Who Owns Protalix BioTherapeutics, Inc. (PLX)?Hedge Fund & Institutional Holders
Institutional Holders
50
as of Q4 2025
Total Institutional Value
$4.4604000200009994e+86T
% of Float Held
3.6835777428120947e+250%
QoQ Change in Holders
+15 / -2
Price History
PLX — Biggest New Institutional Buyers This Quarter
| Fund | Action | Shares Added | Value Added |
|---|---|---|---|
| EVERGREEN CAPITAL MANAGEMENT LLC | New Position | +171K | +$308K |
| Round Rock Advisors LLC | New Position | +155K | +$279K |
| Orin Green Financial, LLC | New Position | +61K | +$110K |
| EARNED WEALTH ADVISORS, LLC | New Position | +26K | +$46K |
| State of Alaska, Department of Revenue | New Position | +22K | +$39K |
| SG Americas Securities, LLC | New Position | +17K | +$31K |
| R Squared Ltd | New Position | +15K | +$26K |
| Cascade Financial Partners, LLC | New Position | +12K | +$21K |
| TD Waterhouse Canada Inc. | New Position | +6K | +$10K |
| Investment Research & Advisory Group, Inc. | New Position | +1K | +$1K |
| LAZARD ASSET MANAGEMENT LLC | New Position | +71K | +$0 |
| MARSHALL WACE, LLP | New Position | +19K | +$0 |
| Equitable Holdings, Inc. | New Position | +11K | +$0 |
| Bank of New York Mellon Corp | New Position | +211K | +$0 |
| TWO SIGMA SECURITIES, LLC | New Position | +40K | +$0 |
PLX — Institutions Reducing or Closing Positions
| Fund | Action | Shares Sold | Value Sold |
|---|---|---|---|
| Opaleye Management Inc. | Decreased | -102K | -$5.7B |
| RENAISSANCE TECHNOLOGIES LLC | Decreased | -52K | -$2.9B |
| NORTHERN TRUST CORP | Decreased | -37K | -$2.0B |
| Connor, Clark & Lunn Investment Management Ltd. | Decreased | -168K | -$888.9M |
| Diametric Capital, LP | Decreased | -41K | -$399.3M |
| XTX Topco Ltd | Decreased | -52K | -$190.6M |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Decreased | -34K | -$161.9M |
| WOLVERINE TRADING, LLC | Closed Position | -70K | -$152.1M |
| DEUTSCHE BANK AG\ | Decreased | -65K | -$145.7M |
| RHUMBLINE ADVISERS | Decreased | -21K | -$144.7M |
| PRELUDE CAPITAL MANAGEMENT, LLC | Decreased | -28K | -$110.5M |
| Finivi Inc. | Closed Position | -73K | -$88.2M |
| INTECH INVESTMENT MANAGEMENT LLC | Decreased | -115 | -$69.4M |
| MANUFACTURERS LIFE INSURANCE COMPANY, THE | Decreased | -6K | -$53.4M |
| Kestra Advisory Services, LLC | Decreased | -1K | -$24.4M |
Top Institutional Holders(Q4 2025)
PLX Institutional Ownership History
| Quarter | Holders | Total Value | Change |
|---|---|---|---|
| Q4 2025 | 83 | $17.3M | +19 |
| Q3 2025 | 64 | $29.4B | +9 |
| Q2 2025 | 55 | $13.6B | -8 |
| Q1 2025 | 63 | $20.2B | +17 |
| Q4 2024 | 46 | $554.0B | +6 |
| Q3 2024 | 40 | $1.1T | -18 |
| Q2 2024 | 58 | $2.6T | +2 |
| Q1 2024 | 56 | $4.7T | — |
Similar Stocks by Institutional Ownership
As of Q4 2025, 50 institutional investors hold PLX (Protalix BioTherapeutics, Inc.). The largest holder is Opaleye Management Inc. with $4.5M in shares. This quarter, 15 institutions opened new positions and 2 closed their positions.
Frequently Asked Questions
How many hedge funds own PLX?
As of Q4 2025, 50 institutional investors report holding PLX (Protalix BioTherapeutics, Inc.) in their 13F filings.
Who is the largest institutional holder of PLX?
The largest institutional holder of PLX is Opaleye Management Inc. with $4.5M in shares.
Is institutional ownership of PLX increasing or decreasing?
This quarter, 15 institutions opened new positions in PLX and 2 closed their positions.