Who Owns Ionis Pharmaceuticals, Inc. (IONS)?Hedge Fund & Institutional Holders

$72.43+1.24 (+1.74%)HealthcareNASDAQ

Institutional Holders

7

as of Q4 2025

Total Institutional Value

$6.00000049990004e+38T

% of Float Held

5.1062608464347714e+26%

QoQ Change in Holders

+0 / -0

Price History

$25.51$40.76$56.00$71.25$86.50Sep 24Jun 25Mar 26

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1SIMPLEX TRADING, LLC82,600$6.0B3.38%Put
2GROUP ONE TRADING LLC63,200$5.0B8.73%Call
3SIMPLEX TRADING, LLC56,600$4.0B2.25%Call
4GROUP ONE TRADING LLC32,300$2.6B4.46%Put
5IMC-Chicago, LLC23,600$1.9B0.68%Call
6IMC-Chicago, LLC14,900$1.2B0.43%Put
7Persistent Asset Partners Ltd285$432.0M0.19%Call

Similar Stocks by Institutional Ownership

As of Q4 2025, 7 institutional investors hold IONS (Ionis Pharmaceuticals, Inc.). The largest holder is SIMPLEX TRADING, LLC with $6.0B in shares. This quarter, 0 institutions opened new positions and 0 closed their positions.

Frequently Asked Questions

How many hedge funds own IONS?

As of Q4 2025, 7 institutional investors report holding IONS (Ionis Pharmaceuticals, Inc.) in their 13F filings.

Who is the largest institutional holder of IONS?

The largest institutional holder of IONS is SIMPLEX TRADING, LLC with $6.0B in shares.

Is institutional ownership of IONS increasing or decreasing?

This quarter, 0 institutions opened new positions in IONS and 0 closed their positions.