ORBIMED ADVISORS LLC Q1 2016 Filing
Filed May 16, 2016
Portfolio Value
$9.5B
Holdings
138
Report Date
Q1 2016
Filing Type
13F-HR
All Holdings (138 positions)
| # | Stock | Shares | Value | % Portfolio | Type |
|---|---|---|---|---|---|
| 1 | BMYBRISTOL MYERS SQUIBB CO | 7,624,900 | $487.1B | 5125.19% | |
| 2 | —ALLERGAN PLC | 1,672,715 | $448.3B | 4717.55% | Call |
| 3 | HCAHCA HOLDINGS INC | 5,737,100 | $447.8B | 4711.68% | |
| 4 | AMGNAMGEN INC | 2,876,000 | $431.2B | 4537.20% | |
| 5 | BSXBOSTON SCIENTIFIC CORP | 22,479,700 | $422.8B | 4449.28% | |
| 6 | ABBVABBVIE INC | 7,395,700 | $422.4B | 4445.06% | |
| 7 | BIIBBIOGEN INC | 1,526,300 | $397.3B | 4180.78% | |
| 8 | CELGCELGENE CORP | 3,774,077 | $377.7B | 3974.77% | |
| 9 | GILDGILEAD SCIENCES INC | 3,019,200 | $277.3B | 2918.30% | |
| 10 | ALXNALEXION PHARMACEUTICALS INC | 1,870,600 | $260.4B | 2740.27% | |
| 11 | —IMPAX LABORATORIES INC | 6,776,100 | $217.0B | 2283.03% | |
| 12 | TMOTHERMO FISHER SCIENTIFIC INC | 1,435,000 | $203.2B | 2137.94% | |
| 13 | INCYINCYTE CORP | 2,755,078 | $199.7B | 2100.89% | |
| 14 | REGNREGENERON PHARMACEUTICALS | 533,000 | $192.1B | 2021.49% | |
| 15 | LLYLILLY ELI & CO | 2,541,300 | $183.0B | 1925.57% | |
| 16 | WCGEURWELLCARE HEALTH PLANS INC | 1,903,300 | $176.5B | 1857.51% | |
| 17 | ISRGINTUITIVE SURGICAL INC | 276,800 | $166.4B | 1750.60% | |
| 18 | —EXPRESS SCRIPTS HLDG CO | 2,421,000 | $166.3B | 1749.84% | |
| 19 | VRTXVERTEX PHARMACEUTICALS INC | 1,869,400 | $148.6B | 1563.60% | |
| 20 | ILMNILLUMINA INC | 900,000 | $145.9B | 1535.19% | |
| 21 | TEVATEVA PHARMACEUTICAL INDS LTD | 2,696,000 | $144.3B | 1517.98% | |
| 22 | ICPTUSDINTERCEPT PHARMACEUTICALS IN | 1,120,000 | $143.9B | 1514.01% | |
| 23 | AG8AGILENT TECHNOLOGIES INC | 3,495,000 | $139.3B | 1465.50% | |
| 24 | —WRIGHT MED GROUP N V | 8,345,110 | $138.5B | 1457.64% | |
| 25 | —MAGELLAN HEALTH INC | 1,909,000 | $129.7B | 1364.51% | |
| 26 | IRWDIRONWOOD PHARMACEUTICALS INC | 11,550,400 | $126.4B | 1329.61% | |
| 27 | COOCOOPER COS INC | 795,900 | $122.5B | 1289.45% | |
| 28 | PFEPFIZER INC | 4,122,000 | $122.2B | 1285.57% | |
| 29 | NBIXNEUROCRINE BIOSCIENCES INC | 2,653,874 | $105.0B | 1104.43% | |
| 30 | UNHUNITEDHEALTH GROUP INC | 812,000 | $104.7B | 1101.34% | |
| 31 | —RELYPSA INC | 7,400,000 | $100.3B | 1055.07% | |
| 32 | —ALLERGAN PLC | 104,200 | $95.8B | 1007.76% | |
| 33 | —ACHILLION PHARMACEUTICALS IN | 11,719,700 | $90.5B | 952.02% | Call |
| 34 | —OPHTHOTECH CORP | 2,094,500 | $88.5B | 931.59% | |
| 35 | BMRNBIOMARIN PHARMACEUTICAL INC | 1,023,200 | $84.4B | 888.02% | |
| 36 | —TESARO INC | 1,912,000 | $84.2B | 885.82% | |
| 37 | PBYIPUMA BIOTECHNOLOGY INC | 2,753,425 | $80.9B | 850.92% | |
| 38 | —MALLINCKRODT PUB LTD CO | 1,309,000 | $80.2B | 844.06% | |
| 39 | CRVSCORVUS PHARMACEUTICALS INC | 5,258,450 | $76.2B | 802.30% | |
| 40 | INSYEURINSYS THERAPEUTICS INC NEW | 4,557,740 | $72.9B | 766.84% | |
| 41 | NUVAGBPNUVASIVE INC | 1,487,000 | $72.3B | 761.21% | |
| 42 | HUMHUMANA INC | 339,700 | $62.1B | 653.94% | |
| 43 | —LOXO ONCOLOGY INC | 2,175,857 | $59.5B | 625.95% | |
| 44 | JNJJOHNSON & JOHNSON | 531,800 | $57.5B | 605.46% | |
| 45 | IMGNEURIMMUNOGEN INC | 6,095,647 | $51.9B | 546.48% | |
| 46 | —SHIRE PLC | 300,371 | $51.6B | 543.31% | |
| 47 | XBISPDR SERIES TRUST | 981,200 | $50.7B | 533.36% | |
