Who Owns Ardelyx, Inc. (ARDX)?Hedge Fund & Institutional Holders

$5.80+0.14 (+2.47%)HealthcareNASDAQ

Institutional Holders

50

as of Q4 2025

Total Institutional Value

$InfinityT

% of Float Held

Infinity%

QoQ Change in Holders

+6 / -3

Price History

$3.28$4.46$5.63$6.81$7.99Sep 24Jun 25Mar 26

ARDX — Biggest New Institutional Buyers This Quarter

FundActionShares AddedValue Added
MILLENNIUM MANAGEMENT LLCIncreased+4.3M+$26.9B
JONES FINANCIAL COMPANIES LLLPNew Position+1.9M+$10.0B
J. Goldman & Co LPIncreased+1.5M+$9.0B
JANUS HENDERSON GROUP PLCIncreased+691K+$6.9B
AIGH Capital Management LLCNew Position+1.1M+$6.7B
Hennion & Walsh Asset Management, Inc.New Position+960K+$5.6B
Point72 Asset Management, L.P.New Position+959K+$5.0B
FIRST TRUST ADVISORS LPIncreased+854K+$5.0B
ARROWSTREET CAPITAL, LIMITED PARTNERSHIPIncreased+846K+$4.8B
FMR LLCIncreased+656K+$3.0B
ORACLE INVESTMENT MANAGEMENT INCIncreased+369K+$2.6B
TWO SIGMA INVESTMENTS, LPIncreased+383K+$2.3B
Eversept Partners, LPIncreased+286K+$2.1B
Universal- Beteiligungs- und Servicegesellschaft mbHNew Position+348K+$2.0B
SCHRODER INVESTMENT MANAGEMENT GROUPNew Position+368K+$2.0B

ARDX — Institutions Reducing or Closing Positions

FundActionShares SoldValue Sold
FRANKLIN RESOURCES INCDecreased-601K-$70.9B
MACQUARIE GROUP LTDClosed Position-10.5M-$57.6B
MARSHALL WACE, LLPDecreased-3.8M-$49.2B
JANE STREET GROUP, LLCDecreased-133K-$12.1B
D. E. Shaw & Co., Inc.Decreased-1.9M-$11.3B
Walleye Capital LLCDecreased-990K-$6.7B
ROYAL BANK OF CANADADecreased-906K-$5.0B
Aberdeen Group plcClosed Position-866K-$4.8B
Cubist Systematic Strategies, LLCClosed Position-570K-$3.1B
Trexquant Investment LPDecreased-177K-$2.8B
JPMORGAN CHASE & CODecreased-267K-$2.5B
Squarepoint Ops LLCDecreased-51K-$2.2B
TWO SIGMA ADVISERS, LPDecreased-266K-$1.9B
BALYASNY ASSET MANAGEMENT L.P.Decreased-301K-$1.8B
CAPITAL FUND MANAGEMENT S.A.Decreased-211K-$1.7B

Top Institutional Holders(Q4 2025)

