Who Owns Aytu BioPharma, Inc. (AYTU)?Hedge Fund & Institutional Holders

$2.60-0.04 (-1.52%)HealthcareNASDAQ

Institutional Holders

46

as of Q4 2025

Total Institutional Value

$2.8252115161079562e+57T

% of Float Held

QoQ Change in Holders

+11 / -3

Price History

$1.00$1.48$1.95$2.42$2.90Sep 24Jun 25Mar 26

AYTU — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
FNY Investment Advisers, LLCIncreased+31K+$82K
BELLEVUE ASSET MANAGEMENT, LLCNew Position+25K+$65K
PERRITT CAPITAL MANAGEMENT INCNew Position+20K+$52K
Daytona Street Capital LLCNew Position+10K+$26K
ROYAL BANK OF CANADANew Position+25+$0
CITADEL ADVISORS LLCNew Position+16K+$0
DRW Securities, LLCNew Position+29K+$0
TSFG, LLCNew Position+1+$0
XTX Topco LtdNew Position+26K+$0
SBI Securities Co., Ltd.New Position+11+$0
NORTHERN TRUST CORPNew Position+19K+$0
JONES FINANCIAL COMPANIES LLLPNew Position+1+$0
BANK OF AMERICA CORP /DE/Increased+11+$-139K
OSAIC HOLDINGS, INC.Increased+5+$-803K
DIMENSIONAL FUND ADVISORS LPIncreased+4K+$-58.2M

AYTU — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
Stonepine Capital Management, LLCDecreased-78K-$1.7B
RENAISSANCE TECHNOLOGIES LLCDecreased-6K-$178.8M
Jaffetilchin Investment Partners, LLCClosed Position-17K-$32.8M
Tower Research Capital LLC (TRC)Decreased-3K-$8.1M
UBS Group AGDecreased-86-$5.9M
MORGAN STANLEYDecreased-161-$538K
FMR LLCClosed Position-5-$9K
BARCLAYS PLCClosed Position-1-$2K

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1Nantahala Capital Management, LLC1,086,812$2.8M0.09%Share
2Stonepine Capital Management, LLC813,704$2.1M1.54%Share
3AWM Investment Company, Inc.619,574$1.6M0.16%Share
4DIADEMA PARTNERS LP305,788$795K0.14%Share
5VANGUARD GROUP INC231,535$601K0.00%Share
6Persistent Asset Partners Ltd79,415$206K0.09%Share
7VANGUARD GROUP INC47,048$122K0.00%Share
8FNY Investment Advisers, LLC31,600$82K0.02%Share
9BELLEVUE ASSET MANAGEMENT, LLC25,013$65K0.02%Share
10PERRITT CAPITAL MANAGEMENT INC20,000$52K0.09%Share
11Daytona Street Capital LLC10,000$26K0.02%Share
12UBS Group AG2,787$7K0.00%Share
13DRW Securities, LLC29,368$00.00%Share
14DIMENSIONAL FUND ADVISORS LP34,027$00.00%Share
15DIMENSIONAL FUND ADVISORS LP1,336$00.00%Share
16GEODE CAPITAL MANAGEMENT, LLC54,280$00.00%Share
17GEODE CAPITAL MANAGEMENT, LLC19,817$00.00%Share
18ROYAL BANK OF CANADA25$00.00%Share
19TSFG, LLC1$00.00%Share
20TWO SIGMA INVESTMENTS, LP107,133$00.00%Share
21CITADEL ADVISORS LLC15,551$00.00%Share
22TWO SIGMA ADVISERS, LP42,500$00.00%Share
23Tower Research Capital LLC (TRC)1,713$00.00%Share
24BANK OF AMERICA CORP /DE/79$00.00%Share
25BANK OF AMERICA CORP /DE/6$00.00%Share
26NORTHERN TRUST CORP16,925$00.00%Share
27NORTHERN TRUST CORP2,244$00.00%Share
28JONES FINANCIAL COMPANIES LLLP1$00.00%Share
29MAI Capital Management3,575$00.00%Share
30BNP PARIBAS FINANCIAL MARKETS23$00.00%Share
31ACADIAN ASSET MANAGEMENT LLC10,237$00.00%Share
32MORGAN STANLEY125$00.00%Share
33BlackRock, Inc.22,793$00.00%Share
34GROUP ONE TRADING LLC37$00.00%Share
35SBI Securities Co., Ltd.11$00.00%Share
36UBS Group AG260$00.00%Share
37UBS Group AG2$00.00%Share
38VISION FINANCIAL MARKETS LLC2$00.00%Share
39NewEdge Advisors, LLC21$00.00%Share
40WELLS FARGO & COMPANY/MN12$00.00%Share
41WELLS FARGO & COMPANY/MN115$00.00%Share
42OSAIC HOLDINGS, INC.460$00.00%Share
43XTX Topco Ltd25,860$00.00%Share
44CITIGROUP INC1$00.00%Share
45RENAISSANCE TECHNOLOGIES LLC89,623$00.00%Share
46CIBC Private Wealth Group LLC83$00.00%Share

AYTU Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 202538$8.5M+8
Q3 202530$6.7B+2
Q2 202528$5.5B-2
Q1 202530$2.5B+1
Q4 202429$3.2B+8
Q3 202421$3.4T-3
Q2 202424$4.3T+0
Q1 202424$3.7T

Similar Stocks by Institutional Ownership

As of Q4 2025, 46 institutional investors hold AYTU (Aytu BioPharma, Inc.). The largest holder is Nantahala Capital Management, LLC with $2.8M in shares. This quarter, 11 institutions opened new positions and 3 closed their positions.

Frequently Asked Questions

How many hedge funds own AYTU?

As of Q4 2025, 46 institutional investors report holding AYTU (Aytu BioPharma, Inc.) in their 13F filings.

Who is the largest institutional holder of AYTU?

The largest institutional holder of AYTU is Nantahala Capital Management, LLC with $2.8M in shares.

Is institutional ownership of AYTU increasing or decreasing?

This quarter, 11 institutions opened new positions in AYTU and 3 closed their positions.