Who Owns Ensysce Biosciences, Inc. (ENSC)?Hedge Fund & Institutional Holders
Institutional Holders
19
as of Q4 2025
Total Institutional Value
$7900016000222000128.0T
% of Float Held
3.6886916209081906e+72%
QoQ Change in Holders
+6 / -5
Price History
ENSC — Biggest New Institutional Buyers This Quarter
| Fund | Action | Shares Added | Value Added |
|---|---|---|---|
| Williams & Novak, LLC | New Position | +18K | +$16.0M |
| Financial Plan, Inc. | New Position | +24K | +$22K |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | +9K | +$0 |
| TWO SIGMA SECURITIES, LLC | New Position | +22K | +$0 |
| HRT FINANCIAL LP | New Position | +24K | +$0 |
| SBI Securities Co., Ltd. | New Position | +421 | +$0 |
| BANK OF AMERICA CORP /DE/ | Increased | +48 | +$0 |
| JONES FINANCIAL COMPANIES LLLP | New Position | +41 | +$0 |
| Tower Research Capital LLC (TRC) | Increased | +4K | +$-3.2M |
| DRW Securities, LLC | Increased | +29K | +$-163.9M |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Increased | +75K | +$-177.1M |
ENSC — Institutions Reducing or Closing Positions
| Fund | Action | Shares Sold | Value Sold |
|---|---|---|---|
| RENAISSANCE TECHNOLOGIES LLC | Closed Position | -16K | -$36.9M |
| CITADEL ADVISORS LLC | Closed Position | -15K | -$34.4M |
| XTX Topco Ltd | Closed Position | -11K | -$26.0M |
| UBS Group AG | Decreased | -700 | -$1.9M |
| Virtu Financial LLC | Closed Position | -14K | -$34K |
| ASSETMARK, INC | Closed Position | -13 | -$31K |
Top Institutional Holders(Q4 2025)
| # | Fund | Shares | Value | % of Portfolio | Type |
|---|---|---|---|---|---|
| 1 | PERCEPTIVE ADVISORS LLC | 86,666 | $79.0M | 1.41% | Share |
| 2 | Williams & Novak, LLC | 17,850 | $16.0M | 0.01% | Share |
| 3 | Financial Plan, Inc. | 24,000 | $22K | 0.00% | Share |
| 4 | FNY Investment Advisers, LLC | 3,000 | $2K | 0.00% | Share |
| 5 | VANGUARD GROUP INC | 23,854 | $0 | 0.00% | Share |
| 6 | GEODE CAPITAL MANAGEMENT, LLC | 20,929 | $0 | 0.00% | Share |
| 7 | GEODE CAPITAL MANAGEMENT, LLC | 1,161 | $0 | 0.00% | Share |
| 8 | BlackRock, Inc. | 65 | $0 | 0.00% | Share |
| 9 | DRW Securities, LLC | 98,481 | $0 | 0.00% | Share |
| 10 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 149,711 | $0 | 0.00% | Share |
| 11 | UBS Group AG | 100 | $0 | 0.00% | Share |
| 12 | Tower Research Capital LLC (TRC) | 5,319 | $0 | 0.00% | Share |
| 13 | BANK OF AMERICA CORP /DE/ | 24 | $0 | 0.00% | Share |
| 14 | BANK OF AMERICA CORP /DE/ | 48 | $0 | 0.00% | Share |
| 15 | JONES FINANCIAL COMPANIES LLLP | 41 | $0 | 0.00% | Share |
| 16 | SBI Securities Co., Ltd. | 421 | $0 | 0.00% | Share |
| 17 | HRT FINANCIAL LP | 24,491 | $0 | 0.00% | Share |
| 18 | TWO SIGMA SECURITIES, LLC | 21,605 | $0 | 0.00% | Share |
| 19 | VANGUARD GROUP INC | 12,854 | $0 | 0.00% | Share |
ENSC Institutional Ownership History
| Quarter | Holders | Total Value | Change |
|---|---|---|---|
| Q4 2025 | 16 | $95.0M | +1 |
| Q3 2025 | 15 | $648.9M | +4 |
| Q2 2025 | 11 | $369.1M | +2 |
| Q1 2025 | 9 | $896.4M | +1 |
| Q4 2024 | 8 | $1.1B | +7 |
| Q3 2024 | 1 | $0 | -1 |
| Q2 2024 | 2 | $10K | +0 |
| Q1 2024 | 2 | $16K | — |
Similar Stocks by Institutional Ownership
As of Q4 2025, 19 institutional investors hold ENSC (Ensysce Biosciences, Inc.). The largest holder is PERCEPTIVE ADVISORS LLC with $79.0M in shares. This quarter, 6 institutions opened new positions and 5 closed their positions.
Frequently Asked Questions
How many hedge funds own ENSC?
As of Q4 2025, 19 institutional investors report holding ENSC (Ensysce Biosciences, Inc.) in their 13F filings.
Who is the largest institutional holder of ENSC?
The largest institutional holder of ENSC is PERCEPTIVE ADVISORS LLC with $79.0M in shares.
Is institutional ownership of ENSC increasing or decreasing?
This quarter, 6 institutions opened new positions in ENSC and 5 closed their positions.