#FundSharesValue% of PortfolioType
1JANUS HENDERSON GROUP PLC14,356,672$83.0B37.17%Share
2MILLENNIUM MANAGEMENT LLC11,909,511$69.0B29.02%Share
3Nuveen, LLC3,007,636$17.0B4.45%Share
4TWO SIGMA INVESTMENTS, LP2,873,969$16.0B22.57%Share
5GOLDMAN SACHS GROUP INC2,566,531$14.0B1.73%Share
6Rock Springs Capital Management LP2,299,473$13.4B0.69%Share
7CHARLES SCHWAB INVESTMENT MANAGEMENT INC2,117,293$12.0B1.86%Share
8AQR CAPITAL MANAGEMENT LLC1,923,343$11.0B5.77%Share
9Nuveen, LLC2,035,630$11.0B2.88%Share
10ORACLE INVESTMENT MANAGEMENT INC1,872,624$10.9B6.50%Share
11NORTHERN TRUST CORP1,801,005$10.0B1.27%Share
12JONES FINANCIAL COMPANIES LLLP1,854,755$10.0B6.10%Share
13RENAISSANCE TECHNOLOGIES LLC1,794,793$10.0B15.51%Share
14Eversept Partners, LP1,715,129$10.0B0.50%Share
15J. Goldman & Co LP1,622,736$9.5B0.25%Share
16ARROWSTREET CAPITAL, LIMITED PARTNERSHIP1,424,878$8.0B4.69%Share
17D. E. Shaw & Co., Inc.1,249,723$7.0B3.84%Share
18TWO SIGMA ADVISERS, LP1,348,700$7.0B13.61%Share
19FIRST TRUST ADVISORS LP1,036,492$6.0B4.36%Share
20BANK OF AMERICA CORP /DE/1,116,228$6.0B0.44%Share
21Hennion & Walsh Asset Management, Inc.959,540$5.6B0.19%Share
22Point72 Asset Management, L.P.958,690$5.0B5.59%Share
23AIGH Capital Management LLC838,387$4.9B1.18%Share
24BANK OF AMERICA CORP /DE/724,390$4.0B0.29%Share
25BARCLAYS PLC763,189$4.0B0.96%Share
26Freestone Grove Partners LP699,133$4.0B28.92%Share
27SUSQUEHANNA INTERNATIONAL GROUP, LLP756,463$4.0B0.46%Share
28CITADEL ADVISORS LLC700,566$4.0B0.60%Share
29ORACLE INVESTMENT MANAGEMENT INC600,000$3.5B2.08%Call
30UBS Group AG553,070$3.2B0.52%Share
31FMR LLC675,945$3.0B0.15%Share
32PANAGORA ASSET MANAGEMENT INC659,160$3.0B10.63%Share
33CITADEL ADVISORS LLC626,887$3.0B0.45%Share
34Universal- Beteiligungs- und Servicegesellschaft mbH347,609$2.0B3.29%Share
35JPMORGAN CHASE & CO443,600$2.0B0.13%Share
36GOLDMAN SACHS GROUP INC498,215$2.0B0.25%Share
37SCHRODER INVESTMENT MANAGEMENT GROUP364,667$2.0B1.52%Share
38Swiss National Bank475,200$2.0B1.19%Share
39Rafferty Asset Management, LLC390,214$2.0B6.91%Share
40Y-Intercept (Hong Kong) Ltd499,668$2.0B0.04%Share
41Clay Northam Wealth Management, LLC315,015$1.8B1.02%Share
42AIGH Capital Management LLC311,613$1.8B0.44%Share
43DIADEMA PARTNERS LP252,198$1.5B0.25%Share
44GROUP ONE TRADING LLC208,700$1.2B2.12%Call
45MONIMUS CAPITAL MANAGEMENT, LP194,734$1.1B0.75%Share
46Invesco Ltd.192,538$1.1B0.17%Share
47DEUTSCHE BANK AG\300,000$1.0B0.33%Share
48Legal & General Group Plc208,188$1.0B0.22%Share
49CITADEL ADVISORS LLC231,800$1.0B0.15%Put
50BANK OF AMERICA CORP /DE/249,556$1.0B0.07%Share

ARDX Institutional Ownership History

QuarterHoldersTotal ValueChange
Q4 2025225$435.0B+51
Q3 2025174$578.4B+3
Q2 2025171$332.0B-46
Q1 2025217$650.7B+12
Q4 2024205$921.8B+38
Q3 2024167$21.4T+8
Q2 2024159$20.8T+7
Q1 2024152$773.1T—

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As of Q4 2025, 50 institutional investors hold ARDX (Ardelyx, Inc.). The largest holder is JANUS HENDERSON GROUP PLC with $83.0B in shares. This quarter, 6 institutions opened new positions and 3 closed their positions.

Frequently Asked Questions

How many hedge funds own ARDX?

As of Q4 2025, 50 institutional investors report holding ARDX (Ardelyx, Inc.) in their 13F filings.

Who is the largest institutional holder of ARDX?

The largest institutional holder of ARDX is JANUS HENDERSON GROUP PLC with $83.0B in shares.

Is institutional ownership of ARDX increasing or decreasing?

This quarter, 6 institutions opened new positions in ARDX and 3 closed their positions.