Who Owns Cyclerion Therapeutics, Inc. (CYCN)?Hedge Fund & Institutional Holders
Institutional Holders
23
as of Q4 2025
Total Institutional Value
$1460000000000000000.0T
% of Float Held
—
QoQ Change in Holders
+5 / -2
Price History
CYCN — Biggest New Institutional Buyers This Quarter
| Fund | Action | Shares Added | Value Added |
|---|---|---|---|
| GEODE CAPITAL MANAGEMENT, LLC | Increased | +6K | +$0 |
| TWO SIGMA ADVISERS, LP | New Position | +28K | +$0 |
| XTX Topco Ltd | New Position | +10K | +$0 |
| Activest Wealth Management | New Position | +100 | +$0 |
| WHI TRUST Co LLC | New Position | +72 | +$0 |
| BANK OF AMERICA CORP /DE/ | Increased | +85 | +$0 |
| CITIGROUP INC | New Position | +8K | +$0 |
| UBS Group AG | Increased | +327 | +$-113K |
| Tower Research Capital LLC (TRC) | Increased | +826 | +$-5.4M |
| TWO SIGMA INVESTMENTS, LP | Increased | +28K | +$-30.6M |
CYCN — Institutions Reducing or Closing Positions
| Fund | Action | Shares Sold | Value Sold |
|---|---|---|---|
| Siren, L.L.C. | Decreased | -552 | -$121.2M |
| DRW Securities, LLC | Closed Position | -44K | -$100.3M |
| BARCLAYS PLC | Closed Position | -5 | -$12K |
| FMR LLC | Decreased | -6 | -$10K |
| MORGAN STANLEY | Decreased | -648 | -$1K |
Top Institutional Holders(Q4 2025)
| # | Fund | Shares | Value | % of Portfolio | Type |
|---|---|---|---|---|---|
| 1 | Siren, L.L.C. | 115,603 | $146.0M | 0.00% | Share |
| 2 | VANGUARD GROUP INC | 16,137 | $0 | 0.00% | Share |
| 3 | VANGUARD GROUP INC | 7,353 | $0 | 0.00% | Share |
| 4 | GEODE CAPITAL MANAGEMENT, LLC | 41,912 | $0 | 0.00% | Share |
| 5 | GEODE CAPITAL MANAGEMENT, LLC | 1,390 | $0 | 0.00% | Share |
| 6 | MAI Capital Management | 100 | $0 | 0.00% | Share |
| 7 | BNP PARIBAS FINANCIAL MARKETS | 5 | $0 | 0.00% | Share |
| 8 | MORGAN STANLEY | 1 | $0 | 0.00% | Share |
| 9 | BlackRock, Inc. | 16,797 | $0 | 0.00% | Share |
| 10 | WHI TRUST Co LLC | 72 | $0 | 0.00% | Share |
| 11 | Activest Wealth Management | 100 | $0 | 0.00% | Share |
| 12 | OSAIC HOLDINGS, INC. | 130 | $0 | 0.00% | Share |
| 13 | XTX Topco Ltd | 10,027 | $0 | 0.00% | Share |
| 14 | TWO SIGMA INVESTMENTS, LP | 41,555 | $0 | 0.00% | Share |
| 15 | UBS Group AG | 376 | $0 | 0.00% | Share |
| 16 | TWO SIGMA ADVISERS, LP | 28,300 | $0 | 0.00% | Share |
| 17 | Tower Research Capital LLC (TRC) | 3,154 | $0 | 0.00% | Share |
| 18 | FMR LLC | 4,740 | $0 | 0.00% | Share |
| 19 | BANK OF AMERICA CORP /DE/ | 26 | $0 | 0.00% | Share |
| 20 | BANK OF AMERICA CORP /DE/ | 75 | $0 | 0.00% | Share |
| 21 | BANK OF AMERICA CORP /DE/ | 6 | $0 | 0.00% | Share |
| 22 | GROUP ONE TRADING LLC | 192 | $0 | 0.00% | Share |
| 23 | CITIGROUP INC | 8,204 | $0 | 0.00% | Share |
CYCN Institutional Ownership History
| Quarter | Holders | Total Value | Change |
|---|---|---|---|
| Q4 2025 | 19 | $146.0M | +3 |
| Q3 2025 | 16 | $404.6M | +2 |
| Q2 2025 | 14 | $501.7M | -4 |
| Q1 2025 | 18 | $859.8M | +1 |
| Q4 2024 | 17 | $980.1M | +3 |
| Q3 2024 | 14 | $1.6B | -2 |
| Q2 2024 | 16 | $1.6B | +1 |
| Q1 2024 | 15 | $2.3B | — |
Similar Stocks by Institutional Ownership
As of Q4 2025, 23 institutional investors hold CYCN (Cyclerion Therapeutics, Inc.). The largest holder is Siren, L.L.C. with $146.0M in shares. This quarter, 5 institutions opened new positions and 2 closed their positions.
Frequently Asked Questions
How many hedge funds own CYCN?
As of Q4 2025, 23 institutional investors report holding CYCN (Cyclerion Therapeutics, Inc.) in their 13F filings.
Who is the largest institutional holder of CYCN?
The largest institutional holder of CYCN is Siren, L.L.C. with $146.0M in shares.
Is institutional ownership of CYCN increasing or decreasing?
This quarter, 5 institutions opened new positions in CYCN and 2 closed their positions.