Sofinnova Investments, Inc. Q3 2020 Filing

Filed November 13, 2020

Portfolio Value

$1.3T

Holdings

68

Report Date

Q3 2020

Filing Type

13F-HR

All Holdings (68 positions)

#StockSharesValue% PortfolioType
1
NTRANatera
3,100,560$224.0B16.61%
2
ASNDAscendis Pharma A/S
1,109,874$171.3B12.70%
3
KRTXKaruna Therapeutics, Inc.
1,952,441$151.0B11.19%
4
YMABUSDY-mAbs Therapeutics, Inc
2,194,278$84.2B6.25%
5
INZYInozyme Pharma, Inc.
2,028,308$53.3B3.95%
6
Checkmate Pharmaceuticals Inc
3,606,707$41.5B3.08%
7
AMGNAmgen Inc
59,500$41.2B3.06%Call
8
Akouos, Inc
1,515,073$34.6B2.57%
9
UTHUnited Therapeutics Corp
320,959$32.4B2.40%
10
ABBVAbbvie Inc
341,340$29.9B2.22%
11
Nucana Biomed Ltd
5,599,999$29.0B2.15%
12
AMGNAmgen Inc
111,619$28.4B2.10%
13
GRTXGalera Therapeutics, Inc
3,083,712$27.9B2.07%
14
NXTCNextcure, Inc
2,671,856$23.5B1.74%
15
LLYLilly Eli & Co
142,432$21.1B1.56%
16
IM8NInsmed Inc
615,143$19.8B1.47%
17
BMRNBiomarin Pharmaceutical Inc
258,653$19.7B1.46%
18
PTCTPTC Therapeutics Inc
405,152$18.9B1.40%
19
JAZZJazz Pharmaceuticals PLC
130,268$18.6B1.38%
20
MRKMerck & Co Inc
190,559$15.8B1.17%
21
MRUSMerus N.V.
1,311,039$15.7B1.17%
22
ITCIEURIntra-Cellular Therapies Inc
503,555$12.9B0.96%
23
Nucana Biomed Ltd
2,400,000$12.4B0.92%
24
ObsEva SA
4,749,623$11.8B0.87%
25
Athira Pharma, Inc.
509,168$9.4B0.70%
26
Marinus Pharmaceuticals Inc
175,000$9.0B0.67%Call
27
OTICEUROtonomy Inc
2,111,596$8.6B0.63%
28
GW Pharmaceuticals PLC
82,944$8.1B0.60%
29
CHRSCoherus BioSciences
434,555$8.0B0.59%
30
CYTKCytokinetics Inc
349,296$7.6B0.56%
31
Zymeworks Inc
151,902$7.1B0.52%
32
CYTKCytokinetics Inc
325,000$7.0B0.52%Put
33
PTGXProtagonist Therapeutics Inc
357,769$7.0B0.52%
34
KURAKura Oncology Inc
225,259$6.9B0.51%
35
SUPNSupernus Pharmaceuticals Inc
330,295$6.9B0.51%
36
TGTXTG Therapeutics Inc
250,401$6.7B0.50%
37
XLRNAcceleron Pharma Inc
59,546$6.7B0.50%
38
RETAEURReata Pharmaceuticals Inc
68,615$6.7B0.50%
39
MyoKardia Inc
48,998$6.7B0.50%
40
ARNAEURArena Pharmaceuticals Inc
88,150$6.6B0.49%
41
OVIDOvid Therapeutics Inc
1,097,621$6.3B0.47%
42
MIRMMirum Pharmaceuticals Inc
321,252$6.2B0.46%
43
Reata Pharmaceuticals Inc
60,000$5.8B0.43%Put
44
NVCRNovocure Ltd
50,000$5.6B0.41%Call
45
AMRNAmarin Corp
1,170,584$4.9B0.37%
46
ACRSAclaris Therapeutics
1,911,573$4.9B0.36%
47
PBYIPuma Biotechnology Inc
475,982$4.8B0.36%
48
Chiasma
1,047,354$4.5B0.33%
49
CCXIEURChemoCentryx Inc
81,235$4.5B0.33%
50
KNSAKiniksa Pharmaceuticals, Ltd
276,628$4.2B0.31%
51
Applied Genetic Technologies Corp
825,071$4.0B0.30%
52
MRNAModerna Inc
50,000$3.5B0.26%Call
53
TCR2 Therapeutics Inc
173,028$3.5B0.26%
54
IMTXImmatics NV
325,527$3.5B0.26%
55
LQDALiquidia Technologies Inc
679,400$3.3B0.25%
56
BCRXBioCryst Pharmaceuticals Inc
793,054$2.7B0.20%
57
FIXXEURHomology Medicines Inc
238,015$2.5B0.19%
58
Kadmon Holdings Inc
629,923$2.5B0.18%
59
CGENCompugen Ltd
146,592$2.4B0.18%
60
Entasis Therapeutics Holdings Inc.
1,012,408$2.1B0.15%
61
ACADACADIA Pharmaceuticals Inc
48,996$2.0B0.15%
62
Calithera Biosciences Inc
493,297$1.7B0.13%
63
FATEFate Therapeutics Inc
41,400$1.7B0.12%
64
RGNXRegenxbio Inc
59,507$1.6B0.12%
65
Synlogic Inc.
574,972$1.2B0.09%
66
YB4PSavara Inc
375,591$409.0M0.03%
67
PDSBPDS Biotechnology Corporation
142,635$332.0M0.02%
68
Kadmon Holdings Inc
240,091$137.0M0.01%