 | $29.5B | 298.51% | |
| 79 | SCPHSCPHARMACEUTICALS INC | 4,797,148 | $29.3B | 296.47% | |
| 80 | KALAKALA PHARMACEUTICALS INC | 5,465,030 | $29.0B | 292.97% | |
| 81 | —SIERRA ONCOLOGY INC | 1,477,320 | $28.8B | 290.92% | |
| 82 | FLBFLUIDIGM CORP DEL | 4,661,871 | $28.7B | 290.46% | |
| 83 | ARCTARCTURUS THERAPEUTICS HLDGS | 848,503 | $28.7B | 290.42% | |
| 84 | —CURIS INC | 3,521,400 | $28.4B | 287.43% | |
| 85 | AGLEUSDAEGLEA BIOTHERAPEUTICS INC | 4,015,524 | $27.9B | 282.68% | |
| 86 | ALXNALEXION PHARMACEUTICALS INC | 150,900 | $27.7B | 280.39% | |
| 87 | NVLSEURALPINE IMMUNE SCIENCES INC | 3,070,955 | $27.6B | 279.56% | |
| 88 | —APTOSE BIOSCIENCES INC | 8,030,000 | $26.7B | 269.65% | |
| 89 | —FUSION PHARMACEUTICALS INC | 3,224,770 | $26.1B | 263.54% | |
| 90 | XENEXENON PHARMACEUTICALS INC | 1,334,217 | $24.8B | 251.28% | |
| 91 | BIIBBIOGEN INC | 67,400 | $23.3B | 236.06% | |
| 92 | —FLEXION THERAPEUTICS INC | 2,769,383 | $22.8B | 230.53% | |
| 93 | —GRAYBUG VISION INC | 4,163,347 | $22.6B | 228.66% | |
| 94 | OLMAOLEMA PHARMACEUTICALS INC | 807,792 | $22.6B | 228.61% | |
| 95 | NXTCNEXTCURE INC | 2,711,013 | $21.8B | 220.18% | |
| 96 | CRVSCORVUS PHARMACEUTICALS INC | 8,053,298 | $21.5B | 217.48% | |
| 97 | —IMARA INC | 2,719,902 | $21.5B | 217.33% | |
| 98 | PCVXVAXCYTE INC | 945,400 | $21.3B | 215.25% | |
| 99 | GLTOUSDGALECTO INC | 4,090,937 | $20.7B | 209.37% | |
| 100 | —MAGENTA THERAPEUTICS INC | 2,033,759 | $19.9B | 201.18% |
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