Sofinnova Investments, Inc. Q4 2019 Filing

Filed February 14, 2020

Portfolio Value

$1.4T

Holdings

59

Report Date

Q4 2019

Filing Type

13F-HR

All Holdings (59 positions)

#StockSharesValue% PortfolioType
1
ASNDAscendis Pharma A/S
1,109,874$154.4B11.13%
2
NXTCNextcure, Inc
2,671,856$150.5B10.85%
3
KRTXKaruna Therapeutics, Inc.
1,885,602$142.1B10.24%
4
AMRNAmarin
5,208,305$111.7B8.05%
5
NTRANatera
3,100,560$104.5B7.53%
6
Principia Biopharma
1,417,258$77.6B5.60%
7
YMABUSDY-mAbs Therapeutics, Inc
2,194,278$68.6B4.94%
8
GRTXGalera Therapeutics, Inc
3,083,712$40.6B2.93%
9
BMRNBiomarin Pharmaceutical Inc
441,872$37.4B2.69%
10
CHRSCoherus BioSciences
1,933,221$34.8B2.51%
11
VRTXVertex Pharmaceuticals Inc
139,164$30.5B2.20%
12
MRUSMerus N.V.
1,961,039$27.6B1.99%
13
PTCTPTC Therapeutics Inc
517,092$24.8B1.79%
14
MRKMerck & Co Inc
240,806$21.9B1.58%
15
BIIBBiogen Inc
63,711$18.9B1.36%
16
REGNRegeneron Pharmaceuticals Inc
50,086$18.8B1.36%
17
ObsEva SA
4,749,623$18.1B1.31%
18
UTHUnited Therapeutics Corp
188,645$16.6B1.20%
19
CCXIEURChemoCentryx Inc
376,944$14.9B1.07%
20
Nucana Biomed Ltd
2,400,000$14.6B1.06%
21
MyoKardia Inc
195,871$14.3B1.03%
22
MRTXEURMirati Therapeutics Inc
108,383$14.0B1.01%
23
Nucana Biomed Ltd
2,266,666$13.8B1.00%
24
MGNXMacroGenics Inc
1,173,882$12.8B0.92%
25
FATEFate Therapeutics Inc
635,143$12.4B0.90%
26
ALNYAlnylam Pharmaceuticals Inc
100,000$11.5B0.83%Call
27
SRPTSarepta Therapeutics Inc
87,818$11.3B0.82%
28
Kadmon Holdings Inc
2,368,958$10.7B0.77%
29
KNSAKiniksa Pharmaceuticals, Ltd
922,700$10.2B0.74%
30
Medicines Co
110,000$9.3B0.67%Put
31
TGTXTG Therapeutics Inc
811,292$9.0B0.65%
32
Calithera Biosciences Inc
1,458,821$8.3B0.60%
33
Dermira Inc
545,466$8.3B0.60%
34
Alexion Pharmaceuticals Inc
75,000$8.1B0.58%Call
35
Chiasma
1,630,221$8.1B0.58%
36
XLRNAcceleron Pharma Inc
147,032$7.8B0.56%
37
ITRMIterum Therapeutics
1,726,514$7.8B0.56%
38
ArQule Inc
387,469$7.7B0.56%
39
BCRXBioCryst Pharmaceuticals Inc
2,151,164$7.4B0.53%
40
Entasis Therapeutics Holdings Inc.
1,180,178$5.9B0.42%
41
OTICEUROtonomy Inc
1,515,629$5.8B0.42%
42
SGENEURSeattle Genetics Inc
50,000$5.7B0.41%
43
Forty Seven Inc
138,643$5.5B0.39%
44
Zymeworks Inc
107,552$4.9B0.35%
45
AM6Amicus Therapeutics Inc
475,330$4.6B0.33%
46
XBITXBiotech Inc
240,995$4.5B0.32%
47
ORTXUSDOrchard Therapeutics PLC
283,406$3.9B0.28%
48
Foamix Pharmaceuticals Ltd
1,162,176$3.9B0.28%
49
APLTApplied Therapeutics Inc
134,825$3.7B0.27%
50
ACRSAclaris Therapeutics
1,911,573$3.6B0.26%
51
Dicerna Pharmaceuticals Inc
159,512$3.5B0.25%
52
KALAKala Pharmaceuticals Inc
664,641$2.5B0.18%
53
APLSApellis Pharmaceuticals, Inc
49,580$1.5B0.11%
54
Synlogic Inc.
574,972$1.5B0.11%
55
FIXXEURHomology Medicines Inc
64,397$1.3B0.10%
56
HALOHalozyme Therapeutics Inc
72,481$1.3B0.09%
57
HRTXHeron Therapeutics Inc
50,500$1.2B0.09%
58
RYTMRhythm Pharmaceuticals Inc
21,319$489.0M0.04%
59
PDSBPDS Biotechnology Corporation
142,635$378.0M0.03%