Darwin Global Management, Ltd.

CIK: 0001839209SEC EDGAR →

Portfolio Value

$4.9B

Holdings

6

As of

Q4 2025

New Positions

3

Closed Positions

3

Portfolio Value History

Top 10 Holdings

RankStockSharesValue% of Portfolio
1
IM8N

INSMED INC

20,933,277$3.6B
73.78%
2
BLTE

BELITE BIO INC

3,027,704$486.9M
9.86%
3
ABVX

ABIVAX SA

3,178,501$439.7M
8.90%
4
CDTX

CIDARA THERAPEUTICS INC

997,196$220.2M
4.46%
5
WVE

WAVE LIFE SCIENCES LTD

7,298,421$125.2M
2.53%
6
CAPR

CAPRICOR THERAPEUTICS INC

800,000$23.2M
0.47%

Quarterly Changes

Top Buys

IM8N↑ Increased
$746.5M
BLTENEW
$486.9M
ABVX↑ Increased
$176.0M
WVENEW
$125.2M
CAPRNEW
$23.2M

Top Sells

UTHCLOSED
$317.6M
QURECLOSED
$23.8M

New Positions (3)

BLTE
$486.9M · 3.0M shares
WVE
$125.2M · 7.3M shares
CAPR
$23.2M · 800K shares

Closed Positions (2)

UTH
$317.6M · 749K shares
QURE
$23.8M · 400K shares

Sector Breakdown

Sector# HoldingsValue%
Unknown2$3.9B78.2%
Healthcare4$1.1B21.8%