BAKER BROS. ADVISORS LP Q4 2016 Filing

Filed February 14, 2017

Portfolio Value

$10.2B

Holdings

133

Report Date

Q4 2016

Filing Type

13F-HR

All Holdings (133 positions)

#StockSharesValue% PortfolioType
101
MyoKardia, Inc.
100,000$1.3B12.69%
102
QUREuniQure N.V.
230,000$1.3B12.63%
103
MCRB1EURSeres Therapeutics, Inc.
125,000$1.2B12.14%
104
Colucid Pharmaceuticals, Inc.
30,310$1.1B10.81%
105
Ritter Pharmaceuticals, Inc.
400,000$1.1B10.63%
106
PRQRProQR Therapeutics N.V.
212,698$1.0B10.21%
107
Palatin Technologies, Inc.
2,050,000$1.0B10.15%
108
MediWound Ltd.
226,000$1.0B10.15%
109
Five Prime Therapeutics, Inc.
19,247$964.0M9.45%
110
MDGLMadrigal Pharmaceuticals, Inc.
57,762$861.0M8.44%
111
CLLSCellectis S.A.
50,000$848.0M8.31%
112
Immune Design Corp.
148,937$819.0M8.03%
113
Tenax Therapeutics, Inc.
420,000$819.0M8.03%
114
INFIQInfinity Pharmaceuticals, Inc.
580,400$784.0M7.69%
115
ALDXAldeyra Therapeutics, Inc.
142,000$760.0M7.45%
116
Proteon Therapeutics, Inc.
389,394$740.0M7.25%
117
XLRNAcceleron Pharma Inc.
28,765$734.0M7.20%
118
Affimed N.V.
400,000$720.0M7.06%
119
CBAYUSDCymaBay Therapeutics, Inc.
309,268$535.0M5.24%
120
CMRXEURChimerix, Inc.
115,216$530.0M5.20%
121
I9DNArbutus Biopharma Corporation
180,582$442.0M4.33%
122
ALNYAlnylam Pharmaceuticals, Inc.
11,340$425.0M4.17%
123
ADAPYAdaptimmune Therapeutics plc
100,000$405.0M3.97%
124
Foundation Medicine, Inc.
20,892$370.0M3.63%
125
BioDelivery Sciences International, Inc.
210,021$368.0M3.61%
126
CCXIEURChemoCentryx, Inc.
49,064$363.0M3.56%
127
Aptose Biosciences Inc.
258,311$359.0M3.52%
128
Windtree Therapeutics, Inc.
254,973$319.0M3.13%
129
ProNAi Therapeutics, Inc.
200,000$298.0M2.92%
130
DVAXDynavax Technologies Corporation
75,000$296.0M2.90%
131
La Jolla Pharmaceutical Company
13,746$241.0M2.36%
132
BGMS 6 PERPCyclacel Pharmaceuticals, Inc.
13,253$82.0M0.80%
133
BioTime, Inc.
20,084$14.0M0.14%
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