| 48 | MDTMEDTRONIC PLC | 666,299 | $50.0B | 525.82% | |
| 49 | GKOSGLAUKOS CORP | 2,897,938 | $48.9B | 514.11% | |
| 50 | CICIGNA CORPORATION | 335,500 | $46.0B | 484.49% | |
| 51 | IM8NINSMED INC | 3,469,900 | $44.0B | 462.60% | |
| 52 | —DIMENSION THERAPEUTICS INC | 5,397,698 | $42.3B | 444.71% | |
| 53 | CYHCOMMUNITY HEALTH SYS INC NEW | 2,171,400 | $40.2B | 422.92% | |
| 54 | —BLUEBIRD BIO INC | 945,500 | $40.2B | 422.83% | |
| 55 | ACADACADIA PHARMACEUTICALS INC | 1,401,600 | $39.2B | 412.36% | |
| 56 | DVAXDYNAVAX TECHNOLOGIES CORP | 1,974,700 | $38.0B | 399.77% | |
| 57 | VRAYQVIEWRAY INC | 7,989,916 | $34.4B | 361.51% | |
| 58 | ARRYEURARRAY BIOPHARMA INC | 10,689,000 | $31.5B | 331.80% | |
| 59 | IBBISHARES TR | 111,700 | $29.1B | 306.54% | |
| 60 | OTICEUROTONOMY INC | 1,850,094 | $27.6B | 290.45% | |
| 61 | —XENOPORT INC | 6,000,400 | $27.1B | 284.75% | |
| 62 | —MEDIVATION INC | 501,000 | $23.0B | 242.39% | |
| 63 | SYKSTRYKER CORP | 212,000 | $22.7B | 239.33% | |
| 64 | —IMMUNOMEDICS INC | 30,000,000 | $20.4B | 214.49% | |
| 65 | INFIQINFINITY PHARMACEUTICALS INC | 3,723,528 | $19.6B | 206.48% | |
| 66 | —PORTOLA PHARMACEUTICALS INC | 938,100 | $19.1B | 201.37% | Put |
| 67 | SVASINOVAC BIOTECH LTD | 2,667,500 | $17.0B | 179.35% | |
| 68 | —NEWLINK GENETICS CORP | 817,006 | $14.9B | 156.47% | |
| 69 | XNCRXENCOR INC | 1,107,022 | $14.9B | 156.32% | |
| 70 | —AFFIMED N V | 3,931,800 | $14.7B | 154.73% | |
| 71 | FLBFLUIDIGM CORP DEL | 1,746,100 | $14.1B | 148.27% | |
| 72 | PIRSPIERIS PHARMACEUTICALS INC | 7,259,620 | $13.8B | 145.13% | |
| 73 | —GW PHARMACEUTICALS PLC | 190,600 | $13.8B | 144.70% | |
| 74 | CAHCARDINAL HEALTH INC | 166,000 | $13.6B | 143.15% | |
| 75 | —FORWARD PHARMA A/S | 798,000 | $13.6B | 142.75% | |
| 76 | —CYNAPSUS THERAPEUTICS INC | 1,140,325 | $13.2B | 139.12% | |
| 77 | —BAXALTA INC | 326,000 | $13.2B | 138.58% | |
| 78 | EXASEXACT SCIENCES CORP | 1,890,400 | $12.7B | 134.06% | |
| 79 | CLVSEURCLOVIS ONCOLOGY INC | 660,900 | $12.7B | 133.52% | |
| 80 | EHTHEHEALTH INC | 1,300,000 | $12.2B | 128.45% | |
| 81 | NTRANATERA INC | 1,276,190 | $12.1B | 127.84% | |
| 82 | MCKMCKESSON CORP | 77,200 | $12.1B | 127.74% | |
| 83 | —NABRIVA THERAPEUTICS AG | 1,315,000 | $11.8B | 123.97% | |
| 84 | JAZZJAZZ PHARMACEUTICALS PLC | 90,000 | $11.8B | 123.64% | |
| 85 | ENSGENSIGN GROUP INC | 514,200 | $11.6B | 122.49% | |
| 86 | PRQRPROQR THRAPEUTICS N V | 2,305,446 | $11.3B | 118.39% | |
| 87 | MRKMERCK & CO INC NEW | 210,400 | $11.1B | 117.13% | |
| 88 | —HORIZON PHARMA INVT LTD | 13,000,000 | $11.1B | 117.09% | |
| 89 | ZBHZIMMER BIOMET HLDGS INC | 103,000 | $11.0B | 115.57% | |
| 90 | —PRONAI THERAPEUTICS INC | 1,623,149 | $10.9B | 115.11% | |
| 91 | —INOTEK PHARMACEUTICALS CORP | 1,391,000 | $10.3B | 108.31% | |
| 92 | EWEDWARDS LIFESCIENCES CORP | 115,000 | $10.1B | 106.74% | |
| 93 | SNDXSYNDAX PHARMACEUTICALS INC | 757,365 | $10.1B | 106.15% | |
| 94 | ABTABBOTT LABS | 237,000 | $9.9B | 104.32% | |
| 95 | CLLSCELLECTIS S A | 350,000 | $9.6B | 101.28% | |
| 96 | GLPGGALAPAGOS NV | 230,000 | $9.6B | 101.21% | |
| 97 | —IMMUNOMEDICS INC | 3,802,000 | $9.5B | 100.01% | |
| 98 | SIENUSDSIENTRA INC | 1,357,500 | $9.3B | 97.70% | |
| 99 | —AETNA INC NEW | 76,000 | $8.5B | 89.85% | |
| 100 | ITCIEURINTRA CELLULAR THERAPIES INC | 294,000 | $8.2B | 86.00% |
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